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Found 9 Enz. Inhib. hit(s) with all data for entry = 6257
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM119778(CHEMBL2180429 | US8691827, I-9)
Affinity DataKi:  2.19nMAssay Description:The PDE10 Ki is a measure of the ability of the test compound to inhibit the action of the PDE10 enzyme. The final product may be further modified, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50398005(CHEMBL2180430 | US8691827, I-8)
Affinity DataKi:  15nMAssay Description:The PDE10 Ki is a measure of the ability of the test compound to inhibit the action of the PDE10 enzyme. The final product may be further modified, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50398007(CHEMBL2180428 | US8691827, I-1)
Affinity DataKi:  47.9nMAssay Description:The PDE10 Ki is a measure of the ability of the test compound to inhibit the action of the PDE10 enzyme. The final product may be further modified, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM119777(US8691827, I-7)
Affinity DataKi:  63nMAssay Description:The PDE10 Ki is a measure of the ability of the test compound to inhibit the action of the PDE10 enzyme. The final product may be further modified, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM119775(US8691827, I-5)
Affinity DataKi:  95.3nMAssay Description:The PDE10 Ki is a measure of the ability of the test compound to inhibit the action of the PDE10 enzyme. The final product may be further modified, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM119776(US8691827, I-6)
Affinity DataKi:  114nMAssay Description:The PDE10 Ki is a measure of the ability of the test compound to inhibit the action of the PDE10 enzyme. The final product may be further modified, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM119774(US8691827, I-4)
Affinity DataKi:  153nMAssay Description:The PDE10 Ki is a measure of the ability of the test compound to inhibit the action of the PDE10 enzyme. The final product may be further modified, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM119773(US8691827, I-3)
Affinity DataKi:  162nMAssay Description:The PDE10 Ki is a measure of the ability of the test compound to inhibit the action of the PDE10 enzyme. The final product may be further modified, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM119772(US8691827, I-2)
Affinity DataKi:  192nMAssay Description:The PDE10 Ki is a measure of the ability of the test compound to inhibit the action of the PDE10 enzyme. The final product may be further modified, ...More data for this Ligand-Target Pair
In DepthDetails US Patent