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Found 6 Enz. Inhib. hit(s) with all data for entry = 50028903
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280050(5-Methyl-2-[2-(10H-phenothiazin-2-yloxy)-ethyl]-2,...)
Affinity DataIC50:  57nMAssay Description:Inhibition of [14C]-arachidonic acid conversion to 5-HETE by broken cell 5-LO isolated from guinea pig PMNMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280049(5-Methyl-2-[2-(10H-phenothiazin-3-yloxy)-ethyl]-2,...)
Affinity DataIC50:  61nMAssay Description:Inhibition of [14C]-arachidonic acid conversion to 5-HETE by broken cell 5-LO isolated from guinea pig PMNMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280048(5-Methyl-2-[2-(10H-phenoxazin-2-yloxy)-ethyl]-2,4-...)
Affinity DataIC50:  110nMAssay Description:Inhibition of [14C]-arachidonic acid conversion to 5-HETE by broken cell 5-LO isolated from guinea pig PMNMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280047(2-[2-(Naphthalen-2-yloxy)-ethyl]-2,3a,4,5,6,7-hexa...)
Affinity DataIC50:  310nMAssay Description:Inhibition of [14C]-arachidonic acid conversion to 5-HETE by broken cell 5-LO isolated from guinea pig PMNMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280046(2-[2-(Naphthalen-2-yloxy)-ethyl]-3a,4,5,6-tetrahyd...)
Affinity DataIC50:  480nMAssay Description:Inhibition of [14C]-arachidonic acid conversion to 5-HETE by broken cell 5-LO isolated from guinea pig PMNMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50008999(5-Methyl-2-[2-(naphthalen-2-yloxy)-ethyl]-2,4-dihy...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of [14C]-arachidonic acid conversion to 5-HETE by broken cell 5-LO isolated from guinea pig PMNMore data for this Ligand-Target Pair
In DepthDetails Article