Affinity Data by BDB articleid=9094

Articleid 9094

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Replicase polyprotein 1ab (2019-nCoV)	BDBM442799 (RS102859) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	n/a	n/a	n/a	n/a	1.98E+4	n/a	n/a	n/a	n/a
Center for Free-Electron Laser Science				Assay Description Briefly, Vero E6 cells (ATCC CRL-1586) seeded at 3.5 � 104 cells/well in 96-well plates were inoculated with 50 μ l of serial tenfold ...				bioRxiv 2020: (2020)
Center for Free-Electron Laser Science				More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM24654 (4-N-(2,6-dichlorobenzene)-3-N-(piperidin-4-yl)-1H-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase MMDB PC cid PC sid PDB UniChem Patents Similars	n/a	n/a	n/a	n/a	2.52E+4	n/a	n/a	n/a	n/a
Center for Free-Electron Laser Science				Assay Description Briefly, Vero E6 cells (ATCC CRL-1586) seeded at 3.5 � 104 cells/well in 96-well plates were inoculated with 50 μ l of serial tenfold ...				bioRxiv 2020: (2020)
Center for Free-Electron Laser Science				More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50083351 ((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...) Show SMILES CC(C(O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	n/a	n/a	n/a	n/a	3.93E+4	n/a	n/a	n/a	n/a
Center for Free-Electron Laser Science				Assay Description Briefly, Vero E6 cells (ATCC CRL-1586) seeded at 3.5 � 104 cells/well in 96-well plates were inoculated with 50 μ l of serial tenfold ...				bioRxiv 2020: (2020)
Center for Free-Electron Laser Science				More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50399407 (CHEMBL2178284 \| MUT056399) Show SMILES CCc1cc(O)c(Oc2ccc(cc2F)C(N)=O)cc1F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	n/a	n/a	n/a	n/a	3.82E+4	n/a	n/a	n/a	n/a
Center for Free-Electron Laser Science				Assay Description Briefly, Vero E6 cells (ATCC CRL-1586) seeded at 3.5 � 104 cells/well in 96-well plates were inoculated with 50 μ l of serial tenfold ...				bioRxiv 2020: (2020)
Center for Free-Electron Laser Science				More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM31090 ((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEBI PC cid PC sid PDB UniChem Patents Similars	n/a	n/a	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a
Center for Free-Electron Laser Science				Assay Description Briefly, Vero E6 cells (ATCC CRL-1586) seeded at 3.5 � 104 cells/well in 96-well plates were inoculated with 50 μ l of serial tenfold ...				bioRxiv 2020: (2020)
Center for Free-Electron Laser Science				More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM442751 (Triglycidyl isocyanurate) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
Center for Free-Electron Laser Science				Assay Description Briefly, Vero E6 cells (ATCC CRL-1586) seeded at 3.5 � 104 cells/well in 96-well plates were inoculated with 50 μ l of serial tenfold ...				bioRxiv 2020: (2020)
Center for Free-Electron Laser Science				More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM442750 (Isofloxythepin) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	n/a	n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a
Center for Free-Electron Laser Science				Assay Description Briefly, Vero E6 cells (ATCC CRL-1586) seeded at 3.5 � 104 cells/well in 96-well plates were inoculated with 50 μ l of serial tenfold ...				bioRxiv 2020: (2020)
Center for Free-Electron Laser Science				More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM50084655 (CHEMBL92708 \| Z-Leu-Nle-CHO \| [(S)-1-((S)-1-Formyl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	n/a	n/a	n/a	n/a	<1.56E+3	n/a	n/a	n/a	n/a
Center for Free-Electron Laser Science				Assay Description Briefly, Vero E6 cells (ATCC CRL-1586) seeded at 3.5 � 104 cells/well in 96-well plates were inoculated with 50 μ l of serial tenfold ...				bioRxiv 2020: (2020)
Center for Free-Electron Laser Science				More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM442744 (Tolperisone) Show SMILES CC(CN1CCCCC1)C(=O)c1ccc(C)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar	PC cid PC sid UniChem	n/a	n/a	n/a	n/a	1.92E+4	n/a	n/a	n/a	n/a
Center for Free-Electron Laser Science				Assay Description Briefly, Vero E6 cells (ATCC CRL-1586) seeded at 3.5 � 104 cells/well in 96-well plates were inoculated with 50 μ l of serial tenfold ...				bioRxiv 2020: (2020)
Center for Free-Electron Laser Science				More data for this Ligand-Target Pair

* indicates data uncertainty>20%