BindingDB logo
myBDB logout

Articleid 50029950

Compile data set for download or QSAR
Found 22 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aldose reductase


(Sus scrofa)
BDBM50289610
PNG
(CHEMBL44717 | [3-(4,5,7-Trifluoro-benzothiazol-2-y...)
Show SMILES OC(=O)Cc1cccc(Cc2nc3c(F)c(F)cc(F)c3s2)c1
Show InChI InChI=1S/C16H10F3NO2S/c17-10-7-11(18)16-15(14(10)19)20-12(23-16)5-8-2-1-3-9(4-8)6-13(21)22/h1-4,7H,5-6H2,(H,21,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 6.60n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
Aldose reductase


(Sus scrofa)
BDBM50289614
PNG
(CHEMBL288748 | [3-Chloro-5-(4,5,7-trifluoro-benzot...)
Show SMILES OC(=O)Cc1cc(Cl)cc(Cc2nc3c(F)c(F)cc(F)c3s2)c1
Show InChI InChI=1S/C16H9ClF3NO2S/c17-9-2-7(1-8(3-9)5-13(22)23)4-12-21-15-14(20)10(18)6-11(19)16(15)24-12/h1-3,6H,4-5H2,(H,22,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 7n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
Aldose reductase


(Sus scrofa)
BDBM50289613
PNG
(CHEMBL44743 | {Phenyl-[3-(4,5,7-trifluoro-benzothi...)
Show SMILES OC(=O)CN(C(=O)CCc1nc2c(F)c(F)cc(F)c2s1)c1ccccc1
Show InChI InChI=1S/C18H13F3N2O3S/c19-11-8-12(20)18-17(16(11)21)22-13(27-18)6-7-14(24)23(9-15(25)26)10-4-2-1-3-5-10/h1-5,8H,6-7,9H2,(H,25,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 8.30n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
Aldose reductase


(Sus scrofa)
BDBM50289624
PNG
(CHEMBL44780 | {Phenyl-[3-(4,5,7-trifluoro-benzothi...)
Show SMILES OC(=O)CN(C(=S)CCc1nc2c(F)c(F)cc(F)c2s1)c1ccccc1
Show InChI InChI=1S/C18H13F3N2O2S2/c19-11-8-12(20)18-17(16(11)21)22-13(27-18)6-7-14(26)23(9-15(24)25)10-4-2-1-3-5-10/h1-5,8H,6-7,9H2,(H,24,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 8.40n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
Aldose reductase


(Sus scrofa)
BDBM50289628
PNG
(3-Carboxymethyl-5-(4,5,7-trifluoro-benzothiazol-2-...)
Show SMILES OC(=O)Cc1cc(Cc2nc3c(F)c(F)cc(F)c3s2)cc(c1)C(O)=O
Show InChI InChI=1S/C17H10F3NO4S/c18-10-6-11(19)16-15(14(10)20)21-12(26-16)4-7-1-8(5-13(22)23)3-9(2-7)17(24)25/h1-3,6H,4-5H2,(H,22,23)(H,24,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 8.70n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
Aldose reductase


(Sus scrofa)
BDBM50289617
PNG
(CHEMBL47614 | [3-Fluoro-5-(4,5,7-trifluoro-benzoth...)
Show SMILES OC(=O)Cc1cc(F)cc(Cc2nc3c(F)c(F)cc(F)c3s2)c1
Show InChI InChI=1S/C16H9F4NO2S/c17-9-2-7(1-8(3-9)5-13(22)23)4-12-21-15-14(20)10(18)6-11(19)16(15)24-12/h1-3,6H,4-5H2,(H,22,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 8.80n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
Aldose reductase


(Sus scrofa)
BDBM50289616
PNG
(CHEMBL45751 | [2-Chloro-3-(4,5,7-trifluoro-benzoth...)
Show SMILES OC(=O)Cc1cccc(Cc2nc3c(F)c(F)cc(F)c3s2)c1Cl
Show InChI InChI=1S/C16H9ClF3NO2S/c17-13-7(2-1-3-8(13)5-12(22)23)4-11-21-15-14(20)9(18)6-10(19)16(15)24-11/h1-3,6H,4-5H2,(H,22,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 9.30n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
Aldose reductase


(Sus scrofa)
BDBM50289621
PNG
(CHEMBL46074 | [3-Bromo-5-(4,5,7-trifluoro-benzothi...)
Show SMILES OC(=O)Cc1cc(Br)cc(Cc2nc3c(F)c(F)cc(F)c3s2)c1
Show InChI InChI=1S/C16H9BrF3NO2S/c17-9-2-7(1-8(3-9)5-13(22)23)4-12-21-15-14(20)10(18)6-11(19)16(15)24-12/h1-3,6H,4-5H2,(H,22,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 9.40n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
Aldose reductase


(Sus scrofa)
BDBM50289629
PNG
(CHEMBL47646 | [3-Oxo-4-(4,5,7-trifluoro-benzothiaz...)
Show SMILES OC(=O)CC1Sc2ccccc2N(Cc2nc3c(F)c(F)cc(F)c3s2)C1=O
Show InChI InChI=1S/C18H11F3N2O3S2/c19-8-5-9(20)17-16(15(8)21)22-13(28-17)7-23-10-3-1-2-4-11(10)27-12(18(23)26)6-14(24)25/h1-5,12H,6-7H2,(H,24,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
n/an/a 9.5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
Aldose reductase


(Sus scrofa)
BDBM50289612
PNG
(CHEMBL46170 | [3-Methyl-5-(4,5,7-trifluoro-benzoth...)
Show SMILES Cc1cc(CC(O)=O)cc(Cc2nc3c(F)c(F)cc(F)c3s2)c1
Show InChI InChI=1S/C17H12F3NO2S/c1-8-2-9(4-10(3-8)6-14(22)23)5-13-21-16-15(20)11(18)7-12(19)17(16)24-13/h2-4,7H,5-6H2,1H3,(H,22,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 9.60n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
Aldose reductase


(Sus scrofa)
BDBM50289625
PNG
(CHEMBL43995 | {Benzyl-[3-(4,5,7-trifluoro-benzothi...)
Show SMILES OC(=O)CN(Cc1ccccc1)C(=O)CCc1nc2c(F)c(F)cc(F)c2s1
Show InChI InChI=1S/C19H15F3N2O3S/c20-12-8-13(21)19-18(17(12)22)23-14(28-19)6-7-15(25)24(10-16(26)27)9-11-4-2-1-3-5-11/h1-5,8H,6-7,9-10H2,(H,26,27)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 9.70n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
Aldose reductase


(Sus scrofa)
BDBM50289620
PNG
(CHEMBL442690 | {Methyl-[3-(4,5,7-trifluoro-benzoth...)
Show SMILES CN(CC(O)=O)C(=S)CCc1nc2c(F)c(F)cc(F)c2s1
Show InChI InChI=1S/C13H11F3N2O2S2/c1-18(5-10(19)20)9(21)3-2-8-17-12-11(16)6(14)4-7(15)13(12)22-8/h4H,2-3,5H2,1H3,(H,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 11n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
Aldose reductase


(Sus scrofa)
BDBM50289615
PNG
(CHEMBL45290 | [3-Iodo-5-(4,5,7-trifluoro-benzothia...)
Show SMILES OC(=O)Cc1cc(I)cc(Cc2nc3c(F)c(F)cc(F)c3s2)c1
Show InChI InChI=1S/C16H9F3INO2S/c17-10-6-11(18)16-15(14(10)19)21-12(24-16)4-7-1-8(5-13(22)23)3-9(20)2-7/h1-3,6H,4-5H2,(H,22,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 11n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
Aldose reductase


(Sus scrofa)
BDBM50289619
PNG
(CHEMBL542104 | [3-Dimethylamino-5-(4,5,7-trifluoro...)
Show SMILES CN(C)c1cc(CC(O)=O)cc(Cc2nc3c(F)c(F)cc(F)c3s2)c1
Show InChI InChI=1S/C18H15F3N2O2S/c1-23(2)11-4-9(3-10(5-11)7-15(24)25)6-14-22-17-16(21)12(19)8-13(20)18(17)26-14/h3-5,8H,6-7H2,1-2H3,(H,24,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 12n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
Aldose reductase


(Sus scrofa)
BDBM16496
PNG
(2-{3-[(4-bromo-2-fluorophenyl)methyl]-7-chloro-2,4...)
Show SMILES OC(=O)Cn1c2cc(Cl)ccc2c(=O)n(Cc2ccc(Br)cc2F)c1=O
Show InChI InChI=1S/C17H11BrClFN2O4/c18-10-2-1-9(13(20)5-10)7-22-16(25)12-4-3-11(19)6-14(12)21(17(22)26)8-15(23)24/h1-6H,7-8H2,(H,23,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents

