Compile Data Set for Download or QSAR
maximum 50k data
Found 175 Enz. Inhib. hit(s) with all data for entry = 6615
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM50397942(CHEMBL2179534)
Affinity DataKi:  1.5nM ΔG°:  -49.7kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM50397942(CHEMBL2179534)
Affinity DataKi:  1.5nM ΔG°:  -49.7kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM141885(US8921410, Table 2 Compound 20)
Affinity DataKi:  1.60nM ΔG°:  -49.5kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM50397929(CHEMBL2179547)
Affinity DataKi:  1.70nM ΔG°:  -49.4kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM50397888(CHEMBL2179531)
Affinity DataKi:  2.40nM ΔG°:  -48.5kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM50397888(CHEMBL2179531)
Affinity DataKi:  2.80nM ΔG°:  -48.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM141885(US8921410, Table 2 Compound 20)
Affinity DataKi:  4nM ΔG°:  -47.3kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM50397936(CHEMBL2179540)
Affinity DataKi:  4.60nM ΔG°:  -46.9kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM141867(US8921410, Table 1 Compound 33)
Affinity DataKi:  4.90nM ΔG°:  -46.8kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM50397932(CHEMBL2179544)
Affinity DataKi:  5.20nM ΔG°:  -46.6kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM141887(US8921410, Table 2 Compound 25)
Affinity DataKi:  5.20nM ΔG°:  -46.6kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM141875(US8921410, Table 2 Compound 8)
Affinity DataKi:  5.90nM ΔG°:  -46.3kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM141883(US8921410, Table 2 Compound 18)
Affinity DataKi:  6.30nM ΔG°:  -46.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM50397936(CHEMBL2179540)
Affinity DataKi:  6.40nM ΔG°:  -46.1kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM50397933(CHEMBL2179543)
Affinity DataKi:  7.30nM ΔG°:  -45.8kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM141887(US8921410, Table 2 Compound 25)
Affinity DataKi:  7.5nM ΔG°:  -45.8kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM50397893(CHEMBL2179526)
Affinity DataKi:  8.30nM ΔG°:  -45.5kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM141891(US8921410, Table 2 Compound 30)
Affinity DataKi:  8.70nM ΔG°:  -45.4kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM50397913(CHEMBL2179516)
Affinity DataKi:  9.20nM ΔG°:  -45.3kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM141879(US8921410, Table 2 Compound 12)
Affinity DataKi:  9.5nM ΔG°:  -45.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM50397889(CHEMBL2179530)
Affinity DataKi:  9.70nM ΔG°:  -45.1kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM50397899(CHEMBL2179967)
Affinity DataKi:  9.90nM ΔG°:  -45.1kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM141886(US8921410, Table 2 Compound 24)
Affinity DataKi:  10nM ΔG°:  -45.0kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM141884(US8921410, Table 2 Compound 19)
Affinity DataKi:  12nM ΔG°:  -44.6kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM50397929(CHEMBL2179547)
Affinity DataKi:  12nM ΔG°:  -44.6kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM50397932(CHEMBL2179544)
Affinity DataKi:  13nM ΔG°:  -44.4kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM141856(US8921410, Table 1 Compound 20)
Affinity DataKi:  14nM ΔG°:  -44.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM141868(US8921410, Table 1 Compound 35)
Affinity DataKi:  14nM ΔG°:  -44.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM141872(US8921410, Table 1 Compound 41)
Affinity DataKi:  14nM ΔG°:  -44.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM50397935(CHEMBL2179541)
Affinity DataKi:  14nM ΔG°:  -44.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM50397913(CHEMBL2179516)
Affinity DataKi:  15nM ΔG°:  -44.1kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM50397933(CHEMBL2179543)
Affinity DataKi:  15nM ΔG°:  -44.1kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM50397893(CHEMBL2179526)
Affinity DataKi:  16nM ΔG°:  -43.9kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM50397928(CHEMBL2179548)
Affinity DataKi:  17nM ΔG°:  -43.8kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM141850(US8921410, Table 1 Compound 12)
Affinity DataKi:  17nM ΔG°:  -43.8kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM50397895(CHEMBL2179524)
Affinity DataKi:  18nM ΔG°:  -43.6kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM50397886(CHEMBL2179533)
Affinity DataKi:  18nM ΔG°:  -43.6kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM141875(US8921410, Table 2 Compound 8)
Affinity DataKi:  18nM ΔG°:  -43.6kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM141848(US8921410, Table 1 Compound 6)
Affinity DataKi:  19nM ΔG°:  -43.5kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM141848(US8921410, Table 1 Compound 6)
Affinity DataKi:  19nM ΔG°:  -43.5kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM141878(US8921410, Table 2 Compound 11)
Affinity DataKi:  20nM ΔG°:  -43.4kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM141867(US8921410, Table 1 Compound 33)
Affinity DataKi:  20nM ΔG°:  -43.4kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM50397900(CHEMBL2179966)
Affinity DataKi:  20nM ΔG°:  -43.4kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM141864(US8921410, Table 1 Compound 28)
Affinity DataKi:  20nM ΔG°:  -43.4kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM50397892(CHEMBL2179527)
Affinity DataKi:  21nM ΔG°:  -43.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM141866(US8921410, Table 1 Compound 30)
Affinity DataKi:  21nM ΔG°:  -43.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept

US Patent
LigandPNGBDBM50397889(CHEMBL2179530)
Affinity DataKi:  21nM ΔG°:  -43.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM141879(US8921410, Table 2 Compound 12)
Affinity DataKi:  21nM ΔG°:  -43.2kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM141864(US8921410, Table 1 Compound 28)
Affinity DataKi:  22nM ΔG°:  -43.1kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Targacept

US Patent
LigandPNGBDBM141883(US8921410, Table 2 Compound 18)
Affinity DataKi:  23nM ΔG°:  -43.0kJ/moleT: 2°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
In DepthDetails US Patent
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