Compile Data Set for Download or QSAR
maximum 50k data
Found 35 Enz. Inhib. hit(s) with all data for entry = 310
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285971(CHEMBL95546 | [(1S,2R)-1-Benzyl-3-((3aR,6S,7aS)-6-...)
Affinity DataIC50:  0.260nMAssay Description:In vitro inhibition of HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM318((2R,3R)-2-(propan-2-yl)thiolan-3-yl N-[(2S,3R)-4-[...)
Affinity DataIC50:  0.260nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM306((2S,3S)-2-methyloxolan-3-yl N-[(2R,3R)-4-[(3aR,7aS...)
Affinity DataIC50:  0.280nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285969(CHEMBL99336 | [(1R,2R)-3-((3aR,6S,7aS)-6-tert-Buty...)
Affinity DataIC50:  0.280nMAssay Description:In vitro inhibition of HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285976(CHEMBL321949 | [(1R,2R)-3-((3aR,6S,7aS)-6-tert-But...)
Affinity DataIC50:  0.400nMAssay Description:In vitro inhibition of HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM313((2S,3S)-2-methyl-1,1-dioxo--thiolan-3-yl N-[(2R,3R...)
Affinity DataIC50:  0.400nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM322((2R,3R)-1,1-dioxo-2-(propan-2-yl)--thiolan-3-yl N-...)
Affinity DataIC50:  0.420nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285980(CHEMBL97585 | LY-326188 | [(1R,2R)-3-((3aR,6S,7aS)...)
Affinity DataIC50:  0.420nMAssay Description:In vitro inhibition of HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285977(CHEMBL99214 | [(1R,2R)-3-((3aR,6S,7aS)-6-tert-Buty...)
Affinity DataIC50:  0.75nMAssay Description:In vitro inhibition of HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM314((2R,3R)-2-methyl-1,1-dioxo--thiolan-3-yl N-[(2R,3R...)
Affinity DataIC50:  0.75nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM321((2S,3S)-1,1-dioxo-2-(propan-2-yl)--thiolan-3-yl N-...)
Affinity DataIC50:  0.950nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285982(CHEMBL316717 | [(1R,2R)-3-((3aR,6S,7aS)-6-tert-But...)
Affinity DataIC50:  0.950nMAssay Description:In vitro inhibition of HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM519((2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarba...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibition of HIV-1 protease.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285975(CHEMBL316718 | [(1S,2R)-1-Benzyl-3-((3aR,6S,7aS)-6...)
Affinity DataIC50:  1.30nMAssay Description:In vitro inhibition of HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM320((2R,3R)-1,1-dioxo-2-(propan-2-yl)--thiolan-3-yl N-...)
Affinity DataIC50:  1.30nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM312((2S,3R)-2-methyl-1,1-dioxo--thiolan-3-yl N-[(2R,3R...)
Affinity DataIC50:  1.40nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285970(CHEMBL318129 | [(1R,2R)-3-((3aR,6S,7aS)-6-tert-But...)
Affinity DataIC50:  1.40nMAssay Description:In vitro inhibition of HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM308((3S)-1,1-dioxo--thiolan-3-yl N-[(2R,3R)-4-[(3aR,7a...)
Affinity DataIC50:  1.70nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285974(CHEMBL100048 | [(1R,2R)-3-((3aR,6S,7aS)-6-tert-But...)
Affinity DataIC50:  1.70nMAssay Description:In vitro inhibition of HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM309((3R)-1,1-dioxo--thiolan-3-yl N-[(2R,3R)-4-[(3aR,7a...)
Affinity DataIC50:  2nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285979(CHEMBL316608 | [(1R,2R)-3-((3aR,6S,7aS)-6-tert-But...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibition of HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285978(CHEMBL100271 | [(1S,2R)-1-Benzyl-3-((3aR,6S,7aS)-6...)
Affinity DataIC50:  2.60nMAssay Description:In vitro inhibition of HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM317((2S,3S)-2-(propan-2-yl)thiolan-3-yl N-[(2S,3R)-4-[...)
Affinity DataIC50:  2.60nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285972(CHEMBL321778 | [(1S,2R)-1-Benzyl-3-((3aR,6S,7aS)-6...)
Affinity DataIC50:  2.60nMAssay Description:In vitro inhibition of HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM319((2S,3S)-1,1-dioxo-2-(propan-2-yl)--thiolan-3-yl N-...)
Affinity DataIC50:  2.60nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285981(CHEMBL318894 | [(1R,2R)-3-((3aR,6S,7aS)-6-tert-But...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM307((2R,3R)-2-methyloxolan-3-yl N-[(2R,3R)-4-[(3aR,7aS...)
Affinity DataIC50:  3nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM316((2R,3R)-1,1-dioxo-2-(propan-2-yl)--thiolan-3-yl N-...)
Affinity DataIC50:  4.30nMAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285968(CHEMBL18067 | [(1S,2R)-1-Benzyl-3-((3S,4aS,8aS)-3-...)
Affinity DataIC50:  4.30nMAssay Description:In vitro inhibition of HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM311((2R,3S)-2-methyl-1,1-dioxo--thiolan-3-yl N-[(2R,3R...)
Affinity DataIC50:  5.20nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285967(CHEMBL320602 | [(1R,2R)-3-((3aR,6S,7aS)-6-tert-But...)
Affinity DataIC50:  5.20nMAssay Description:In vitro inhibition of HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM50285973(CHEMBL261340 | [(1S,2R)-1-Benzyl-3-((3S,4aS,8aS)-3...)
Affinity DataIC50:  8.10nMAssay Description:In vitro inhibition of HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM315((2S,3S)-1,1-dioxo-2-(propan-2-yl)--thiolan-3-yl N-...)
Affinity DataIC50:  8.10nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM310((2R,3R)-2-methyl-1,1-dioxo--thiolan-3-yl N-[(2S,3R...)
Affinity DataIC50:  10nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM532((2R,3R)-2-methyl-1,1-dioxo--thiolan-3-yl N-[(2S,3R...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibition of HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article