PDB
Article
n/an/a 12n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Aldose reductase


(Sus scrofa)
BDBM50289623
PNG
(CHEMBL296769 | {Methyl-[3-(4,5,7-trifluoro-benzoth...)
Show SMILES CN(CC(O)=O)C(=O)CCc1nc2c(F)c(F)cc(F)c2s1
Show InChI InChI=1S/C13H11F3N2O3S/c1-18(5-10(20)21)9(19)3-2-8-17-12-11(16)6(14)4-7(15)13(12)22-8/h4H,2-3,5H2,1H3,(H,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 13n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
Aldose reductase


(Sus scrofa)
BDBM16314
PNG
(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)
Show SMILES COc1ccc2c(cccc2c1C(F)(F)F)C(=S)N(C)CC(O)=O
Show InChI InChI=1S/C16H14F3NO3S/c1-20(8-13(21)22)15(24)11-5-3-4-10-9(11)6-7-12(23-2)14(10)16(17,18)19/h3-7H,8H2,1-2H3,(H,21,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

DrugBank
PDB
Article
n/an/a 16n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Aldose reductase


(Sus scrofa)
BDBM50289626
PNG
(CHEMBL297861 | [2-(4,5,7-Trifluoro-benzothiazol-2-...)
Show SMILES OC(=O)Cc1ccccc1Cc1nc2c(F)c(F)cc(F)c2s1
Show InChI InChI=1S/C16H10F3NO2S/c17-10-7-11(18)16-15(14(10)19)20-12(23-16)5-8-3-1-2-4-9(8)6-13(21)22/h1-4,7H,5-6H2,(H,21,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 19n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
Aldose reductase


(Sus scrofa)
BDBM50289611
PNG
(CHEMBL45352 | {Phenethyl-[3-(4,5,7-trifluoro-benzo...)
Show SMILES OC(=O)CN(CCc1ccccc1)C(=O)CCc1nc2c(F)c(F)cc(F)c2s1
Show InChI InChI=1S/C20H17F3N2O3S/c21-13-10-14(22)20-19(18(13)23)24-15(29-20)6-7-16(26)25(11-17(27)28)9-8-12-4-2-1-3-5-12/h1-5,10H,6-9,11H2,(H,27,28)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 21n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
Aldose reductase


(Sus scrofa)
BDBM50289622
PNG
(CHEMBL44941 | {Benzyl-[3-(4,5,7-trifluoro-benzothi...)
Show SMILES OC(=O)CN(Cc1ccccc1)C(=S)CCc1nc2c(F)c(F)cc(F)c2s1
Show InChI InChI=1S/C19H15F3N2O2S2/c20-12-8-13(21)19-18(17(12)22)23-14(28-19)6-7-15(27)24(10-16(25)26)9-11-4-2-1-3-5-11/h1-5,8H,6-7,9-10H2,(H,25,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 23n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
Aldose reductase


(Sus scrofa)
BDBM50289618
PNG
(CHEMBL296780 | [4-(4,5,7-Trifluoro-benzothiazol-2-...)
Show SMILES OC(=O)Cc1ccc(Cc2nc3c(F)c(F)cc(F)c3s2)cc1
Show InChI InChI=1S/C16H10F3NO2S/c17-10-7-11(18)16-15(14(10)19)20-12(23-16)5-8-1-3-9(4-2-8)6-13(21)22/h1-4,7H,5-6H2,(H,21,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 38n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
Aldose reductase


(Sus scrofa)
BDBM50289627
PNG
(6-(4,5,7-Trifluoro-benzothiazol-2-yl)-hexanoic aci...)
Show SMILES OC(=O)CCCCCc1nc2c(F)c(F)cc(F)c2s1
Show InChI InChI=1S/C13H12F3NO2S/c14-7-6-8(15)13-12(11(7)16)17-9(20-13)4-2-1-3-5-10(18)19/h6H,1-5H2,(H,18,19)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
n/an/a 50n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against porcine lens aldose reductase (AR) with DL-glyceraldehyde as the substrate


Bioorg Med Chem Lett 7: 1677-1682 (1997)


Article DOI: 10.1016/S0960-894X(97)00287-4
BindingDB Entry DOI: 10.7270/Q2M61K7T
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%