Compile Data Set for Download or QSAR
maximum 50k data
Found 47 Enz. Inhib. hit(s) with all data for entry = 50030136
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291482(2-[2-(2,4,6-Trimethyl-phenyl)-vinyl]-thiophene-3-s...)
Affinity DataIC50:  44nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291503(2-[2-(2,4,6-Trimethyl-phenyl)-ethyl]-thiophene-3-s...)
Affinity DataIC50:  46nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291490(3-[2-(2,4,6-Trimethyl-phenyl)-vinyl]-thiophene-2-s...)
Affinity DataIC50:  53nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291499(2-[2-(2,4-Dimethyl-phenyl)-ethyl]-thiophene-3-sulf...)
Affinity DataIC50:  55nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291489(3-[2-(2,4,6-Trimethyl-phenyl)-ethyl]-thiophene-2-s...)
Affinity DataIC50:  58nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291486(2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-ethyl]-thiop...)
Affinity DataIC50:  62nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291491(3-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-vinyl]-thiop...)
Affinity DataIC50:  72nMAssay Description:Tested for the inhibitory activity of cloned human ETA receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291498(3-{2-[6-(Tetrahydro-pyran-4-yloxymethyl)-benzo[1,3...)
Affinity DataIC50:  73nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291484(3-[2-(6-Hydroxymethyl-benzo[1,3]dioxol-5-yl)-vinyl...)
Affinity DataIC50:  79nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291488(2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-vinyl]-thiop...)
Affinity DataIC50:  81nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291500(3-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-ethyl]-thiop...)
Affinity DataIC50:  91nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291496(3-[2-(2,4-Dimethyl-phenyl)-ethyl]-thiophene-2-sulf...)
Affinity DataIC50:  102nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291501(2-(2-p-Tolyl-ethyl)-thiophene-3-sulfonic acid (4-b...)
Affinity DataIC50:  106nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291492(2-(2-Benzo[1,3]dioxol-5-yl-vinyl)-thiophene-3-sulf...)
Affinity DataIC50:  141nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291483(2-[2-(2,4-Dimethyl-phenyl)-vinyl]-thiophene-3-sulf...)
Affinity DataIC50:  166nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291495(3-[2-(2,4-Dimethyl-phenyl)-vinyl]-thiophene-2-sulf...)
Affinity DataIC50:  180nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291485(2-(2-Benzo[1,3]dioxol-5-yl-ethyl)-thiophene-3-sulf...)
Affinity DataIC50:  205nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291502(3-(2-Benzo[1,3]dioxol-5-yl-vinyl)-thiophene-2-sulf...)
Affinity DataIC50:  218nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291493(2-(2-p-Tolyl-vinyl)-thiophene-3-sulfonic acid (4-b...)
Affinity DataIC50:  231nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291487(3-(2-Benzo[1,3]dioxol-5-yl-ethyl)-thiophene-2-sulf...)
Affinity DataIC50:  237nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291494(3-(2-p-Tolyl-ethyl)-thiophene-2-sulfonic acid (4-b...)
Affinity DataIC50:  347nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50098772(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50:  630nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291497(3-(2-p-Tolyl-vinyl)-thiophene-2-sulfonic acid (4-b...)
Affinity DataIC50:  936nMAssay Description:Tested for its activity in cloned human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291489(3-[2-(2,4,6-Trimethyl-phenyl)-ethyl]-thiophene-2-s...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291490(3-[2-(2,4,6-Trimethyl-phenyl)-vinyl]-thiophene-2-s...)
Affinity DataIC50:  1.72E+3nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291482(2-[2-(2,4,6-Trimethyl-phenyl)-vinyl]-thiophene-3-s...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291503(2-[2-(2,4,6-Trimethyl-phenyl)-ethyl]-thiophene-3-s...)
Affinity DataIC50:  2.09E+3nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291483(2-[2-(2,4-Dimethyl-phenyl)-vinyl]-thiophene-3-sulf...)
Affinity DataIC50:  2.97E+3nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291495(3-[2-(2,4-Dimethyl-phenyl)-vinyl]-thiophene-2-sulf...)
Affinity DataIC50:  2.97E+3nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291484(3-[2-(6-Hydroxymethyl-benzo[1,3]dioxol-5-yl)-vinyl...)
Affinity DataIC50:  3.24E+3nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291488(2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-vinyl]-thiop...)
Affinity DataIC50:  3.28E+3nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291499(2-[2-(2,4-Dimethyl-phenyl)-ethyl]-thiophene-3-sulf...)
Affinity DataIC50:  3.48E+3nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291493(2-(2-p-Tolyl-vinyl)-thiophene-3-sulfonic acid (4-b...)
Affinity DataIC50:  4.13E+3nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291498(3-{2-[6-(Tetrahydro-pyran-4-yloxymethyl)-benzo[1,3...)
Affinity DataIC50:  4.14E+3nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291496(3-[2-(2,4-Dimethyl-phenyl)-ethyl]-thiophene-2-sulf...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291492(2-(2-Benzo[1,3]dioxol-5-yl-vinyl)-thiophene-3-sulf...)
Affinity DataIC50:  5.25E+3nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291491(3-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-vinyl]-thiop...)
Affinity DataIC50:  5.37E+3nMAssay Description:Tested for the inhibitory activity of cloned human ETB receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291497(3-(2-p-Tolyl-vinyl)-thiophene-2-sulfonic acid (4-b...)
Affinity DataIC50:  6.64E+3nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291486(2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-ethyl]-thiop...)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289945(3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thioph...)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291485(2-(2-Benzo[1,3]dioxol-5-yl-ethyl)-thiophene-3-sulf...)
Affinity DataIC50:  9.24E+3nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291494(3-(2-p-Tolyl-ethyl)-thiophene-2-sulfonic acid (4-b...)
Affinity DataIC50:  9.36E+3nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291502(3-(2-Benzo[1,3]dioxol-5-yl-vinyl)-thiophene-2-sulf...)
Affinity DataIC50:  9.96E+3nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291501(2-(2-p-Tolyl-ethyl)-thiophene-3-sulfonic acid (4-b...)
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291500(3-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-ethyl]-thiop...)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin receptor type B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291487(3-(2-Benzo[1,3]dioxol-5-yl-ethyl)-thiophene-2-sulf...)
Affinity DataIC50:  1.79E+4nMAssay Description:Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291481(2-(2,4,6-Trimethyl-phenoxymethyl)-thiophene-3-sulf...)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In DepthDetails Article