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Found 39 Enz. Inhib. hit(s) with all data for entry = 50036219
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50001028((+)-PENTAZOCINE | (-)-pentazocine | (2R,6R,11R)-6,...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040191(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-pyrrolidin...)
Affinity DataKi:  125nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040193(1-(1-Benzo[b]thiophen-2-yl-cyclohexyl)-pyrrolidine...)
Affinity DataKi:  168nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040192(1-(1-Benzo[b]thiophen-2-yl-cyclohexyl)-azepane | C...)
Affinity DataKi:  674nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040197(1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-pyrrolidin...)
Affinity DataKi:  720nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040199(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-piperidine...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040195(1-Benzo[b]thiophen-2-yl-cyclopentylamine | CHEMBL1...)
Affinity DataKi:  1.73E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM83449(1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...)
Affinity DataKi:  1.77E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040189(1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-piperidine...)
Affinity DataKi:  2.23E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040196(1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-azepane | ...)
Affinity DataKi:  2.71E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040198(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-azepane | ...)
Affinity DataKi:  2.89E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040190(1-Benzo[b]thiophen-2-yl-cyclohexylamine | CHEMBL18...)
Affinity DataKi:  3.17E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040194(1-Benzo[b]thiophen-2-yl-cycloheptylamine | CHEMBL1...)
Affinity DataKi:  9.17E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50005534(1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)piperidine ...)
Affinity DataIC50:  0.660nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040193(1-(1-Benzo[b]thiophen-2-yl-cyclohexyl)-pyrrolidine...)
Affinity DataIC50:  6.70nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040193(1-(1-Benzo[b]thiophen-2-yl-cyclohexyl)-pyrrolidine...)
Affinity DataIC50:  12nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040191(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-pyrrolidin...)
Affinity DataIC50:  13nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040199(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-piperidine...)
Affinity DataIC50:  15nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040189(1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-piperidine...)
Affinity DataIC50:  19nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040191(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-pyrrolidin...)
Affinity DataIC50:  26nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040192(1-(1-Benzo[b]thiophen-2-yl-cyclohexyl)-azepane | C...)
Affinity DataIC50:  36nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040192(1-(1-Benzo[b]thiophen-2-yl-cyclohexyl)-azepane | C...)
Affinity DataIC50:  36nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50005534(1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)piperidine ...)
Affinity DataIC50:  41nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040197(1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-pyrrolidin...)
Affinity DataIC50:  52nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040197(1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-pyrrolidin...)
Affinity DataIC50:  52nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040198(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-azepane | ...)
Affinity DataIC50:  62nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040198(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-azepane | ...)
Affinity DataIC50:  62nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040196(1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-azepane | ...)
Affinity DataIC50:  67nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040199(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-piperidine...)
Affinity DataIC50:  76nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  107nMAssay Description:Binding affinity of compound at site labeled by [3H]-cocaine in rat forebrain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040189(1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-piperidine...)
Affinity DataIC50:  111nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040190(1-Benzo[b]thiophen-2-yl-cyclohexylamine | CHEMBL18...)
Affinity DataIC50:  123nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  187nMAssay Description:Binding affinity for compound at site labeled by [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) in rat forebrain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040196(1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-azepane | ...)
Affinity DataIC50:  386nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040194(1-Benzo[b]thiophen-2-yl-cycloheptylamine | CHEMBL1...)
Affinity DataIC50:  416nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040195(1-Benzo[b]thiophen-2-yl-cyclopentylamine | CHEMBL1...)
Affinity DataIC50:  630nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040190(1-Benzo[b]thiophen-2-yl-cyclohexylamine | CHEMBL18...)
Affinity DataIC50:  684nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040195(1-Benzo[b]thiophen-2-yl-cyclopentylamine | CHEMBL1...)
Affinity DataIC50:  933nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040194(1-Benzo[b]thiophen-2-yl-cycloheptylamine | CHEMBL1...)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed