Compile Data Set for Download or QSAR
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Found 7 Enz. Inhib. hit(s) with all data for entry = 6887
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Instytut Chemii Organicznej Polskiej Akademii Nauk

US Patent
LigandPNGBDBM156234(US9018255, L-3a)
Affinity DataIC50:  2.80E+3nMpH: 7.6Assay Description:The method of determining thioredoxin activity is based on the reduction of insulin by thioredoxin. Thioredoxin is reconstituted is by thioredoxin re...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Instytut Chemii Organicznej Polskiej Akademii Nauk

US Patent
LigandPNGBDBM156236(US9018255, 3b)
Affinity DataIC50:  2.90E+3nMpH: 7.6Assay Description:The method of determining thioredoxin activity is based on the reduction of insulin by thioredoxin. Thioredoxin is reconstituted is by thioredoxin re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Instytut Chemii Organicznej Polskiej Akademii Nauk

US Patent
LigandPNGBDBM156233(US9018255, 3a)
Affinity DataIC50:  3.20E+3nMpH: 7.6Assay Description:The method of determining thioredoxin activity is based on the reduction of insulin by thioredoxin. Thioredoxin is reconstituted is by thioredoxin re...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Instytut Chemii Organicznej Polskiej Akademii Nauk

US Patent
LigandPNGBDBM156235(US9018255, D-3a)
Affinity DataIC50:  3.50E+3nMpH: 7.6Assay Description:The method of determining thioredoxin activity is based on the reduction of insulin by thioredoxin. Thioredoxin is reconstituted is by thioredoxin re...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Instytut Chemii Organicznej Polskiej Akademii Nauk

US Patent
LigandPNGBDBM156238(US9018255, 8b)
Affinity DataIC50:  5.90E+3nMpH: 7.6Assay Description:The method of determining thioredoxin activity is based on the reduction of insulin by thioredoxin. Thioredoxin is reconstituted is by thioredoxin re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Instytut Chemii Organicznej Polskiej Akademii Nauk

US Patent
LigandPNGBDBM156237(US9018255, 8a)
Affinity DataIC50:  8.60E+3nMpH: 7.6Assay Description:The method of determining thioredoxin activity is based on the reduction of insulin by thioredoxin. Thioredoxin is reconstituted is by thioredoxin re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Instytut Chemii Organicznej Polskiej Akademii Nauk

US Patent
LigandPNGBDBM50426071(CHEMBL406050 | PX-12 | US9018255, PX-12 | med.2172...)
Affinity DataIC50:  1.54E+4nMpH: 7.6Assay Description:The method of determining thioredoxin activity is based on the reduction of insulin by thioredoxin. Thioredoxin is reconstituted is by thioredoxin re...More data for this Ligand-Target Pair
In DepthDetails US Patent