BindingDB logo
myBDB logout

Articleid 50030165

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (human))
BDBM7463
PNG
(4,5-diphenyl-1H-pyrazolo[3,4-c]pyridazin-3-amine |...)
Show SMILES Nc1n[nH]c2nnc(-c3ccccc3)c(-c3ccccc3)c12
Show InChI InChI=1S/C17H13N5/c18-16-14-13(11-7-3-1-4-8-11)15(12-9-5-2-6-10-12)19-21-17(14)22-20-16/h1-10H,(H3,18,20,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a>5.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against KDR


J Med Chem 48: 6843-6854 (2005)


Article DOI: 10.1021/jm058013g
BindingDB Entry DOI: 10.7270/Q2TX3FCT
More data for this
Ligand-Target Pair
SRC


(Homo sapiens (human))
BDBM7463
PNG
(4,5-diphenyl-1H-pyrazolo[3,4-c]pyridazin-3-amine |...)
Show SMILES Nc1n[nH]c2nnc(-c3ccccc3)c(-c3ccccc3)c12
Show InChI InChI=1S/C17H13N5/c18-16-14-13(11-7-3-1-4-8-11)15(12-9-5-2-6-10-12)19-21-17(14)22-20-16/h1-10H,(H3,18,20,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a>5.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against protein tyrosine kinase Lck


J Med Chem 48: 6843-6854 (2005)


Article DOI: 10.1021/jm058013g
BindingDB Entry DOI: 10.7270/Q2TX3FCT
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%