Compile Data Set for Download or QSAR
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Found 13 Enz. Inhib. hit(s) with all data for entry = 50008213
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071565(2-(2,2-Diphenyl-ethyl)-7-methyl-1,3-dioxo-2,3,5,8-...)
Affinity DataKi:  0.0350nMAssay Description:Compound was evaluated for its binding affinity to the thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071575(2,2-Dibutyl-7-methyl-1,3-dioxo-2,3,5,8-tetrahydro-...)
Affinity DataKi:  0.200nMAssay Description:Compound was evaluated for its binding affinity to the thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071570(8-Isobutyl-2-(4-methoxy-phenyl)-1,3-dioxo-2,3,5,8-...)
Affinity DataKi:  0.280nMAssay Description:Compound was evaluated for its binding affinity to the trypsin enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071573(2-(2,2-Diphenyl-ethyl)-1,3-dioxo-2,3,5,8-tetrahydr...)
Affinity DataKi:  0.300nMAssay Description:Compound was evaluated for its binding affinity to the thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071571(8-Isobutyl-2-(3-methyl-butyl)-1,3-dioxo-2,3,5,8-te...)
Affinity DataKi:  0.430nMAssay Description:Compound was evaluated for its binding affinity to the trypsin enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071568(2-Amino-2-benzyl-7-methyl-1,3-dioxo-2,3,5,8-tetrah...)
Affinity DataKi:  1.60nMAssay Description:Compound was evaluated for its binding affinity to the thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071567(2,2-Dibenzyl-7-methyl-1,3-dioxo-2,3,5,8-tetrahydro...)
Affinity DataKi:  1.90nMAssay Description:Compound was evaluated for its binding affinity to the thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071566(2-Amino-8-benzyl-2-ethyl-1,3-dioxo-2,3,5,8-tetrahy...)
Affinity DataKi:  4.30nMAssay Description:Compound was evaluated for its binding affinity to the thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071574(2,2-Diisobutyl-7-methyl-1,3-dioxo-2,3,5,8-tetrahyd...)
Affinity DataKi:  5.10nMAssay Description:Compound was evaluated for its binding affinity to the thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2/delta/gamma(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50216213(CHEMBL306744)
Affinity DataKi:  5.90nMAssay Description:Compound was evaluated for its binding affinity to the tryptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071564(2,2-Diallyl-7-methyl-1,3-dioxo-2,3,5,8-tetrahydro-...)
Affinity DataKi:  18nMAssay Description:Compound was evaluated for its binding affinity to the thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071572(8-{5-Amino-1-[2-(4-carbamoyl-phenyl)-ethylaminooxa...)
Affinity DataKi:  21nMAssay Description:Compound was evaluated for its inhibitory activity against KallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Molecumetics

Curated by ChEMBL
LigandPNGBDBM50071563(4-(2-{6-amino-2-[7-(3,4-dichlorobenzyl)-13,13-dime...)
Affinity DataKi:  31nMAssay Description:Compound was evaluated for its inhibitory activity against KallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed