Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 50007871
TargetSqualene synthase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50038096((6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-...)
Affinity DataIC50:  12nMAssay Description:Compound was tested for inhibition of squalene synthase from rat liver microsomes using [3H]-Farnesyl pyrophosphate (FPP) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50058945((1S,2S,3S,4S)-3,4-Bis-[(4-phenoxy-benzyl)-propyl-c...)
Affinity DataIC50:  37nMAssay Description:Compound was tested for inhibition of squalene synthase from rat liver microsomes using [3H]-Farnesyl pyrophosphate (FPP) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50068843((1S,2S,3S,5S)-3,5-Bis-[(4-phenoxy-benzyl)-propyl-c...)
Affinity DataIC50:  170nMAssay Description:Compound was tested for inhibition of squalene synthase from rat liver microsomes using [3H]-Farnesyl pyrophosphate (FPP) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50068845((1S,2S,3S,5R)-1-Carboxymethyl-3,5-bis-[(4-phenoxy-...)
Affinity DataIC50:  240nMAssay Description:Compound was tested for inhibition of squalene synthase from rat liver microsomes using [3H]-Farnesyl pyrophosphate (FPP) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50068842((1S,2S,3S,5R)-3,5-Bis-[(4-phenoxy-benzyl)-propyl-c...)
Affinity DataIC50:  580nMAssay Description:Compound was tested for inhibition of squalene synthase from rat liver microsomes using [3H]-Farnesyl pyrophosphate (FPP) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50068844((1R,2R,3S,4S)-2,4-Bis-[(4-phenoxy-benzyl)-propyl-c...)
Affinity DataIC50:  2.90E+3nMAssay Description:Compound was tested for inhibition of squalene synthase from rat liver microsomes using [3H]-Farnesyl pyrophosphate (FPP) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50068846((2R,3R,4S,5S)-4,5-Bis-[(4-phenoxy-benzyl)-propyl-c...)
Affinity DataIC50:  3.00E+3nMAssay Description:Compound was tested for inhibition of squalene synthase from rat liver microsomes using [3H]-Farnesyl pyrophosphate (FPP) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50068841((1S,3R,4S,5R)-4,5-Bis-[(4-phenoxy-benzyl)-propyl-c...)
Affinity DataIC50:  9.10E+3nMAssay Description:Compound was tested for inhibition of squalene synthase from rat liver microsomes using [3H]-Farnesyl pyrophosphate (FPP) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed