Found 15 Enz. Inhib. hit(s) with all data for entry = 50009499 TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Inhibition of wild type BCR/Abl (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 hrs ...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of wild type BCR/Abl (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 hrs ...More data for this Ligand-Target Pair
3D Structure (crystal)TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of BCR/Abl F317I mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of BCR/Abl Q252H mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of BCR/Abl M351T mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of BCR/Abl M351T mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of BCR/Abl F317I mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of BCR/Abl Q252H mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 144nMAssay Description:Inhibition of wild type BCR/Abl (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 hrs ...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 318nMAssay Description:Inhibition of BCR/Abl Y253F mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 347nMAssay Description:Inhibition of BCR/Abl Y253F mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 364nMAssay Description:Inhibition of BCR/Abl F317I mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 487nMAssay Description:Inhibition of BCR/Abl Q252H mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 799nMAssay Description:Inhibition of BCR/Abl M351T mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Peking Union Medical College And Chinese Academy Of Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 8.78E+3nMAssay Description:Inhibition of BCR/Abl Y253F mutant (unknown origin) transfected in mouse Ba/F3 cells assessed as inhibition of cell proliferation measured after 72 h...More data for this Ligand-Target Pair
