Compile Data Set for Download or QSAR
maximum 50k data
Found 21 Enz. Inhib. hit(s) with all data for entry = 50007447
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50063477((3S,10R,13S)-17-Imidazol-1-yl-10,13-dimethyl-2,3,4...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity for Cytochrome P450 17A1 (17-alpha-hydroxypregnenolone Km=560 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50063476((3S,10R,13S)-10,13-Dimethyl-17-[1,2,3]triazol-1-yl...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity for Cytochrome P450 17A1 (17-alpha-hydroxypregnenolone Km=560 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50063475((10R,13S)-17-Imidazol-1-yl-10,13-dimethyl-1,2,6,7,...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity for Cytochrome P450 17A1 (17-alpha-hydroxypregnenolone Km=560 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50063479((10R,13S)-10,13-Dimethyl-17-[1,2,3]triazol-1-yl-1,...)
Affinity DataKi:  8nMAssay Description:Binding affinity for Cytochrome P450 17A1 (17-alpha-hydroxypregnenolone Km=560 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50063480((3S,10R,13S)-10,13-Dimethyl-17-[1,2,4]triazol-1-yl...)
Affinity DataKi:  23nMAssay Description:Binding affinity for Cytochrome P450 17A1 (17-alpha-hydroxypregnenolone Km=560 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataKi:  38nMAssay Description:Binding affinity for Cytochrome P450 17A1 (17-alpha-hydroxypregnenolone Km=560 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50063478((10R,13S)-10,13-Dimethyl-17-[1,2,4]triazol-1-yl-1,...)
Affinity DataKi:  41nMAssay Description:Binding affinity for Cytochrome P450 17A1 (17-alpha-hydroxypregnenolone Km=560 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50063475((10R,13S)-17-Imidazol-1-yl-10,13-dimethyl-1,2,6,7,...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human testicular microsomal Cytochrome P450 17A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50063475((10R,13S)-17-Imidazol-1-yl-10,13-dimethyl-1,2,6,7,...)
Affinity DataIC50:  8nMAssay Description:Inhibition of rat Cytochrome P450 17A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50063477((3S,10R,13S)-17-Imidazol-1-yl-10,13-dimethyl-2,3,4...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human testicular microsomal Cytochrome P450 17A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50063477((3S,10R,13S)-17-Imidazol-1-yl-10,13-dimethyl-2,3,4...)
Affinity DataIC50:  9nMAssay Description:Inhibition of rat Cytochrome P450 17A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50063479((10R,13S)-10,13-Dimethyl-17-[1,2,3]triazol-1-yl-1,...)
Affinity DataIC50:  9nMAssay Description:Inhibition of rat cytochrome P450 17A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50063476((3S,10R,13S)-10,13-Dimethyl-17-[1,2,3]triazol-1-yl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of rat Cytochrome P450 17A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50063478((10R,13S)-10,13-Dimethyl-17-[1,2,4]triazol-1-yl-1,...)
Affinity DataIC50:  11nMAssay Description:Inhibition of rat Cytochrome P450 17A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50063476((3S,10R,13S)-10,13-Dimethyl-17-[1,2,3]triazol-1-yl...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human testicular microsomal Cytochrome P450 17A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50063479((10R,13S)-10,13-Dimethyl-17-[1,2,3]triazol-1-yl-1,...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human testicular microsomal Cytochrome P450 17A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50063480((3S,10R,13S)-10,13-Dimethyl-17-[1,2,4]triazol-1-yl...)
Affinity DataIC50:  26nMAssay Description:Inhibition of rat cytochrome P450 17A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50063478((10R,13S)-10,13-Dimethyl-17-[1,2,4]triazol-1-yl-1,...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human testicular microsomal Cytochrome P450 17A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  78nMAssay Description:Inhibition of human testicular microsomal Cytochrome P450 17A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50063480((3S,10R,13S)-10,13-Dimethyl-17-[1,2,4]triazol-1-yl...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human testicular microsomal Cytochrome P450 17A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  209nMAssay Description:Inhibition of rat Cytochrome P450 17A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed