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Found 100 Enz. Inhib. hit(s) with all data for entry = 50006476
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049619(3-Chloro-4,4',5'-trifluoro-[1,1';2',1'']terphenyl-...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049644(4,4',5'-Trifluoro-3-methyl-[1,1';2',1'']terphenyl-...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049653(4-Chloro-4',5'-difluoro-3-methyl-[1,1';2',1'']terp...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049625(3-Chloro-4',5'-difluoro-4-methyl-[1,1';2',1'']terp...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049622(2'-Benzo[1,3]dioxol-5-yl-4',5'-difluoro-biphenyl-4...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049645(4',5'-Difluoro-4''-methyl-[1,1';2',1'']terphenyl-4...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049659(4',5',4''-Trifluoro-[1,1';2',1'']terphenyl-4-sulfo...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049623(4,4',5'-Trifluoro-4''-methanesulfonyl-3-methyl-[1,...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049662(4',5'-Difluoro-3,4-dimethyl-[1,1';2',1'']terphenyl...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049656(4',5'-Difluoro-4-methoxy-3-methyl-[1,1';2',1'']ter...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049651(4-Chloro-[1,1'';2'',1'''']terphenyl-4''''-sulfonic...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049646(3-Chloro-4-dimethylamino-4',5'-difluoro-[1,1';2',1...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049617(4-Chloro-4',5'-difluoro-4''-methanesulfonyl-3-meth...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049660(4',5'-Difluoro-4''-methanesulfonyl-4-methyl-[1,1';...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049649((3-Chloro-4',5'-difluoro-4''-methanesulfonyl-[1,1'...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049642(3-Chloro-4,4',5'-trifluoro-4''-methanesulfonyl-[1,...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049635(5-(4,5-Difluoro-4'-methanesulfonyl-biphenyl-2-yl)-...)
Affinity DataIC50:  12nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049636(4',5'-Difluoro-4''-methanesulfonyl-4-methoxy-3-met...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049652(3-Chloro-4',5'-difluoro-4-methoxy-[1,1';2',1'']ter...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049639(3,4',5'-Trifluoro-4-methoxy-[1,1';2',1'']terphenyl...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049637(3-Chloro-4',5'-difluoro-4''-methanesulfonyl-4-meth...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049632(4',5',4''-Trifluoro-4-methanesulfonyl-[1,1';2',1''...)
Affinity DataIC50:  14nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049633(3-Chloro-4-fluoro-[1,1'';2'',1'''']terphenyl-4''''...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049641(3-Chloro-4',5'-difluoro-4''-methanesulfonyl-4-meth...)
Affinity DataIC50:  19nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049618(3-Chloro-4-methoxy-[1,1'';2'',1'''']terphenyl-4'''...)
Affinity DataIC50:  19nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049634(3,4',5'-Trifluoro-4''-methanesulfonyl-4-methoxy-[1...)
Affinity DataIC50:  21nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049621(3,5-Dichloro-4',5'-difluoro-4-methoxy-[1,1';2',1''...)
Affinity DataIC50:  21nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049640(4',5'-Difluoro-4''-methanesulfonyl-3,4-dimethyl-[1...)
Affinity DataIC50:  23nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049647(2'-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-4',5'-diflu...)
Affinity DataIC50:  32nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049661(3''''-Fluoro-4''''-methoxy-[1,1'';2'',1'''']terphe...)
Affinity DataIC50:  33nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049663(4',5'-Difluoro-2'-(6-methyl-pyridin-3-yl)-biphenyl...)
Affinity DataIC50:  51nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049657(4''-Fluoro-[1,1';2',1'']terphenyl-4-sulfonic acid ...)
Affinity DataIC50:  61nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049616(4',5'-Difluoro-3,4-dimethoxy-[1,1';2',1'']terpheny...)
Affinity DataIC50:  65nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049650(5-(4-Fluoro-phenyl)-6-(4-methanesulfonyl-phenyl)-b...)
Affinity DataIC50:  83nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049629(4''''-Chloro-4-methanesulfonyl-[1,1'';2'',1'''']te...)
Affinity DataIC50:  140nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049628(5-(4,5-Difluoro-4'-methanesulfonyl-biphenyl-2-yl)-...)
Affinity DataIC50:  170nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049654(4',5'-Dichloro-4''-fluoro-4-methanesulfonyl-[1,1';...)
Affinity DataIC50:  240nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049631(4''''-Fluoro-4-methanesulfonyl-[1,1'';2'',1'''']te...)
Affinity DataIC50:  260nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049620(4',5'-Difluoro-2'-(5-methyl-pyridin-2-yl)-biphenyl...)
Affinity DataIC50:  330nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049643(4',5'-Difluoro-4''-methanesulfonyl-3,4-dimethoxy-[...)
Affinity DataIC50:  340nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049624(6-(4,5-Difluoro-4'-methanesulfonyl-biphenyl-2-yl)-...)
Affinity DataIC50:  340nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049630(3''''-Chloro-4''''-fluoro-4-methanesulfonyl-[1,1''...)
Affinity DataIC50:  360nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049646(3-Chloro-4-dimethylamino-4',5'-difluoro-[1,1';2',1...)
Affinity DataIC50:  590nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  900nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049622(2'-Benzo[1,3]dioxol-5-yl-4',5'-difluoro-biphenyl-4...)
Affinity DataIC50:  1.70E+3nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049644(4,4',5'-Trifluoro-3-methyl-[1,1';2',1'']terphenyl-...)
Affinity DataIC50:  3.70E+3nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049653(4-Chloro-4',5'-difluoro-3-methyl-[1,1';2',1'']terp...)
Affinity DataIC50:  3.90E+3nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049651(4-Chloro-[1,1'';2'',1'''']terphenyl-4''''-sulfonic...)
Affinity DataIC50:  3.90E+3nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50049619(3-Chloro-4,4',5'-trifluoro-[1,1';2',1'']terphenyl-...)
Affinity DataIC50:  5.50E+3nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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