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Found 32 Enz. Inhib. hit(s) with all data for entry = 50005041
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031845((4-Biphenyl-4-yl-1-phosphono-butyl)-phosphonic aci...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031839(((E)-6,10-Dimethyl-1-phosphono-undeca-5,9-dienyl)-...)
Affinity DataIC50:  1nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031843(((E)-8,12-Dimethyl-1-phosphono-trideca-7,11-dienyl...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031848(((E)-7,11-Dimethyl-1-phosphono-dodeca-6,10-dienyl)...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031844(((E)-1-Hydroxyphosphinoyl-6,10-dimethyl-undeca-5,9...)
Affinity DataIC50:  4nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031851(((E)-10,14-Dimethyl-1-phosphono-pentadeca-9,13-die...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031842(CHEMBL86867 | [(5E,9E)-1-(Hydroxy-hydroxymethyl-ph...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031847(((5E,9E)-6,10,14-Trimethyl-1-phosphono-pentadeca-5...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031859(CHEMBL314797 | [(5E,9E)-1-(Hydroxy-methoxymethyl-p...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031832(CHEMBL87922 | [(6E,10E)-1-(Hydroxy-methyl-phosphin...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031862(CHEMBL84629 | [(E)-1-(Hydroxy-methyl-phosphinoyl)-...)
Affinity DataIC50:  8.70nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031836(((8E,12E)-9,13,17-Trimethyl-1-phosphono-octadeca-8...)
Affinity DataIC50:  11.8nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031849(CHEMBL86918 | [(5E,9E)-1-(Hydroxy-methyl-phosphino...)
Affinity DataIC50:  12.9nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031837(CHEMBL87489 | [(E)-1-(Hydroxy-methoxymethyl-phosph...)
Affinity DataIC50:  13.1nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031840(CHEMBL84961 | [4-Biphenyl-4-yl-1-(hydroxy-methoxym...)
Affinity DataIC50:  14.8nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031854(((E)-9,13-Dimethyl-1-phosphono-tetradeca-8,12-dien...)
Affinity DataIC50:  17.6nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031855(CHEMBL86621 | [4-Biphenyl-4-yl-1-(hydroxy-hydroxym...)
Affinity DataIC50:  23.9nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031850(CHEMBL420416 | [(E)-1-(Hydroxy-methyl-phosphinoyl)...)
Affinity DataIC50:  30.7nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031853(((3E,7E)-4,8,12-Trimethyl-1-phosphono-trideca-3,7,...)
Affinity DataIC50:  32.4nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031846(((E)-4,8-Dimethyl-1-phosphono-nona-3,7-dienyl)-pho...)
Affinity DataIC50:  35.5nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031861(CHEMBL87822 | [(E)-1-(Hydroxy-hydroxymethyl-phosph...)
Affinity DataIC50:  38.7nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031841(((E)-5,9-Dimethyl-1-phosphono-deca-4,8-dienyl)-pho...)
Affinity DataIC50:  77.7nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031858(CHEMBL86580 | [(E)-1-(Hydroxy-methyl-phosphinoyl)-...)
Affinity DataIC50:  81nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031834(CHEMBL86919 | [(3E,7E)-1-(Hydroxy-methyl-phosphino...)
Affinity DataIC50:  106nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031838(CHEMBL315239 | [(E)-1-(Hydroxy-methyl-phosphinoyl)...)
Affinity DataIC50:  374nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031863(CHEMBL441807 | [4-Biphenyl-4-yl-1-(hydroxy-methyl-...)
Affinity DataIC50:  490nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031856(CHEMBL86707 | [(E)-1-(Hydroxy-methyl-phosphinoyl)-...)
Affinity DataIC50:  605nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031835((6E,10E)-7,11,15-Trimethyl-2-phosphono-hexadeca-6,...)
Affinity DataIC50:  880nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031833((E)-7,11-Dimethyl-2-phosphono-dodeca-6,10-dienoic ...)
Affinity DataIC50:  1.65E+3nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031857(5-Biphenyl-4-yl-2-phosphono-pentanoic acid | CHEMB...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031852((6-Methyl-1-phosphono-hept-5-enyl)-phosphonic acid...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50031860(CHEMBL86632 | [(E)-1-(Hydroxy-methyl-phosphinoyl)-...)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition rat liver microsomal squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed