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PubMed code 9484506

Compile data set for download or QSAR
Found 49 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062860
PNG
(CHEMBL132620 | N-({[3-(3-Bromo-2-methyl-imidazo[1,...)
Show SMILES CN(C)CC(=O)NCC(=O)N(C)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C22H24BrCl2N5O3/c1-13-21(23)30-9-5-6-17(22(30)27-13)33-12-14-15(24)7-8-16(20(14)25)29(4)19(32)10-26-18(31)11-28(2)3/h5-9H,10-12H2,1-4H3,(H,26,31)
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n/an/a 2.40n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062871
PNG
(CHEMBL554431 | Pentanoic acid ({[3-(3-bromo-2-meth...)
Show SMILES CCCCC(=O)NCC(=O)N(C)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C23H25BrCl2N4O3/c1-4-5-8-19(31)27-12-20(32)29(3)17-10-9-16(25)15(21(17)26)13-33-18-7-6-11-30-22(24)14(2)28-23(18)30/h6-7,9-11H,4-5,8,12-13H2,1-3H3,(H,27,31)
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n/an/a 7.80n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062878
PNG
(CHEMBL131517 | N-({[3-(3-Bromo-2-methyl-imidazo[1,...)
Show SMILES CCCC(=O)NCC(=O)N(C)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C22H23BrCl2N4O3/c1-4-6-18(30)26-11-19(31)28(3)16-9-8-15(24)14(20(16)25)12-32-17-7-5-10-29-21(23)13(2)27-22(17)29/h5,7-10H,4,6,11-12H2,1-3H3,(H,26,30)
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n/an/a 8.90n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062864
PNG
(CHEMBL336116 | N-[3-(3-Bromo-2-methyl-imidazo[1,2-...)
Show SMILES CCNC(=O)NCC(=O)N(C)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C21H22BrCl2N5O3/c1-4-25-21(31)26-10-17(30)28(3)15-8-7-14(23)13(18(15)24)11-32-16-6-5-9-29-19(22)12(2)27-20(16)29/h5-9H,4,10-11H2,1-3H3,(H2,25,26,31)
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n/an/a 9n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062863
PNG
(2-Acetylamino-N-[3-(3-bromo-2-methyl-imidazo[1,2-a...)
Show SMILES CN(C(=O)CNC(C)=O)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C20H19BrCl2N4O3/c1-11-19(21)27-8-4-5-16(20(27)25-11)30-10-13-14(22)6-7-15(18(13)23)26(3)17(29)9-24-12(2)28/h4-8H,9-10H2,1-3H3,(H,24,28)
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n/an/a 16n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062863
PNG
(2-Acetylamino-N-[3-(3-bromo-2-methyl-imidazo[1,2-a...)
Show SMILES CN(C(=O)CNC(C)=O)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C20H19BrCl2N4O3/c1-11-19(21)27-8-4-5-16(20(27)25-11)30-10-13-14(22)6-7-15(18(13)23)26(3)17(29)9-24-12(2)28/h4-8H,9-10H2,1-3H3,(H,24,28)
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n/an/a 16n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062865
PNG
(CHEMBL543700 | N-({[3-(3-Bromo-2-methyl-imidazo[1,...)
Show SMILES CCC(=O)NCC(=O)N(C)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C21H21BrCl2N4O3/c1-4-17(29)25-10-18(30)27(3)15-8-7-14(23)13(19(15)24)11-31-16-6-5-9-28-20(22)12(2)26-21(16)28/h5-9H,4,10-11H2,1-3H3,(H,25,29)
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n/an/a 19n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062898
PNG
(CHEMBL554412 | N-[3-(3-Bromo-2-methyl-imidazo[1,2-...)
Show SMILES CCCNC(=O)NCC(=O)N(C)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C22H24BrCl2N5O3/c1-4-9-26-22(32)27-11-18(31)29(3)16-8-7-15(24)14(19(16)25)12-33-17-6-5-10-30-20(23)13(2)28-21(17)30/h5-8,10H,4,9,11-12H2,1-3H3,(H2,26,27,32)
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n/an/a 26n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062905
PNG
(3-Bromo-8-(2,6-dichloro-3-nitro-benzyloxy)-2-methy...)
Show SMILES Cc1nc2c(OCc3c(Cl)ccc(c3Cl)[N+]([O-])=O)cccn2c1Br
Show InChI InChI=1S/C15H10BrCl2N3O3/c1-8-14(16)20-6-2-3-12(15(20)19-8)24-7-9-10(17)4-5-11(13(9)18)21(22)23/h2-6H,7H2,1H3
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n/an/a 42n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062899
PNG
(CHEMBL556176 | N-[3-(3-Bromo-2-methyl-imidazo[1,2-...)
Show SMILES CNC(=O)NCC(=O)N(C)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C20H20BrCl2N5O3/c1-11-18(21)28-8-4-5-15(19(28)26-11)31-10-12-13(22)6-7-14(17(12)23)27(3)16(29)9-25-20(30)24-2/h4-8H,9-10H2,1-3H3,(H2,24,25,30)
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n/an/a 46n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062891
PNG
(CHEMBL358234 | N-[3-(3-Bromo-2-methyl-imidazo[1,2-...)
Show SMILES CN(C(C)=O)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C18H16BrCl2N3O2/c1-10-17(19)24-8-4-5-15(18(24)22-10)26-9-12-13(20)6-7-14(16(12)21)23(3)11(2)25/h4-8H,9H2,1-3H3
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n/an/a 54n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062868
PNG
(CHEMBL155339 | N-[3-(3-Bromo-2-methyl-imidazo[1,2-...)
Show SMILES CCC(=O)N(C)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C19H18BrCl2N3O2/c1-4-16(26)24(3)14-8-7-13(21)12(17(14)22)10-27-15-6-5-9-25-18(20)11(2)23-19(15)25/h5-9H,4,10H2,1-3H3
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n/an/a 72n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062901
PNG
(CHEMBL154625 | N-[3-(3-Bromo-2-methyl-imidazo[1,2-...)
Show SMILES CCN(C(C)=O)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C19H18BrCl2N3O2/c1-4-24(12(3)26)15-8-7-14(21)13(17(15)22)10-27-16-6-5-9-25-18(20)11(2)23-19(16)25/h5-9H,4,10H2,1-3H3
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n/an/a 150n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062893
PNG
(3-Chloro-8-(2,6-dichloro-benzyloxy)-2-methyl-imida...)
Show SMILES Cc1nc2c(OCc3c(Cl)cccc3Cl)cccn2c1Cl
Show InChI InChI=1S/C15H11Cl3N2O/c1-9-14(18)20-7-3-6-13(15(20)19-9)21-8-10-11(16)4-2-5-12(10)17/h2-7H,8H2,1H3
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n/an/a 200n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062884
PNG
(3-Bromo-8-(2,6-dichloro-benzyloxy)-2-methyl-imidaz...)
Show SMILES Cc1nc2c(OCc3c(Cl)cccc3Cl)cccn2c1Br
Show InChI InChI=1S/C15H11BrCl2N2O/c1-9-14(16)20-7-3-6-13(15(20)19-9)21-8-10-11(17)4-2-5-12(10)18/h2-7H,8H2,1H3
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n/an/a 230n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062890
PNG
(1-[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-ylo...)
Show SMILES CNC(=O)N(C)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C18H17BrCl2N4O2/c1-10-16(19)25-8-4-5-14(17(25)23-10)27-9-11-12(20)6-7-13(15(11)21)24(3)18(26)22-2/h4-8H,9H2,1-3H3,(H,22,26)
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n/an/a 350n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062867
PNG
(2-Amino-N-[3-(3-bromo-2-methyl-imidazo[1,2-a]pyrid...)
Show SMILES CN(C(=O)CN)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C18H17BrCl2N4O2/c1-10-17(19)25-7-3-4-14(18(25)23-10)27-9-11-12(20)5-6-13(16(11)21)24(2)15(26)8-22/h3-7H,8-9,22H2,1-2H3
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n/an/a 380n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062886
PNG
(CHEMBL154633 | [3-(3-Bromo-2-methyl-imidazo[1,2-a]...)
Show SMILES CCN(C)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C18H18BrCl2N3O/c1-4-23(3)14-8-7-13(20)12(16(14)21)10-25-15-6-5-9-24-17(19)11(2)22-18(15)24/h5-9H,4,10H2,1-3H3
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n/an/a 410n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062888
PNG
(CHEMBL156847 | N-[3-(3-Bromo-2-methyl-imidazo[1,2-...)
Show SMILES CN(C(C)=O)c1c(Cl)cc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C18H15BrCl3N3O2/c1-9-17(19)25-6-4-5-14(18(25)23-9)27-8-11-12(20)7-13(21)16(15(11)22)24(3)10(2)26/h4-7H,8H2,1-3H3
MMDB

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n/an/a 420n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062906
PNG
(3-Bromo-2-methyl-8-(2,3,6-trichloro-benzyloxy)-imi...)
Show SMILES Cc1nc2c(OCc3c(Cl)ccc(Cl)c3Cl)cccn2c1Br
Show InChI InChI=1S/C15H10BrCl3N2O/c1-8-14(16)21-6-2-3-12(15(21)20-8)22-7-9-10(17)4-5-11(18)13(9)19/h2-6H,7H2,1H3
MMDB

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n/an/a 490n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062908
PNG
(Acetic acid {[3-(3-bromo-2-methyl-imidazo[1,2-a]py...)
Show SMILES CN(C(=O)COC(C)=O)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C20H18BrCl2N3O4/c1-11-19(21)26-8-4-5-16(20(26)24-11)30-9-13-14(22)6-7-15(18(13)23)25(3)17(28)10-29-12(2)27/h4-8H,9-10H2,1-3H3
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n/an/a 500n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062879
PNG
(3-Bromo-8-(2,6-dichloro-3-methoxy-benzyloxy)-2-met...)
Show SMILES COc1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C16H13BrCl2N2O2/c1-9-15(17)21-7-3-4-13(16(21)20-9)23-8-10-11(18)5-6-12(22-2)14(10)19/h3-7H,8H2,1-2H3
MMDB

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n/an/a 540n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062907
PNG
(CHEMBL154122 | N-[3-(3-Bromo-2-methyl-imidazo[1,2-...)
Show SMILES COCC(=O)N(C)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C19H18BrCl2N3O3/c1-11-18(20)25-8-4-5-15(19(25)23-11)28-9-12-13(21)6-7-14(17(12)22)24(2)16(26)10-27-3/h4-8H,9-10H2,1-3H3
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n/an/a 580n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062876
PNG
(CHEMBL545573 | N-[3-(3-Bromo-2-methyl-imidazo[1,2-...)
Show SMILES CN(C(=O)CNS(C)(=O)=O)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C19H19BrCl2N4O4S/c1-11-18(20)26-8-4-5-15(19(26)24-11)30-10-12-13(21)6-7-14(17(12)22)25(2)16(27)9-23-31(3,28)29/h4-8,23H,9-10H2,1-3H3
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n/an/a 580n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062903
PNG
(2-Acetylamino-N-[3-(3-bromo-2-methyl-imidazo[1,2-a...)
Show SMILES CC(NC(C)=O)C(=O)N(C)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C21H21BrCl2N4O3/c1-11-19(22)28-9-5-6-17(20(28)26-11)31-10-14-15(23)7-8-16(18(14)24)27(4)21(30)12(2)25-13(3)29/h5-9,12H,10H2,1-4H3,(H,25,29)
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n/an/a 770n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062889
PNG
(3-Acetylamino-N-[3-(3-bromo-2-methyl-imidazo[1,2-a...)
Show SMILES CN(C(=O)CCNC(C)=O)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C21H21BrCl2N4O3/c1-12-20(22)28-10-4-5-17(21(28)26-12)31-11-14-15(23)6-7-16(19(14)24)27(3)18(30)8-9-25-13(2)29/h4-7,10H,8-9,11H2,1-3H3,(H,25,29)
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n/an/a 810n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062881
PNG
((3-Chloro-2-methyl-imidazo[1,2-a]pyridin-8-yl)-(2,...)
Show SMILES Cc1nc2c(NCc3c(Cl)cccc3Cl)cccn2c1Cl
Show InChI InChI=1S/C15H12Cl3N3/c1-9-14(18)21-7-3-6-13(15(21)20-9)19-8-10-11(16)4-2-5-12(10)17/h2-7,19H,8H2,1H3
MMDB

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n/an/a 1.20E+3n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062869
PNG
(CHEMBL152650 | [3-(3-Bromo-2-methyl-imidazo[1,2-a]...)
Show SMILES COC(=O)N(C)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C18H16BrCl2N3O3/c1-10-16(19)24-8-4-5-14(17(24)22-10)27-9-11-12(20)6-7-13(15(11)21)23(2)18(25)26-3/h4-8H,9H2,1-3H3
MMDB

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n/an/a 1.40E+3n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062885
PNG
(3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxym...)
Show SMILES Cc1nc2c(OCc3c(Cl)ccc(N)c3Cl)cccn2c1Br
Show InChI InChI=1S/C15H12BrCl2N3O/c1-8-14(16)21-6-2-3-12(15(21)20-8)22-7-9-10(17)4-5-11(19)13(9)18/h2-6H,7,19H2,1H3
MMDB

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n/an/a 1.50E+3n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062882
PNG
(3-Bromo-8-(2-chloro-6-fluoro-benzyloxy)-2-methyl-i...)
Show SMILES Cc1nc2c(OCc3c(F)cccc3Cl)cccn2c1Br
Show InChI InChI=1S/C15H11BrClFN2O/c1-9-14(16)20-7-3-6-13(15(20)19-9)21-8-10-11(17)4-2-5-12(10)18/h2-7H,8H2,1H3
MMDB

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n/an/a 1.50E+3n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062892
PNG
(2-(Acetyl-methyl-amino)-N-[3-(3-bromo-2-methyl-imi...)
Show SMILES CN(CC(=O)N(C)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl)C(C)=O
Show InChI InChI=1S/C21H21BrCl2N4O3/c1-12-20(22)28-9-5-6-17(21(28)25-12)31-11-14-15(23)7-8-16(19(14)24)27(4)18(30)10-26(3)13(2)29/h5-9H,10-11H2,1-4H3
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n/an/a 1.60E+3n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062862
PNG
(3-Chloro-8-(2,6-dibromo-benzyloxy)-2-methyl-imidaz...)
Show SMILES Cc1nc2c(OCc3c(Br)cccc3Br)cccn2c1Cl
Show InChI InChI=1S/C15H11Br2ClN2O/c1-9-14(18)20-7-3-6-13(15(20)19-9)21-8-10-11(16)4-2-5-12(10)17/h2-7H,8H2,1H3
MMDB

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n/an/a 1.70E+3n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062873
PNG
(CHEMBL154558 | N-[3-(3-Bromo-2-methyl-imidazo[1,2-...)
Show SMILES CC(=O)Nc1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl
Show InChI InChI=1S/C17H14BrCl2N3O2/c1-9-16(18)23-7-3-4-14(17(23)21-9)25-8-11-12(19)5-6-13(15(11)20)22-10(2)24/h3-7H,8H2,1-2H3,(H,22,24)
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n/an/a 1.80E+3n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062870
PNG
(3-Chloro-8-(2,6-difluoro-benzyloxy)-2-methyl-imida...)
Show SMILES Cc1nc2c(OCc3c(F)cccc3F)cccn2c1Cl
Show InChI InChI=1S/C15H11ClF2N2O/c1-9-14(16)20-7-3-6-13(15(20)19-9)21-8-10-11(17)4-2-5-12(10)18/h2-7H,8H2,1H3
MMDB

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n/an/a 1.80E+3n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062894
PNG
(CHEMBL152158 | N-[3-(3-Bromo-2-methyl-imidazo[1,2-...)
Show SMILES CN(c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl)S(C)(=O)=O
Show InChI InChI=1S/C17H16BrCl2N3O3S/c1-10-16(18)23-8-4-5-14(17(23)21-10)26-9-11-12(19)6-7-13(15(11)20)22(2)27(3,24)25/h4-8H,9H2,1-3H3
MMDB

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n/an/a 2.10E+3n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062866
PNG
(8-(2,6-Dichloro-benzyloxy)-2-methyl-imidazo[1,2-a]...)
Show SMILES Cc1cn2cccc(OCc3c(Cl)cccc3Cl)c2n1
Show InChI InChI=1S/C15H12Cl2N2O/c1-10-8-19-7-3-6-14(15(19)18-10)20-9-11-12(16)4-2-5-13(11)17/h2-8H,9H2,1H3
MMDB

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n/an/a 4.50E+3n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062900
PNG
(CHEMBL153890 | [8-(2,6-Dichloro-benzyloxy)-2-methy...)
Show SMILES Cc1nc2c(OCc3c(Cl)cccc3Cl)cccn2c1CO
Show InChI InChI=1S/C16H14Cl2N2O2/c1-10-14(8-21)20-7-3-6-15(16(20)19-10)22-9-11-12(17)4-2-5-13(11)18/h2-7,21H,8-9H2,1H3
MMDB

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n/an/a 7.50E+3n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062902
PNG
(8-(2,6-Dichloro-benzyloxy)-2-methyl-3-prop-2-ynylo...)
Show SMILES Cc1nc2c(OCc3c(Cl)cccc3Cl)cccn2c1COCC#C
Show InChI InChI=1S/C19H16Cl2N2O2/c1-3-10-24-12-17-13(2)22-19-18(8-5-9-23(17)19)25-11-14-15(20)6-4-7-16(14)21/h1,4-9H,10-12H2,2H3
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n/an/a 7.60E+3n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062872
PNG
(8-(2,6-Dichloro-benzyloxy)-2-ethyl-imidazo[1,2-a]p...)
Show SMILES CCc1cn2cccc(OCc3c(Cl)cccc3Cl)c2n1
Show InChI InChI=1S/C16H14Cl2N2O/c1-2-11-9-20-8-4-7-15(16(20)19-11)21-10-12-13(17)5-3-6-14(12)18/h3-9H,2,10H2,1H3
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n/an/a 1.00E+4n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062877
PNG
(8-(2,6-Dichloro-benzyloxy)-imidazo[1,2-a]pyridine ...)
Show SMILES Clc1cccc(Cl)c1COc1cccn2ccnc12
Show InChI InChI=1S/C14H10Cl2N2O/c15-11-3-1-4-12(16)10(11)9-19-13-5-2-7-18-8-6-17-14(13)18/h1-8H,9H2
MMDB

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n/an/a 3.10E+4n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062904
PNG
(1-Ethyl-5-methyl-2-[4-(2-methyl-quinolin-4-yloxyme...)
Show SMILES CCn1c(C)cc(C#N)c1-c1ccc(COc2cc(C)nc3ccccc23)cc1
Show InChI InChI=1S/C25H23N3O/c1-4-28-18(3)14-21(15-26)25(28)20-11-9-19(10-12-20)16-29-24-13-17(2)27-23-8-6-5-7-22(23)24/h5-14H,4,16H2,1-3H3
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n/an/a 3.10E+4n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062895
PNG
(CHEMBL154158 | N-(3-Bromo-2-methyl-imidazo[1,2-a]p...)
Show SMILES CC(=O)N(Cc1c(Cl)cccc1Cl)c1cccn2c(Br)c(C)nc12
Show InChI InChI=1S/C17H14BrCl2N3O/c1-10-16(18)22-8-4-7-15(17(22)21-10)23(11(2)24)9-12-13(19)5-3-6-14(12)20/h3-8H,9H2,1-2H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062880
PNG
(2,6-Dichloro-N-(3-chloro-2-methyl-imidazo[1,2-a]py...)
Show SMILES Cc1nc2c(NC(=O)c3c(Cl)cccc3Cl)cccn2c1Cl
Show InChI InChI=1S/C15H10Cl3N3O/c1-8-13(18)21-7-3-6-11(14(21)19-8)20-15(22)12-9(16)4-2-5-10(12)17/h2-7H,1H3,(H,20,22)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062861
PNG
(3-Bromo-8-[(E)-2-(2,6-dichloro-phenyl)-vinyl]-2-me...)
Show SMILES Cc1nc2c(\C=C\c3c(Cl)cccc3Cl)cccn2c1Br
Show InChI InChI=1S/C16H11BrCl2N2/c1-10-15(17)21-9-3-4-11(16(21)20-10)7-8-12-13(18)5-2-6-14(12)19/h2-9H,1H3/b8-7+
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n/an/a>1.00E+5n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062896
PNG
(8-(2,6-Dichloro-benzyloxy)-2-methyl-imidazo[1,2-a]...)
Show SMILES CCOC(=O)c1c(C)nc2c(OCc3c(Cl)cccc3Cl)cccn12
Show InChI InChI=1S/C18H16Cl2N2O3/c1-3-24-18(23)16-11(2)21-17-15(8-5-9-22(16)17)25-10-12-13(19)6-4-7-14(12)20/h4-9H,3,10H2,1-2H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062887
PNG
(3-Bromo-8-(2,6-dichloro-phenoxymethyl)-2-methyl-im...)
Show SMILES Cc1nc2c(COc3c(Cl)cccc3Cl)cccn2c1Br
Show InChI InChI=1S/C15H11BrCl2N2O/c1-9-14(16)20-7-3-4-10(15(20)19-9)8-21-13-11(17)5-2-6-12(13)18/h2-7H,8H2,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062875
PNG
(3-Bromo-2-methyl-imidazo[1,2-a]pyridine-8-carboxyl...)
Show SMILES Cc1nc2c(cccn2c1Br)C(=O)Oc1c(Cl)cccc1Cl
Show InChI InChI=1S/C15H9BrCl2N2O2/c1-8-13(16)20-7-3-4-9(14(20)19-8)15(21)22-12-10(17)5-2-6-11(12)18/h2-7H,1H3
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n/an/a>1.00E+5n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062897
PNG
(3-Bromo-2-methyl-imidazo[1,2-a]pyridine-8-carboxyl...)
Show SMILES Cc1nc2c(cccn2c1Br)C(=O)Nc1c(Cl)cccc1Cl
Show InChI InChI=1S/C15H10BrCl2N3O/c1-8-13(16)21-7-3-4-9(14(21)19-8)15(22)20-12-10(17)5-2-6-11(12)18/h2-7H,1H3,(H,20,22)
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n/an/a>1.00E+5n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
Bradykinin B2 receptor


(Cavia porcellus)
BDBM50062874
PNG
(8-(2,6-Dichloro-benzyloxy)-2-trifluoromethyl-imida...)
Show SMILES FC(F)(F)c1cn2cccc(OCc3c(Cl)cccc3Cl)c2n1
Show InChI InChI=1S/C15H9Cl2F3N2O/c16-10-3-1-4-11(17)9(10)8-23-12-5-2-6-22-7-13(15(18,19)20)21-14(12)22/h1-7H,8H2
MMDB

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n/an/a>1.00E+5n/an/an/an/an/an/a



Fujisawa Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro for inhibition of specific binding of [3H]BK (0.06 nM) to bradykinin receptor B2 in guinea pig ileum membrane preparations.


J Med Chem 41: 564-78 (1998)


Article DOI: 10.1021/jm970591c
BindingDB Entry DOI: 10.7270/Q2445N6P
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%