Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50036396
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034001(3-(1-Benzyl-piperidin-4-yl)-1-(1-ethyl-2-methyl-1H...)
Affinity DataIC50:  4.30nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  6nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034002(3-(1-Benzyl-piperidin-4-yl)-1-(2-methyl-benzothiaz...)
Affinity DataIC50:  6.80nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  8nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034003(3-(1-Benzyl-piperidin-4-yl)-1-(2-methyl-1H-benzoim...)
Affinity DataIC50:  12nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  19nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034000(3-(1-Benzyl-piperidin-4-yl)-1-(2,3-dihydro-benzo[1...)
Affinity DataIC50:  30nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034004(3-(1-Benzyl-piperidin-4-yl)-1-(2-phenyl-1H-benzoim...)
Affinity DataIC50:  33nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  73nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  267nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50033999(3-(1-Benzyl-piperidin-4-yl)-1-phenyl-propan-1-one;...)
Affinity DataIC50:  305nMAssay Description:Concentration required to inhibit 50% of Acetylcholinesterase obtained from human erythrocytes was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034004(3-(1-Benzyl-piperidin-4-yl)-1-(2-phenyl-1H-benzoim...)
Affinity DataIC50:  890nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  2.90E+3nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034002(3-(1-Benzyl-piperidin-4-yl)-1-(2-methyl-benzothiaz...)
Affinity DataIC50:  3.40E+3nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034001(3-(1-Benzyl-piperidin-4-yl)-1-(1-ethyl-2-methyl-1H...)
Affinity DataIC50:  4.20E+3nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50033999(3-(1-Benzyl-piperidin-4-yl)-1-phenyl-propan-1-one;...)
Affinity DataIC50:  4.30E+3nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034000(3-(1-Benzyl-piperidin-4-yl)-1-(2,3-dihydro-benzo[1...)
Affinity DataIC50:  4.80E+3nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034003(3-(1-Benzyl-piperidin-4-yl)-1-(2-methyl-1H-benzoim...)
Affinity DataIC50:  6.20E+3nMAssay Description:Concentration required to inhibit 50% of Butyrylcholinesterase obtained from human serum was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed