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Articleid 50029577

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50076394
PNG
(2-Amino-bicyclo[2.2.1]heptane-2,7-dicarboxylic aci...)
Show SMILES NC1(CC2CCC1C2C(O)=O)C(O)=O
Show InChI InChI=1S/C9H13NO4/c10-9(8(13)14)3-4-1-2-5(9)6(4)7(11)12/h4-6H,1-3,10H2,(H,11,12)(H,13,14)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 6.30E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of the 1S,3R-ACPD stimulation of IP formation by the compound in LLC-PK1 cells expressing Metabotropic glutamate receptor (mGluRla)


Bioorg Med Chem Lett 5: 2627-2632 (1995)


Article DOI: 10.1016/0960-894X(95)00457-5
BindingDB Entry DOI: 10.7270/Q27944NK
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50076394
PNG
(2-Amino-bicyclo[2.2.1]heptane-2,7-dicarboxylic aci...)
Show SMILES NC1(CC2CCC1C2C(O)=O)C(O)=O
Show InChI InChI=1S/C9H13NO4/c10-9(8(13)14)3-4-1-2-5(9)6(4)7(11)12/h4-6H,1-3,10H2,(H,11,12)(H,13,14)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/an/an/a 9.30E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for inhibitory binding activity towards metabotropic glutamate receptor (mGluRla) expressed in LLC-PK1 cells


Bioorg Med Chem Lett 5: 2627-2632 (1995)


Article DOI: 10.1016/0960-894X(95)00457-5
BindingDB Entry DOI: 10.7270/Q27944NK
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%