Compile Data Set for Download or QSAR
maximum 50k data
Found 42 Enz. Inhib. hit(s) with all data for entry = 1386
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319770(US10174013, Example 1AE)
Affinity DataIC50:  400nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319772(US10174013, Example 1AI)
Affinity DataIC50:  440nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319757(US10174013, Example 1M)
Affinity DataIC50:  520nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319786(US10174013, Example 1BM)
Affinity DataIC50:  740nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319753(US10174013, Example 8A)
Affinity DataIC50:  770nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319755(US10174013, Example 22A | US10174013, Example 22AB...)
Affinity DataIC50:  850nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319779(US10174013, Example 1AX)
Affinity DataIC50:  1.23E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319758(US10174013, Example 1N)
Affinity DataIC50:  1.28E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319769(US10174013, Example 1AD)
Affinity DataIC50:  1.42E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319774(US10174013, Example 1AM)
Affinity DataIC50:  1.46E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319752(US10174013, Example 1A | US10174013, Example 1X | ...)
Affinity DataIC50:  1.60E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319759(US10174013, Example 2A | US10174013, Example 2C | ...)
Affinity DataIC50:  1.60E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319755(US10174013, Example 22A | US10174013, Example 22AB...)
Affinity DataIC50:  1.78E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319775(US10174013, Example 1AP)
Affinity DataIC50:  1.82E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319768(US10174013, Example 1AC)
Affinity DataIC50:  1.86E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319776(US10174013, Example 1AQ)
Affinity DataIC50:  1.86E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319760(US10174013, Example 1P)
Affinity DataIC50:  1.88E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319781(US10174013, Example 1AZ)
Affinity DataIC50:  1.88E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319755(US10174013, Example 22A | US10174013, Example 22AB...)
Affinity DataIC50:  2.02E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319765(US10174013, Example 1AA)
Affinity DataIC50:  2.27E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319773(US10174013, Example 1AL)
Affinity DataIC50:  2.42E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319759(US10174013, Example 2A | US10174013, Example 2C | ...)
Affinity DataIC50:  2.50E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319759(US10174013, Example 2A | US10174013, Example 2C | ...)
Affinity DataIC50:  3.06E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319780(US10174013, Example 1AY)
Affinity DataIC50:  3.88E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319777(US10174013, Example 1AR)
Affinity DataIC50:  4.17E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319784(US10174013, Example 1BD)
Affinity DataIC50:  4.34E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319771(US10174013, Example 1AH)
Affinity DataIC50:  4.99E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319783(US10174013, Example 1BI)
Affinity DataIC50:  5.17E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319778(US10174013, Example 1AS)
Affinity DataIC50:  5.77E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319767(US10174013, Example 1AB)
Affinity DataIC50:  8.93E+3nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319755(US10174013, Example 22A | US10174013, Example 22AB...)
Affinity DataIC50:  1.01E+4nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319755(US10174013, Example 22A | US10174013, Example 22AB...)
Affinity DataIC50:  1.19E+4nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319752(US10174013, Example 1A | US10174013, Example 1X | ...)
Affinity DataIC50:  1.69E+4nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319752(US10174013, Example 1A | US10174013, Example 1X | ...)
Affinity DataIC50:  2.04E+4nMAssay Description:The hERG (human ether-A-go-go-related gene) channel corresponds to an important anti-target for potential new drugs since its inhibition may lead to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319787(5,6-dibromo-4-nitro-2-(piperazin-1-yl)-1-(propan-2...)
Affinity DataKd:  130nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319787(5,6-dibromo-4-nitro-2-(piperazin-1-yl)-1-(propan-2...)
Affinity DataKd:  18nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3 [D835H](Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319787(5,6-dibromo-4-nitro-2-(piperazin-1-yl)-1-(propan-2...)
Affinity DataKd:  28nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3 [D835Y](Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319752(US10174013, Example 1A | US10174013, Example 1X | ...)
Affinity DataKd:  46nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3 [D835H](Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319752(US10174013, Example 1A | US10174013, Example 1X | ...)
Affinity DataKd:  120nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319752(US10174013, Example 1A | US10174013, Example 1X | ...)
Affinity DataKd:  400nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3 [D835Y](Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319787(5,6-dibromo-4-nitro-2-(piperazin-1-yl)-1-(propan-2...)
Affinity DataKd:  15nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Selvita

US Patent
LigandPNGBDBM319752(US10174013, Example 1A | US10174013, Example 1X | ...)
Affinity DataKd:  74nMAssay Description:Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent