Compile Data Set for Download or QSAR
maximum 50k data
Found 20 Enz. Inhib. hit(s) with all data for entry = 50029709
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50031839(((E)-6,10-Dimethyl-1-phosphono-undeca-5,9-dienyl)-...)
Affinity DataIC50:  17nMAssay Description:Inhibition of squalene synthase from rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50059875((S)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...)
Affinity DataIC50:  80nMAssay Description:Inhibition of farnesyl protein transferase from bovine brainMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50287113((S)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...)
Affinity DataIC50:  90nMAssay Description:Inhibition of squalene synthase from rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50287113((S)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...)
Affinity DataIC50:  170nMAssay Description:Inhibition of farnesyl protein transferase from bovine brainMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50287115((S)-3-Phenyl-2-((5E,9E)-6,10,14-trimethyl-3-phosph...)
Affinity DataIC50:  220nMAssay Description:Inhibition of squalene synthase from rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50059860(((2E,6E)-1-Hydroxy-3,7,11-trimethyl-dodeca-2,6,10-...)
Affinity DataIC50:  410nMAssay Description:Inhibition of farnesyl protein transferase from bovine brainMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50287115((S)-3-Phenyl-2-((5E,9E)-6,10,14-trimethyl-3-phosph...)
Affinity DataIC50:  470nMAssay Description:Inhibition of farnesyl protein transferase from bovine brainMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50287116(((3E,7E)-4,8,12-Trimethyl-1-phenethylcarbamoyl-tri...)
Affinity DataIC50:  480nMAssay Description:Inhibition of squalene synthase from rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50287118((R)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...)
Affinity DataIC50:  500nMAssay Description:Inhibition of squalene synthase from rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50287118((R)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...)
Affinity DataIC50:  980nMAssay Description:Inhibition of farnesyl protein transferase from bovine brainMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50059875((S)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of squalene synthase from rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50287117((S)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of squalene synthase from rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50059860(((2E,6E)-1-Hydroxy-3,7,11-trimethyl-dodeca-2,6,10-...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of squalene synthase from rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50287114((4E,8E)-2-(1-Carboxy-2-phenyl-ethylcarbamoyl)-5,9,...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of squalene synthase from rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene synthase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50287112((S)-3-Phenyl-2-[(4E,8E)-5,9,13-trimethyl-2-(2-phos...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of squalene synthase from rat liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50287112((S)-3-Phenyl-2-[(4E,8E)-5,9,13-trimethyl-2-(2-phos...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of farnesyl protein transferase from bovine brainMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50287116(((3E,7E)-4,8,12-Trimethyl-1-phenethylcarbamoyl-tri...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of farnesyl protein transferase from bovine brainMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50287114((4E,8E)-2-(1-Carboxy-2-phenyl-ethylcarbamoyl)-5,9,...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of farnesyl protein transferase from bovine brainMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50031839(((E)-6,10-Dimethyl-1-phosphono-undeca-5,9-dienyl)-...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of farnesyl protein transferase from bovine brainMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50287117((S)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Farnesyltransferase from bovine brainMore data for this Ligand-Target Pair
In DepthDetails Article