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PubMed code 8759624

Compile data set for download or QSAR
Found 1 hit of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tumor necrosis factor


(Homo sapiens (Human))
BDBM50052428
PNG
(2-(2,6-Dioxo-piperidin-3-yl)-4,5,6,7-tetrafluoro-i...)
Show SMILES Fc1c2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c(F)c(F)c1F
Show InChI InChI=1S/C13H6F4N2O4/c14-7-5-6(8(15)10(17)9(7)16)13(23)19(12(5)22)3-1-2-4(20)18-11(3)21/h3H,1-2H2,(H,18,20,21)
PDB
MMDB

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Article
PubMed
n/an/a 400n/an/an/an/an/an/a



Institute of Technology

Curated by ChEMBL


Assay Description
Inhibitory activity against TNF-alpha production


J Med Chem 39: 3044-5 (1996)


Article DOI: 10.1021/jm960284r
BindingDB Entry DOI: 10.7270/Q2RB73PR
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%