Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 50007572
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064797((3R,6S)-6-Cyclohexylmethyl-3-mercaptomethyl-1-(4-m...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Matrix Metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064794((3R,6S)-6-Cyclohexylmethyl-3-mercaptomethyl-1-quin...)
Affinity DataIC50:  35nMAssay Description:Inhibition of Matrix Metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064792((3R,6S)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50:  47nMAssay Description:Inhibition of collagenase-1 (Matrix metalloproteinase-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064792((3R,6S)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50:  47nMAssay Description:Inhibition of Matrix Metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064798((3R,6S)-6-Benzyl-3-mercaptomethyl-1-(4-methoxy-ben...)
Affinity DataIC50:  64nMAssay Description:Inhibition of Matrix Metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064797((3R,6S)-6-Cyclohexylmethyl-3-mercaptomethyl-1-(4-m...)
Affinity DataIC50:  79nMAssay Description:Inhibition of Matrix Metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064794((3R,6S)-6-Cyclohexylmethyl-3-mercaptomethyl-1-quin...)
Affinity DataIC50:  87nMAssay Description:Inhibition of Matrix Metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064792((3R,6S)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50:  113nMAssay Description:Inhibition of gelatinase-B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064792((3R,6S)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50:  121nMAssay Description:Inhibition of Matrix Metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064796((3R,6S)-6-Butyl-1-cyclohexylmethyl-3-mercaptomethy...)
Affinity DataIC50:  220nMAssay Description:Inhibition of Matrix Metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064795((3R,6S)-6-Benzyl-1-butyl-3-mercaptomethyl-piperazi...)
Affinity DataIC50:  319nMAssay Description:Inhibition of Matrix Metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064796((3R,6S)-6-Butyl-1-cyclohexylmethyl-3-mercaptomethy...)
Affinity DataIC50:  370nMAssay Description:Inhibition of Matrix Metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064792((3R,6S)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50:  590nMAssay Description:Inhibition of matrilysin (Matrix metalloproteinase-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064791((3R,6R)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of collagenase-1 (Matrix metalloproteinase-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064793((3S,6S)-1-Hexyl-6-mercaptomethyl-3-pyridin-3-ylmet...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of collagenase-1 (Matrix metalloproteinase-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064792((3R,6S)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of stromelysin (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064795((3R,6S)-6-Benzyl-1-butyl-3-mercaptomethyl-piperazi...)
Affinity DataIC50:  2.37E+3nMAssay Description:Inhibition of Matrix Metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064798((3R,6S)-6-Benzyl-3-mercaptomethyl-1-(4-methoxy-ben...)
Affinity DataIC50:  2.37E+3nMAssay Description:Inhibition of Matrix Metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064794((3R,6S)-6-Cyclohexylmethyl-3-mercaptomethyl-1-quin...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of Matrix Metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064790((3S,6S)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of collagenase-1 (Matrix metalloproteinase-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064792((3R,6S)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50:  2.91E+3nMAssay Description:Inhibition of Matrix Metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064796((3R,6S)-6-Butyl-1-cyclohexylmethyl-3-mercaptomethy...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of Matrix Metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064797((3R,6S)-6-Cyclohexylmethyl-3-mercaptomethyl-1-(4-m...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of Matrix Metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064798((3R,6S)-6-Benzyl-3-mercaptomethyl-1-(4-methoxy-ben...)
Affinity DataIC50:  4.05E+3nMAssay Description:Inhibition of Matrix Metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064791((3R,6R)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of matrilysin (Matrix metalloproteinase-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064790((3S,6S)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of gelatinase-B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064799((3S,6S)-6-Mercaptomethyl-1-octyl-3-pyridin-3-ylmet...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of collagenase-1 (Matrix metalloproteinase-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064791((3R,6R)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of gelatinase-B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064789((3S,6R)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of collagenase-1 (Matrix metalloproteinase-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064795((3R,6S)-6-Benzyl-1-butyl-3-mercaptomethyl-piperazi...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of Matrix Metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064789((3S,6R)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of matrilysin (Matrix metalloproteinase-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064791((3R,6R)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of stromelysin-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064790((3S,6S)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of stromelysin (Matrix metalloproteinase-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064789((3S,6R)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of gelatinase-B (Matrix metalloproteinase-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064790((3S,6S)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of matrilysin (Matrix metalloproteinase-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50064789((3S,6R)-1,6-Bis-cyclohexylmethyl-3-mercaptomethyl-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of stromelysin-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed