Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with all data for entry = 50048917
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50231562(CHEMBL109965)
Affinity DataIC50:  170nMAssay Description:Inhibition of partially-purified PDE 4 from human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50231563(CHEMBL326068)
Affinity DataIC50:  740nMAssay Description:Inhibition of partially-purified PDE 4 from human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042058((-)-rolipram | (4R)-4-[3-(cyclopentyloxy)-4-methox...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of partially-purified PDE 4 from human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50042056((R)-4-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrrolid...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of partially-purified PDE 4 from human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed