Compile Data Set for Download or QSAR
maximum 50k data
Found 27 Enz. Inhib. hit(s) with all data for entry = 50007976
LigandPNGBDBM50204093(BAY 80-6946 | BAY-80-6946 | Copanlisib)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50514596(CHEMBL4455710)
Affinity DataIC50:  0.170nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514593(CHEMBL4470122)
Affinity DataIC50:  0.170nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50204093(BAY 80-6946 | BAY-80-6946 | Copanlisib)
Affinity DataIC50:  0.180nMAssay Description:Inhibition of human full-length His-tagged p110delta/p85alpha expressed in baculovirus expression system using PIP2 as substrate measured after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50514597(CHEMBL4475217)
Affinity DataIC50:  0.190nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514589(CHEMBL4534475)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514590(CHEMBL4440406)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514595(CHEMBL4516974)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514588(CHEMBL4439080)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514591(CHEMBL4577573)
Affinity DataIC50:  0.230nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514599(CHEMBL4437362)
Affinity DataIC50:  0.230nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514592(CHEMBL4580837)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514601(CHEMBL4444638)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514602(CHEMBL4449613)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50456923(CHEMBL4213353)
Affinity DataIC50:  0.310nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514598(CHEMBL4536505)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514600(CHEMBL4441605)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514590(CHEMBL4440406)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human full-length His-tagged p110delta/p85alpha expressed in baculovirus expression system using PIP2 as substrate measured after 1 hr ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50514590(CHEMBL4440406)
Affinity DataIC50:  0.580nMAssay Description:Inhibition of recombinant human full-length His-tagged p110beta/p85alpha expressed in baculovirus expression system using PIP2 as substrate measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50514590(CHEMBL4440406)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of recombinant human full-length His-tagged p110gamma expressed in baculovirus expression system using PIP2 as substrate measured after 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50204093(BAY 80-6946 | BAY-80-6946 | Copanlisib)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of recombinant human full-length His-tagged p110gamma expressed in baculovirus expression system using PIP2 as substrate measured after 1 ...More data for this Ligand-Target Pair
LigandPNGBDBM50514594(CHEMBL4461136)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
LigandPNGBDBM50204093(BAY 80-6946 | BAY-80-6946 | Copanlisib)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of recombinant human full-length His-tagged p110beta/p85alpha expressed in baculovirus expression system using PIP2 as substrate measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50341493(CHEMBL1765463 | Ethyl 6-(5-(Phenylsulfonamido)pyri...)
Affinity DataIC50: >5nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged p110alpha/p85alpha expressed in baculovirus expression system using PIP2 as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50514590(CHEMBL4440406)
Affinity DataIC50:  21nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362 to end residues) using ULight-4E-BP1 (Thr37/46) as substrate measured after 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50204093(BAY 80-6946 | BAY-80-6946 | Copanlisib)
Affinity DataIC50:  45nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed