Compile Data Set for Download or QSAR
maximum 50k data
Found 111 Enz. Inhib. hit(s) with all data for entry = 50006233
TargetSerine protease 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046358(CHEMBL110780 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046355(CHEMBL110898 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046373(CHEMBL108670 | {1-(3,4-Dichloro-phenyl)-2-[2-(1-fo...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046358(CHEMBL110780 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50060000((S)-1-((R)-2-Methylamino-2-phenyl-acetyl)-pyrrolid...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50060000((S)-1-((R)-2-Methylamino-2-phenyl-acetyl)-pyrrolid...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046356(1-(2-Amino-2-phenyl-acetyl)-pyrrolidine-2-carboxyl...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046352(1-(1,2,3,4-Tetrahydro-isoquinoline-3-carbonyl)-pyr...)
Affinity DataIC50:  19nMAssay Description:Inhibitory activity against factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046356(1-(2-Amino-2-phenyl-acetyl)-pyrrolidine-2-carboxyl...)
Affinity DataIC50:  19nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046368(CHEMBL320988 | [2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  19nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046356(1-(2-Amino-2-phenyl-acetyl)-pyrrolidine-2-carboxyl...)
Affinity DataIC50:  19nMAssay Description:Inhibitory activity against factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046352(1-(1,2,3,4-Tetrahydro-isoquinoline-3-carbonyl)-pyr...)
Affinity DataIC50:  19nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046352(1-(1,2,3,4-Tetrahydro-isoquinoline-3-carbonyl)-pyr...)
Affinity DataIC50:  19nMAssay Description:Compound was tested in vitro for inhibitory activity against t-PA (tissue plasminogen activator)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046356(1-(2-Amino-2-phenyl-acetyl)-pyrrolidine-2-carboxyl...)
Affinity DataIC50:  19nMAssay Description:Compound was tested in vitro for inhibitory activity against t-PA (tissue plasminogen activator)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046352(1-(1,2,3,4-Tetrahydro-isoquinoline-3-carbonyl)-pyr...)
Affinity DataIC50:  19nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046355(CHEMBL110898 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  23nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046368(CHEMBL320988 | [2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  27nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046373(CHEMBL108670 | {1-(3,4-Dichloro-phenyl)-2-[2-(1-fo...)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046359(CHEMBL109109 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  29nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046360(CHEMBL104472 | {1-Benzyl-2-[2-(1-formyl-4-guanidin...)
Affinity DataIC50:  45nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046360(CHEMBL104472 | {1-Benzyl-2-[2-(1-formyl-4-guanidin...)
Affinity DataIC50:  45nMAssay Description:Compound was tested in vitro for inhibitory activity against t-PA (tissue plasminogen activator)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046360(CHEMBL104472 | {1-Benzyl-2-[2-(1-formyl-4-guanidin...)
Affinity DataIC50:  45nMAssay Description:Inhibitory activity against factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046360(CHEMBL104472 | {1-Benzyl-2-[2-(1-formyl-4-guanidin...)
Affinity DataIC50:  45nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046358(CHEMBL110780 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  50nMAssay Description:Inhibitory activity against factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046358(CHEMBL110780 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  55nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046359(CHEMBL109109 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  55nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046373(CHEMBL108670 | {1-(3,4-Dichloro-phenyl)-2-[2-(1-fo...)
Affinity DataIC50:  69nMAssay Description:Inhibitory activity against factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046362(CHEMBL319930 | {1-Cyclohexyl-2-[2-(1-formyl-4-guan...)
Affinity DataIC50:  81nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046362(CHEMBL319930 | {1-Cyclohexyl-2-[2-(1-formyl-4-guan...)
Affinity DataIC50:  81nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046362(CHEMBL319930 | {1-Cyclohexyl-2-[2-(1-formyl-4-guan...)
Affinity DataIC50:  81nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046362(CHEMBL319930 | {1-Cyclohexyl-2-[2-(1-formyl-4-guan...)
Affinity DataIC50:  81nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046362(CHEMBL319930 | {1-Cyclohexyl-2-[2-(1-formyl-4-guan...)
Affinity DataIC50:  81nMAssay Description:Inhibitory activity against factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046365(1-(2-Phenyl-butyryl)-pyrrolidine-2-carboxylic acid...)
Affinity DataIC50:  94nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046372(CHEMBL318998 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  98nMAssay Description:Inhibitory activity against factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046372(CHEMBL318998 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  98nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046372(CHEMBL318998 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  98nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046372(CHEMBL318998 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  98nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046372(CHEMBL318998 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  98nMAssay Description:Compound was tested in vitro for inhibitory activity against t-PA (tissue plasminogen activator)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046368(CHEMBL320988 | [2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046363(1-(2-Phenyl-pentanoyl)-pyrrolidine-2-carboxylic ac...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046361(CHEMBL2370418 | {2-[2-(1-Formyl-4-guanidino-butylc...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046359(CHEMBL109109 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046373(CHEMBL108670 | {1-(3,4-Dichloro-phenyl)-2-[2-(1-fo...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046365(1-(2-Phenyl-butyryl)-pyrrolidine-2-carboxylic acid...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046361(CHEMBL2370418 | {2-[2-(1-Formyl-4-guanidino-butylc...)
Affinity DataIC50:  190nMAssay Description:Inhibitory activity against factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046361(CHEMBL2370418 | {2-[2-(1-Formyl-4-guanidino-butylc...)
Affinity DataIC50:  190nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046360(CHEMBL104472 | {1-Benzyl-2-[2-(1-formyl-4-guanidin...)
Affinity DataIC50:  190nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046361(CHEMBL2370418 | {2-[2-(1-Formyl-4-guanidino-butylc...)
Affinity DataIC50:  190nMAssay Description:Compound was tested in vitro for inhibitory activity against t-PA (tissue plasminogen activator)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046361(CHEMBL2370418 | {2-[2-(1-Formyl-4-guanidino-butylc...)
Affinity DataIC50:  190nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50046359(CHEMBL109109 | {2-[2-(1-Formyl-4-guanidino-butylca...)
Affinity DataIC50:  210nMAssay Description:Inhibitory activity against factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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