Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 50041088
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  9.60nMAssay Description:Ability to inhibit Lactobacillus casei dihydrofolate reductase in vitro was determinedMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  9.60nMAssay Description:Ability to inhibit Lactobacillus casei dihydrofolate reductase in vitro was determinedMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50028366(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethylsulfanyl]...)
Affinity DataIC50:  400nMAssay Description:Ability to inhibit Lactobacillus casei dihydrofolate reductase in vitro was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028366(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethylsulfanyl]...)
Affinity DataIC50:  400nMAssay Description:Ability to inhibit Lactobacillus casei dihydrofolate reductase in vitro was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028368(2-[4-(2,4-Diamino-pteridin-6-ylmethylsulfanyl)-ben...)
Affinity DataIC50:  2.70E+3nMAssay Description:Ability to inhibit human HeLa cell dihydrofolate reductase in vitro was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  4.00E+4nMAssay Description:Ability to inhibit Lactobacillus casei thymidylate synthase in vitro was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50028366(2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethylsulfanyl]...)
Affinity DataIC50:  6.00E+4nMAssay Description:Ability to inhibit Lactobacillus casei thymidylate synthase in vitro was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50028369(2-[4-(2,4-Diamino-pteridin-6-ylmethoxy)-benzoylami...)
Affinity DataIC50:  7.40E+8nMAssay Description:Ability to inhibit human HeLa cell dihydrofolate reductase in vitro was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed