Compile Data Set for Download or QSAR
maximum 50k data
Found 51 Enz. Inhib. hit(s) with all data for entry = 50005187
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033969(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  10nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033969(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  10nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033960(CHEMBL11612 | N-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-...)
Affinity DataIC50:  11nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033949(1-[5-(4,5-Dicyclohexyl-1H-imidazol-2-ylsulfanyl)-p...)
Affinity DataIC50:  20nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033950(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diisopropyl-1H-i...)
Affinity DataIC50:  20nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033966(CHEMBL11267 | N-[5-[(1H,9H-dibenzo[4,5:8,9] [1,3]d...)
Affinity DataIC50:  30nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033971(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  30nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033975(1-{5-[4,5-Bis-(3-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50:  40nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033997(1-{5-[4,5-Bis-(4-fluoro-phenyl)-1H-imidazol-2-ylsu...)
Affinity DataIC50:  40nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033998(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  40nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033955(CHEMBL11201 | N-{5-[4,5-Bis-(4-dimethylamino-pheny...)
Affinity DataIC50:  50nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033957(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  50nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033952(1-{5-[4,5-Bis-(4-dimethylamino-phenyl)-1H-imidazol...)
Affinity DataIC50:  50nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033995(3-(2,4-Difluoro-phenyl)-1-heptyl-1-[5-(1H-8-oxa-1,...)
Affinity DataIC50:  60nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033974(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-dipropyl-1H-imid...)
Affinity DataIC50:  60nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033984(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-di-thiophen-2-yl...)
Affinity DataIC50:  60nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033967(1-(2-Butoxy-ethyl)-3-(2,4-difluoro-phenyl)-1-[5-(4...)
Affinity DataIC50:  70nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033978(1-{5-[4,5-Bis-(4-methylsulfanyl-phenyl)-1H-imidazo...)
Affinity DataIC50:  70nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033953(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  70nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033964(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-di-p-tolyl-1H-im...)
Affinity DataIC50:  80nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033990(3-(2,4-Difluoro-phenyl)-1-{2-[2-(4,5-diphenyl-1H-i...)
Affinity DataIC50:  80nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033954(1-(2-Diethylamino-ethyl)-3-(2,4-difluoro-phenyl)-1...)
Affinity DataIC50:  80nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033980(1-{5-[4,5-Bis-(4-dimethylamino-phenyl)-1H-imidazol...)
Affinity DataIC50:  80nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033980(1-{5-[4,5-Bis-(4-dimethylamino-phenyl)-1H-imidazol...)
Affinity DataIC50:  80nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033948(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  90nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033982(CHEMBL11303 | {5-[4,5-Bis-(4-dimethylamino-phenyl)...)
Affinity DataIC50:  120nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033968(1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50:  140nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033981(1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50:  160nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033951(3-(2,4-Difluoro-phenyl)-1-(2-{[2-(4,5-diphenyl-1H-...)
Affinity DataIC50:  170nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033959(1-(2-Butoxy-ethyl)-1-[5-(4,5-diphenyl-1H-imidazol-...)
Affinity DataIC50:  190nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033977(1-{2-[2-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-et...)
Affinity DataIC50:  190nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033956(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-di-furan-2-yl-1H...)
Affinity DataIC50:  200nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033979(1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50:  230nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033991(3-(2,4-Difluoro-phenyl)-1-(2-{[2-(4,5-diphenyl-1H-...)
Affinity DataIC50:  240nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033994(1-(2-{[2-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-e...)
Affinity DataIC50:  260nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033983(1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50:  270nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033976(1-{5-[4,5-Bis-(4-methylsulfanyl-phenyl)-1H-imidazo...)
Affinity DataIC50:  280nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033962(1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50:  340nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033961(1-{5-[4,5-Bis-(2-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50:  350nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033970(1-(2-{[2-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-e...)
Affinity DataIC50:  350nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033965(1-(2-{3-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-...)
Affinity DataIC50:  480nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033972(1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50:  500nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033985(CHEMBL11071 | {5-[4,5-Bis-(4-methoxy-phenyl)-1H-im...)
Affinity DataIC50:  640nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033987(1-(2-Diethylamino-ethyl)-1-[5-(4,5-diphenyl-1H-imi...)
Affinity DataIC50:  660nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033986(1-(2-{2-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-...)
Affinity DataIC50:  850nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033992(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-di-pyridin-2-yl-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033958(1-(2-{2-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033988(1-(2-{2-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-...)
Affinity DataIC50:  2.30E+3nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033996(1-{5-[4,5-Bis-(4-hydroxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50:  2.40E+3nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033973(1-{5-[4,5-Bis-(4-trifluoromethyl-phenyl)-1H-imidaz...)
Affinity DataIC50:  3.99E+4nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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