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Found 15 Enz. Inhib. hit(s) with all data for entry = 50048444
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)
Affinity DataKi:  1nMAssay Description:Inhibition of Rolipram binding to Phosphodiesterase 4More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of Phosphodiesterase 4 (PDE4) from guinea pig macrophagesMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of PDE4 from guinea pig macrophagesMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50216232(CHEMBL93823)
Affinity DataIC50:  2nMAssay Description:Inhibition of PDE4 from guinea pig macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50216233(CHEMBL330055)
Affinity DataIC50:  23nMAssay Description:Inhibition of PDE4 from guinea pig macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50216234(CHEMBL89931)
Affinity DataIC50:  25nMAssay Description:Inhibition of PDE4 from guinea pig macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50216229(CHEMBL329556)
Affinity DataIC50:  27nMAssay Description:Inhibition of PDE4 from guinea pig macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50216293(CHEMBL94009)
Affinity DataIC50:  28nMAssay Description:Inhibition of Phosphodiesterase 4 (PDE4) from guinea pig macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50216294(CHEMBL449708)
Affinity DataIC50:  42nMAssay Description:Inhibition of PDE4 from guinea pig macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50216228(CHEMBL94255)
Affinity DataIC50:  45nMAssay Description:Inhibition of Phosphodiesterase 4 (PDE4) from guinea pig macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50216231(CHEMBL329155)
Affinity DataIC50:  100nMAssay Description:Inhibition of PDE4 from guinea pig macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50216230(CHEMBL93327)
Affinity DataIC50:  450nMAssay Description:Inhibition of PDE4 from guinea pig macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM23620(2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Phosphodiesterase 4 (PDE4) from guinea pig macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50216227(CHEMBL329365)
Affinity DataIC50:  540nMAssay Description:Inhibition of PDE4 from guinea pig macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50216226(CHEMBL329023)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of PDE4 from guinea pig macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed