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Found 8 Enz. Inhib. hit(s) with all data for entry = 6534
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services

US Patent
LigandPNGBDBM136689(US8865686, Table 1, Compound 2)
Affinity DataIC50:  9.00E+3nMpH: 8.0 T: 2°CAssay Description:Assay: Unless indicated otherwise, Tdp1 assays were performed in 20 ul mixtures containing 50 mM Tris-HCl, pH 8.0, 80 mM KCl, 2 mM EDTA, 1 mM dithiot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services

US Patent
LigandPNGBDBM136691(US8865686, Table 1, Compound 3)
Affinity DataIC50:  2.90E+4nMpH: 8.0 T: 2°CAssay Description:Assay: Unless indicated otherwise, Tdp1 assays were performed in 20 ul mixtures containing 50 mM Tris-HCl, pH 8.0, 80 mM KCl, 2 mM EDTA, 1 mM dithiot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services

US Patent
LigandPNGBDBM136692(US8865686, Table 1, Compound 4)
Affinity DataIC50:  4.90E+4nMpH: 8.0 T: 2°CAssay Description:Assay: Unless indicated otherwise, Tdp1 assays were performed in 20 ul mixtures containing 50 mM Tris-HCl, pH 8.0, 80 mM KCl, 2 mM EDTA, 1 mM dithiot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services

US Patent
LigandPNGBDBM136693(US8865686, Table 1, Compound 5)
Affinity DataIC50:  8.40E+4nMpH: 8.0 T: 2°CAssay Description:Assay: Unless indicated otherwise, Tdp1 assays were performed in 20 ul mixtures containing 50 mM Tris-HCl, pH 8.0, 80 mM KCl, 2 mM EDTA, 1 mM dithiot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services

US Patent
LigandPNGBDBM136694(US8865686, Table 1, Compound 6)
Affinity DataIC50:  1.06E+5nMpH: 8.0 T: 2°CAssay Description:Assay: Unless indicated otherwise, Tdp1 assays were performed in 20 ul mixtures containing 50 mM Tris-HCl, pH 8.0, 80 mM KCl, 2 mM EDTA, 1 mM dithiot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services

US Patent
LigandPNGBDBM136695(US8865686, Table 1, Compound 7)
Affinity DataIC50:  1.22E+5nMpH: 8.0 T: 2°CAssay Description:Assay: Unless indicated otherwise, Tdp1 assays were performed in 20 ul mixtures containing 50 mM Tris-HCl, pH 8.0, 80 mM KCl, 2 mM EDTA, 1 mM dithiot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services

US Patent
LigandPNGBDBM136696(US8865686, Table 1, Compound 8)
Affinity DataIC50:  1.41E+5nMpH: 8.0 T: 2°CAssay Description:Assay: Unless indicated otherwise, Tdp1 assays were performed in 20 ul mixtures containing 50 mM Tris-HCl, pH 8.0, 80 mM KCl, 2 mM EDTA, 1 mM dithiot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services

US Patent
LigandPNGBDBM136690(US8865686, Table 1, Compound 1)
Affinity DataIC50:  7.85E+5nMpH: 8.0 T: 2°CAssay Description:Assay: Unless indicated otherwise, Tdp1 assays were performed in 20 ul mixtures containing 50 mM Tris-HCl, pH 8.0, 80 mM KCl, 2 mM EDTA, 1 mM dithiot...More data for this Ligand-Target Pair
In DepthDetails US Patent