Compile Data Set for Download or QSAR
maximum 50k data
Found 62 Enz. Inhib. hit(s) with all data for entry = 50004906
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50002660(((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl...)
Affinity DataIC50:  0.0850nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029878((2R,3S)-2-Benzhydryl-3-(3,5-bis-trifluoromethyl-be...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029884((2S,3S)-2-Benzhydryl-3-(3,5-bis-trifluoromethyl-be...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029847(2-Benzhydryl-3-(3-iodo-5-methyl-benzyloxy)-1-aza-b...)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50000040(((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029871(2-Benzhydryl-3-(3,5-dimethyl-benzyloxy)-1-aza-bicy...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029869(2-Benzhydryl-3-(3-methyl-5-trimethylsilanyl-benzyl...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029871(2-Benzhydryl-3-(3,5-dimethyl-benzyloxy)-1-aza-bicy...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029879(2-Benzhydryl-3-(3-methoxy-5-methyl-benzyloxy)-1-az...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029879(2-Benzhydryl-3-(3-methoxy-5-methyl-benzyloxy)-1-az...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029839(2-Benzhydryl-3-(3,5-bis-trifluoromethyl-benzyloxy)...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029839(2-Benzhydryl-3-(3,5-bis-trifluoromethyl-benzyloxy)...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029850(3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-(1,2-diphe...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029876(3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-(cyclohexy...)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029875(2-Benzhydryl-3-(3,5-dimethoxy-benzyloxy)-1-aza-bic...)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029875(2-Benzhydryl-3-(3,5-dimethoxy-benzyloxy)-1-aza-bic...)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029845(2-Benzhydryl-3-(3,5-dichloro-benzyloxy)-1-aza-bicy...)
Affinity DataIC50:  9nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029845(2-Benzhydryl-3-(3,5-dichloro-benzyloxy)-1-aza-bicy...)
Affinity DataIC50:  9nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029872(2-Benzhydryl-3-(3-methyl-benzyloxy)-1-aza-bicyclo[...)
Affinity DataIC50:  20nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029842(2-Benzhydryl-3-(3,5-difluoro-benzyloxy)-1-aza-bicy...)
Affinity DataIC50:  33nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029863(2-Benzhydryl-3-(2,5-dimethyl-benzyloxy)-1-aza-bicy...)
Affinity DataIC50:  36nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029880(2-Benzhydryl-3-(2-bromo-benzyloxy)-1-aza-bicyclo[2...)
Affinity DataIC50:  37nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029857(2-Benzhydryl-3-(3-fluoro-benzyloxy)-1-aza-bicyclo[...)
Affinity DataIC50:  37nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029874(2-Benzhydryl-3-(3-methoxy-benzyloxy)-1-aza-bicyclo...)
Affinity DataIC50:  56nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029882(2-Benzhydryl-3-(3-phenoxy-benzyloxy)-1-aza-bicyclo...)
Affinity DataIC50:  62nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029846(2-Benzhydryl-3-(3-chloro-benzyloxy)-1-aza-bicyclo[...)
Affinity DataIC50:  62nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029877(2-Benzhydryl-3-(2-trifluoromethyl-benzyloxy)-1-aza...)
Affinity DataIC50:  67nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029860(2-Benzhydryl-3-(2-chloro-benzyloxy)-1-aza-bicyclo[...)
Affinity DataIC50:  80nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029887(2-(2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yloxymet...)
Affinity DataIC50:  86nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029856(2-Benzhydryl-3-(2-fluoro-benzyloxy)-1-aza-bicyclo[...)
Affinity DataIC50:  93nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029891(2-Benzyl-3-(3,5-bis-trifluoromethyl-benzyloxy)-1-a...)
Affinity DataIC50:  103nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029870(2-Benzhydryl-3-(2,5-difluoro-benzyloxy)-1-aza-bicy...)
Affinity DataIC50:  106nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029865(2-Benzyl-3-(3,5-dimethyl-benzyloxy)-1-aza-bicyclo[...)
Affinity DataIC50:  107nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029864(2-Benzhydryl-3-benzyloxy-1-aza-bicyclo[2.2.2]octan...)
Affinity DataIC50:  110nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50284614(2-Benzylidene-3-(3,5-dimethyl-benzyloxy)-1-aza-bic...)
Affinity DataIC50:  120nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029855((2S,3R)-2-Benzhydryl-3-(3,5-bis-trifluoromethyl-be...)
Affinity DataIC50:  125nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029883(3-(2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yloxymet...)
Affinity DataIC50:  127nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029853(2-Benzhydryl-3-(2-methyl-benzyloxy)-1-aza-bicyclo[...)
Affinity DataIC50:  150nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029854(2-Benzhydryl-3-(3,4-dimethyl-benzyloxy)-1-aza-bicy...)
Affinity DataIC50:  172nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029873(2-Benzhydryl-3-(3-nitro-benzyloxy)-1-aza-bicyclo[2...)
Affinity DataIC50:  197nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029844(2-Benzhydryl-3-(4-methyl-benzyloxy)-1-aza-bicyclo[...)
Affinity DataIC50:  246nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029867(2-Benzhydryl-3-(4-fluoro-benzyloxy)-1-aza-bicyclo[...)
Affinity DataIC50:  252nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029840(2-Benzhydryl-3-(3-trifluoromethyl-benzyloxy)-1-aza...)
Affinity DataIC50:  300nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029843((2R,3R)-2-Benzhydryl-3-(3,5-bis-trifluoromethyl-be...)
Affinity DataIC50:  300nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029852(3-(3,5-Dimethyl-benzyloxy)-2-(1,2-diphenyl-ethyl)-...)
Affinity DataIC50:  353nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029852(3-(3,5-Dimethyl-benzyloxy)-2-(1,2-diphenyl-ethyl)-...)
Affinity DataIC50:  353nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029866(2-Benzhydryl-3-(4-trifluoromethyl-benzyloxy)-1-aza...)
Affinity DataIC50:  370nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029851(2-Benzhydryl-3-(4-chloro-benzyloxy)-1-aza-bicyclo[...)
Affinity DataIC50:  417nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029850(3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-(1,2-diphe...)
Affinity DataIC50:  425nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50029881(((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl...)
Affinity DataIC50:  700nMAssay Description:Inhibition of binding of [125I]-SP to the CHO cell line expressing human Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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