Found 12 Enz. Inhib. hit(s) with all data for entry = 50008548 
Affinity DataIC50: <1nMAssay Description:Inhibition of beta2 adrenoreceptor (unknown origin)More data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Frontier Medicines
Curated by ChEMBL
Frontier Medicines
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of human N-myristoyltransferase assessed as reduction in CoASH production by fluorogenic detection based assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Frontier Medicines
Curated by ChEMBL
Frontier Medicines
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human PDE10A2 using cAMP substrate by HTRF assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Frontier Medicines
Curated by ChEMBL
Frontier Medicines
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of GST-tagged human recombinant DYRK1A expressed in Escherichia coli using GRSRSRSRSRSR peptide substrate in presence of [gamma-33P]-ATP i...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Frontier Medicines
Curated by ChEMBL
Frontier Medicines
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of GST-tagged human recombinant DYRK1A expressed in Escherichia coli using GRSRSRSRSRSR peptide substrate in presence of [gamma-33P]-ATP i...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of beta2 adrenoreceptor (unknown origin)More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Frontier Medicines
Curated by ChEMBL
Frontier Medicines
Curated by ChEMBL
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of human PDE10A2 using cAMP substrate by HTRF assayMore data for this Ligand-Target Pair
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Frontier Medicines
Curated by ChEMBL
Frontier Medicines
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human N-myristoyltransferase assessed as reduction in CoASH production by fluorogenic detection based assayMore data for this Ligand-Target Pair
Affinity DataKd: >3.70E+5nMAssay Description:Inhibition GST-tagged recombinant HRAS G12V mutant (1 to 166 amino acids) (unknown origin) expressed in Escherichia coli C41(DE3) by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.30E+4nMAssay Description:Binding affinity to Poly-Histidine-tagged CBP (unknown origin) expressed in Escherichia coli BL21(DE3) by competition binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 51nMAssay Description:Inhibition GST-tagged recombinant HRAS G12V mutant (1 to 166 amino acids) (unknown origin) expressed in Escherichia coli C41(DE3) by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 35nMAssay Description:Binding affinity to Poly-Histidine-tagged CBP (unknown origin) expressed in Escherichia coli BL21(DE3) by competition binding assayMore data for this Ligand-Target Pair
