Compile Data Set for Download or QSAR
maximum 50k data
Found 41 Enz. Inhib. hit(s) with all data for entry = 50029906
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50000040(((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl...)
Affinity DataIC50:  0.330nMAssay Description:Binding affinity against Neurokinin 1(NK1) receptor from human IM-9 cells using [I]-Bolton Hunter labeled SPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50071484(CHEMBL308148 | N-[(R)-4-(4-Acetylamino-4-phenyl-pi...)
Affinity DataIC50:  0.440nMAssay Description:Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKAMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50175494(1-{2-[(R)-3-(3,4-Dichloro-phenyl)-1-(3,4,5-trimeth...)
Affinity DataIC50:  3.10nMAssay Description:Binding affinity against Neurokinin 1(NK1) receptor from human IM-9 cells using [I]-Bolton Hunter labeled SPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289182(1-{2-[1-(3,5-Dibromo-4-methoxy-benzoyl)-3-(3,4-dic...)
Affinity DataIC50:  4nMAssay Description:Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKAMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50175494(1-{2-[(R)-3-(3,4-Dichloro-phenyl)-1-(3,4,5-trimeth...)
Affinity DataIC50:  6.20nMAssay Description:Binding affinity against Neurokinin 1(NK1) receptor from human IM-9 cells using [I]-Bolton Hunter labeled SPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289180(1-{2-[3-(3,4-Dichloro-phenyl)-1-(4-methoxy-3,5-dim...)
Affinity DataIC50:  6.90nMAssay Description:Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKAMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50175505(1-{2-[1-Benzoyl-3-((S)-3,4-dichloro-phenyl)-pyrrol...)
Affinity DataIC50:  7nMAssay Description:Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKAMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50175494(1-{2-[(R)-3-(3,4-Dichloro-phenyl)-1-(3,4,5-trimeth...)
Affinity DataIC50:  8.40nMAssay Description:Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKAMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289181(1-{2-[3-(3,4-Dichloro-phenyl)-1-(4-methoxy-benzoyl...)
Affinity DataIC50:  12nMAssay Description:Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKAMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289184(1-{2-[3-(3,4-Dichloro-phenyl)-1-(3-methoxy-benzoyl...)
Affinity DataIC50:  12nMAssay Description:Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKAMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289191(1-{2-[3-(3,4-Dichloro-phenyl)-1-(3,5-dimethoxy-4-m...)
Affinity DataIC50:  13nMAssay Description:Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKAMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289186(1-{2-[3-(3,4-Dichloro-phenyl)-1-(2-methoxy-benzoyl...)
Affinity DataIC50:  17nMAssay Description:Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKAMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289192(1-{2-[3-(3,4-Dichloro-phenyl)-1-(3,5-dimethoxy-ben...)
Affinity DataIC50:  19nMAssay Description:Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKAMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50175494(1-{2-[(R)-3-(3,4-Dichloro-phenyl)-1-(3,4,5-trimeth...)
Affinity DataIC50:  19nMAssay Description:Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKAMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50175494(1-{2-[(R)-3-(3,4-Dichloro-phenyl)-1-(3,4,5-trimeth...)
Affinity DataIC50:  21nMAssay Description:NK3 IC50 determined using [125I]-Bolton Hunter labeled eledoisin at NK3 receptors from guinea pig cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289185(1-{2-[3-(3,4-Dichloro-phenyl)-1-(2,6-dimethoxy-ben...)
Affinity DataIC50:  23nMAssay Description:Binding affinity against Neurokinin 1(NK1) receptor from human IM-9 cells using [I]-Bolton Hunter labeled SPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289187(1-{2-[3-(3,4-Dichloro-phenyl)-1-(2,4-dimethoxy-ben...)
Affinity DataIC50:  34nMAssay Description:Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKAMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289193(1-{2-[3-(3,4-Dichloro-phenyl)-1-(4-isopropoxy-3,5-...)
Affinity DataIC50:  42nMAssay Description:Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKAMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289183(1-(2-{3-(3,4-Dichloro-phenyl)-1-[2-(2-methoxy-phen...)
Affinity DataIC50:  48nMAssay Description:Binding affinity against Neurokinin 1(NK1) receptor from human IM-9 cells using [I]-Bolton Hunter labeled SPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289185(1-{2-[3-(3,4-Dichloro-phenyl)-1-(2,6-dimethoxy-ben...)
Affinity DataIC50:  53nMAssay Description:Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKAMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289189(1-(2-{3-(3,4-Dichloro-phenyl)-1-[2-(3,4,5-trimetho...)
Affinity DataIC50:  56nMAssay Description:Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKAMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289191(1-{2-[3-(3,4-Dichloro-phenyl)-1-(3,5-dimethoxy-4-m...)
Affinity DataIC50:  64nMAssay Description:Binding affinity against Neurokinin 1(NK1) receptor from human IM-9 cells using [I]-Bolton Hunter labeled SPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289189(1-(2-{3-(3,4-Dichloro-phenyl)-1-[2-(3,4,5-trimetho...)
Affinity DataIC50:  66nMAssay Description:Binding affinity against Neurokinin 1(NK1) receptor from human IM-9 cells using [I]-Bolton Hunter labeled SPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289193(1-{2-[3-(3,4-Dichloro-phenyl)-1-(4-isopropoxy-3,5-...)
Affinity DataIC50:  66nMAssay Description:Binding affinity against Neurokinin 1(NK1) receptor from human IM-9 cells using [I]-Bolton Hunter labeled SPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289192(1-{2-[3-(3,4-Dichloro-phenyl)-1-(3,5-dimethoxy-ben...)
Affinity DataIC50:  70nMAssay Description:Binding affinity against Neurokinin 1(NK1) receptor from human IM-9 cells using [I]-Bolton Hunter labeled SPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289183(1-(2-{3-(3,4-Dichloro-phenyl)-1-[2-(2-methoxy-phen...)
Affinity DataIC50:  74nMAssay Description:Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKAMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289186(1-{2-[3-(3,4-Dichloro-phenyl)-1-(2-methoxy-benzoyl...)
Affinity DataIC50:  74nMAssay Description:Binding affinity against Neurokinin 1(NK1) receptor from human IM-9 cells using [I]-Bolton Hunter labeled SPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289188(CHEMBL176860 | Carbonic acid 4-[3-[2-(4-carbamoyl-...)
Affinity DataIC50:  96nMAssay Description:Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKAMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289184(1-{2-[3-(3,4-Dichloro-phenyl)-1-(3-methoxy-benzoyl...)
Affinity DataIC50:  107nMAssay Description:Binding affinity against Neurokinin 1(NK1) receptor from human IM-9 cells using [I]-Bolton Hunter labeled SPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289187(1-{2-[3-(3,4-Dichloro-phenyl)-1-(2,4-dimethoxy-ben...)
Affinity DataIC50:  127nMAssay Description:Binding affinity against Neurokinin 1(NK1) receptor from human IM-9 cells using [I]-Bolton Hunter labeled SPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289190(1-(2-{3-(3,4-Dichloro-phenyl)-1-[2-(3-isopropoxy-p...)
Affinity DataIC50:  138nMAssay Description:Binding affinity against Neurokinin 1(NK1) receptor from human IM-9 cells using [I]-Bolton Hunter labeled SPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289180(1-{2-[3-(3,4-Dichloro-phenyl)-1-(4-methoxy-3,5-dim...)
Affinity DataIC50:  168nMAssay Description:Binding affinity against Neurokinin 1(NK1) receptor from human IM-9 cells using [I]-Bolton Hunter labeled SPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50071484(CHEMBL308148 | N-[(R)-4-(4-Acetylamino-4-phenyl-pi...)
Affinity DataIC50:  208nMAssay Description:NK3 IC50 determined using [125I]-Bolton Hunter labeled eledoisin at NK3 receptors from guinea pig cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289188(CHEMBL176860 | Carbonic acid 4-[3-[2-(4-carbamoyl-...)
Affinity DataIC50:  252nMAssay Description:Binding affinity against Neurokinin 1(NK1) receptor from human IM-9 cells using [I]-Bolton Hunter labeled SPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50175505(1-{2-[1-Benzoyl-3-((S)-3,4-dichloro-phenyl)-pyrrol...)
Affinity DataIC50:  271nMAssay Description:Binding affinity against Neurokinin 1(NK1) receptor from human IM-9 cells using [I]-Bolton Hunter labeled SPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289182(1-{2-[1-(3,5-Dibromo-4-methoxy-benzoyl)-3-(3,4-dic...)
Affinity DataIC50:  313nMAssay Description:Binding affinity against Neurokinin 1(NK1) receptor from human IM-9 cells using [I]-Bolton Hunter labeled SPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289190(1-(2-{3-(3,4-Dichloro-phenyl)-1-[2-(3-isopropoxy-p...)
Affinity DataIC50:  548nMAssay Description:Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKAMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50071484(CHEMBL308148 | N-[(R)-4-(4-Acetylamino-4-phenyl-pi...)
Affinity DataIC50:  593nMAssay Description:Binding affinity against Neurokinin 1(NK1) receptor from human IM-9 cells using [I]-Bolton Hunter labeled SPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289181(1-{2-[3-(3,4-Dichloro-phenyl)-1-(4-methoxy-benzoyl...)
Affinity DataIC50:  634nMAssay Description:Binding affinity against Neurokinin 1(NK1) receptor from human IM-9 cells using [I]-Bolton Hunter labeled SPMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-K receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50000040(((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKAMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50000040(((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:NK3 IC50 determined using [125I]-Bolton Hunter labeled eledoisin at NK3 receptors from guinea pig cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article