Affinity DataIC50: 1nMAssay Description:Inhibitory concentration of the compound for DHFR in Pneumocystis cariniiMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration of the compound for DHFR in rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration of the compound for DHFR in recombinant humanMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration of the compound for DHFR in Lactobacillus caseiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration of the compound for DHFR in Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibitory concentration of the compound for DHFR in Pneumocystis cariniiMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration of the compound for DHFR in recombinant humanMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration of the compound for DHFR in Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibitory concentration of the compound for DHFR in rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibitory concentration of the compound for DHFR in recombinant humanMore data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibitory concentration of the compound for DHFR in Lactobacillus caseiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibitory concentration of the compound for DHFR in Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibitory concentration of the compound for DHFR in Pneumocystis cariniiMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory concentration of the compound for DHFR in rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibitory concentration of the compound for DHFR in Lactobacillus caseiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: >3.90E+3nMAssay Description:Inhibitory concentration of the compound for DHFR in Toxoplasma gondiiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory concentration of the compound for DHFR in Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibitory concentration of the compound for DHFR in Pneumocystis cariniiMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibitory concentration of the compound for DHFR in Pneumocystis cariniiMore data for this Ligand-Target Pair
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in recombinant humanMore data for this Ligand-Target Pair
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in recombinant humanMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 1.98E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in Toxoplasma gondiiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: >2.10E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: >2.10E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in Pneumocystis cariniiMore data for this Ligand-Target Pair
Affinity DataIC50: >2.10E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in recombinant humanMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: 2.56E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: >2.60E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in recombinant humanMore data for this Ligand-Target Pair
Affinity DataIC50: >2.60E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in Lactobacillus caseiMore data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration of the compound against L. casei AICAR formyltransferaseMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration of the compound in glycinamide ribonucleotide formyltransferase (GARFT) L. caseiMore data for this Ligand-Target Pair
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration of the compound in glycinamide ribonucleotide formyltransferase (GARFT) L. caseiMore data for this Ligand-Target Pair
TargetBifunctional purine biosynthesis protein ATIC(Homo sapiens (Human))
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration of the compound against L. casei AICAR formyltransferaseMore data for this Ligand-Target Pair
Affinity DataIC50: >3.10E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: >3.50E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in Pneumocystis cariniiMore data for this Ligand-Target Pair
Affinity DataIC50: 3.52E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: >3.70E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in rat liverMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 8.93E+4nMAssay Description:Inhibitory concentration of the compound for DHFR in Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibitory concentration of the compound for TS in humanMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory concentration of the compound for TS in humanMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory concentration of the compound for TS in Lactobacillus caseiMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory concentration of the compound for TS in humanMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory concentration of the compound for TS in Lactobacillus caseiMore data for this Ligand-Target Pair