Compile Data Set for Download or QSAR
maximum 50k data
Found 61 Enz. Inhib. hit(s) with all data for entry = 50029838
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288548(2-Acridin-9-yl-2-benzo[1,3]dioxol-5-yl-ethanol | C...)
Affinity DataIC50:  900nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288548(2-Acridin-9-yl-2-benzo[1,3]dioxol-5-yl-ethanol | C...)
Affinity DataIC50:  900nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288543(Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetaldehyde | ...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288538((Acridin-9-yloxy)-benzo[1,3]dioxol-5-yl-acetic aci...)
Affinity DataIC50:  2.20E+3nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288537(Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid met...)
Affinity DataIC50:  2.80E+3nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288545(Benzo[1,3]dioxol-5-yl-(2-methyl-quinolin-4-yl)-ace...)
Affinity DataIC50:  2.80E+3nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288537(Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid met...)
Affinity DataIC50:  4.30E+3nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288538((Acridin-9-yloxy)-benzo[1,3]dioxol-5-yl-acetic aci...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288532(Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid ter...)
Affinity DataIC50:  5.60E+3nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288537(Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid met...)
Affinity DataIC50:  5.80E+3nMAssay Description:Compound was tested for inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288550(Benzo[1,3]dioxol-5-yl-(1,2,3,4-tetrahydro-acridin-...)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288557(Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid ben...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288536(2-Acridin-9-yl-2-benzo[1,3]dioxol-5-yl-acetamide |...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288541(Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid 4-m...)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288536(2-Acridin-9-yl-2-benzo[1,3]dioxol-5-yl-acetamide |...)
Affinity DataIC50:  8.50E+3nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288539(Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid ben...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288548(2-Acridin-9-yl-2-benzo[1,3]dioxol-5-yl-ethanol | C...)
Affinity DataIC50:  1.00E+4nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288550(Benzo[1,3]dioxol-5-yl-(1,2,3,4-tetrahydro-acridin-...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288550(Benzo[1,3]dioxol-5-yl-(1,2,3,4-tetrahydro-acridin-...)
Affinity DataIC50:  1.20E+4nMAssay Description:Compound was tested for its ability to inhibit Endothelin A receptor induced arachidonic acid release(AARA) in rabbit renal artery vascular smooth mu...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288546(2-Benzo[1,3]dioxol-5-yl-2-(2-methyl-quinolin-4-yl)...)
Affinity DataIC50:  1.30E+4nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288543(Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetaldehyde | ...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288558(Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid 4-c...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288552(Acridin-9-yl-(4-chloro-phenyl)-acetic acid methyl ...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288556(2-Acridin-9-yl-3-benzo[1,3]dioxol-5-yl-propionic a...)
Affinity DataIC50: >2.50E+4nMAssay Description:Compound was tested for its ability to inhibit Endothelin A receptor induced arachidonic acid release(AARA) in rabbit renal artery vascular smooth mu...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288542(Benzo[1,3]dioxol-5-yl-(10-oxy-acridin-9-yl)-acetic...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288549(Benzo[1,3]dioxol-5-yl-(3,4-dimethoxy-acridin-9-yl)...)
Affinity DataIC50: >2.50E+4nMAssay Description:Compound was tested for its ability to inhibit Endothelin A receptor induced arachidonic acid release(AARA) in rabbit renal artery vascular smooth mu...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288535(Acridin-9-yl-(3,4-dichloro-phenyl)-acetic acid met...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288551(Acridin-9-yl-(3,4-dimethoxy-phenyl)-acetic acid me...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288544(Acridin-9-yl-(4-methoxy-phenyl)-acetic acid methyl...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288547(Acridin-9-yl-(2,2-dimethyl-benzo[1,3]dioxol-5-yl)-...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288554(Acridin-9-yl-(4-nitro-phenyl)-acetic acid methyl e...)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288555(Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid 4-t...)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288531(Benzo[1,3]dioxol-5-yl-(10,11-dihydro-5H-dibenzo[a,...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288534(3-Anthracen-9-yl-2-benzo[1,3]dioxol-5-yl-propionic...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288558(Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid 4-c...)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288544(Acridin-9-yl-(4-methoxy-phenyl)-acetic acid methyl...)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288533(2-Benzo[1,3]dioxol-5-yl-3,3-diphenyl-propionic aci...)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288553(Benzo[1,3]dioxol-5-yl-(2-phenyl-quinolin-4-yl)-ace...)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288540(9-Benzo[1,3]dioxol-5-ylmethyl-acridine | CHEMBL999...)
Affinity DataIC50: >2.50E+4nMAssay Description:Compound was tested for its ability to inhibit Endothelin A receptor induced arachidonic acid release(AARA) in rabbit renal artery vascular smooth mu...More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288547(Acridin-9-yl-(2,2-dimethyl-benzo[1,3]dioxol-5-yl)-...)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288556(2-Acridin-9-yl-3-benzo[1,3]dioxol-5-yl-propionic a...)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288542(Benzo[1,3]dioxol-5-yl-(10-oxy-acridin-9-yl)-acetic...)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288555(Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid 4-t...)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288533(2-Benzo[1,3]dioxol-5-yl-3,3-diphenyl-propionic aci...)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288552(Acridin-9-yl-(4-chloro-phenyl)-acetic acid methyl ...)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288540(9-Benzo[1,3]dioxol-5-ylmethyl-acridine | CHEMBL999...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288531(Benzo[1,3]dioxol-5-yl-(10,11-dihydro-5H-dibenzo[a,...)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288535(Acridin-9-yl-(3,4-dichloro-phenyl)-acetic acid met...)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288551(Acridin-9-yl-(3,4-dimethoxy-phenyl)-acetic acid me...)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288553(Benzo[1,3]dioxol-5-yl-(2-phenyl-quinolin-4-yl)-ace...)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article
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