Compile Data Set for Download or QSAR
maximum 50k data
Found 32 Enz. Inhib. hit(s) with all data for entry = 50007222
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059890(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Affinity DataKi:  62nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataKi:  118nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059893(2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine | CHE...)
Affinity DataKi:  177nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059890(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Affinity DataKi:  205nMAssay Description:Antagonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]- rauwolscine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059893(2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine | CHE...)
Affinity DataKi:  216nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059890(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Affinity DataKi:  302nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]-5-HT radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Affinity DataKi:  303nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataKi:  311nMAssay Description:Antagonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]-rauwolscine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059890(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Affinity DataKi:  335nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataKi:  368nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataKi:  368nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataKi:  523nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]-5-HT radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Affinity DataKi:  551nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059893(2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine | CHE...)
Affinity DataKi:  555nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]-5-HT radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059890(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Affinity DataKi:  654nMAssay Description:Antagonist activity at cloned human 5-hydroxytryptamine 2C receptor using [3H]-mesulergine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Affinity DataKi:  795nMAssay Description:Agonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]-5-HT radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataKi:  1.11E+3nMAssay Description:Antagonist activity at cloned human 5-hydroxytryptamine 2C receptor using [3H]-mesulergine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059893(2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine | CHE...)
Affinity DataKi:  2.10E+3nMAssay Description:Ability to displace [3H]-ketanserin from rat cortical homogenate 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataKi:  2.50E+3nMAssay Description:Ability to displace [3H]-ketanserin from rat cortical homogenate 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059890(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Affinity DataKi:  4.44E+3nMAssay Description:Antagonist activity at cloned human 5-hydroxytryptamine 2A receptor using [3H]-Ketanserin radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Affinity DataKi:  5.50E+3nMAssay Description:Ability to displace [3H]-ketanserin from rat cortical homogenate 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataKi:  6.20E+3nMAssay Description:Ability to displace [3H]-8-OH-DPAT from rat hippocampal homogenate 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Affinity DataKi:  6.90E+3nMAssay Description:Ability to displace [3H]-8-OH-DPAT from rat hippocampal homogenate 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059893(2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine | CHE...)
Affinity DataKi:  6.90E+3nMAssay Description:Ability to displace [3H]-8-OH-DPAT from rat hippocampal homogenate 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059893(2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine | CHE...)
Affinity DataEC50:  4.00E+3nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Affinity DataEC50:  2.40E+4nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059893(2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine | CHE...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataEC50:  3.00E+3nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast expressing 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059890(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059891(1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...)
Affinity DataEC50:  4.00E+3nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50059890(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Affinity DataEC50:  1.00E+3nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed