Compile Data Set for Download or QSAR
maximum 50k data
Found 15 Enz. Inhib. hit(s) with all data for entry = 7080
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM173197(US10137122, Compound 53 | US9096594, 54)
Affinity DataIC50:  12nMT: 2°CAssay Description:The GSK3beta primary screen was conducted in assay ready 1536 plates (Aurora 29847) that contain 2.5 mL/well of 10 mM compound. Human GSK3beta as a G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM173197(US10137122, Compound 53 | US9096594, 54)
Affinity DataIC50:  13nMT: 2°CAssay Description:The GSK3beta primary screen was conducted in assay ready 1536 plates (Aurora 29847) that contain 2.5 mL/well of 10 mM compound. Human GSK3beta as a G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM172196(US9090564, 10 | US9096594, 22)
Affinity DataIC50:  27nMT: 2°CAssay Description:The GSK3beta primary screen was conducted in assay ready 1536 plates (Aurora 29847) that contain 2.5 mL/well of 10 mM compound. Human GSK3beta as a G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM173196(4-(2-methoxyphenyl)-3,7,7-trimethyl-2,4,6,7,8,9-he...)
Affinity DataIC50:  61nMT: 2°CAssay Description:The GSK3beta primary screen was conducted in assay ready 1536 plates (Aurora 29847) that contain 2.5 mL/well of 10 mM compound. Human GSK3beta as a G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM173195(US10137122, Compound 3 | US9096594, 3)
Affinity DataIC50:  161nMT: 2°CAssay Description:The GSK3beta primary screen was conducted in assay ready 1536 plates (Aurora 29847) that contain 2.5 mL/well of 10 mM compound. Human GSK3beta as a G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM173195(US10137122, Compound 3 | US9096594, 3)
Affinity DataIC50:  232nMT: 2°CAssay Description:The GSK3beta primary screen was conducted in assay ready 1536 plates (Aurora 29847) that contain 2.5 mL/well of 10 mM compound. Human GSK3beta as a G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM173196(4-(2-methoxyphenyl)-3,7,7-trimethyl-2,4,6,7,8,9-he...)
Affinity DataIC50:  1.40E+3nMT: 2°CAssay Description:The GSK3beta primary screen was conducted in assay ready 1536 plates (Aurora 29847) that contain 2.5 mL/well of 10 mM compound. Human GSK3beta as a G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM172196(US9090564, 10 | US9096594, 22)
Affinity DataIC50:  1.50E+3nMT: 2°CAssay Description:The GSK3beta primary screen was conducted in assay ready 1536 plates (Aurora 29847) that contain 2.5 mL/well of 10 mM compound. Human GSK3beta as a G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM173197(US10137122, Compound 53 | US9096594, 54)
Affinity DataIC50:  1.80E+3nMT: 2°CAssay Description:The GSK3beta primary screen was conducted in assay ready 1536 plates (Aurora 29847) that contain 2.5 mL/well of 10 mM compound. Human GSK3beta as a G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM172196(US9090564, 10 | US9096594, 22)
Affinity DataIC50:  2.20E+3nMT: 2°CAssay Description:The GSK3beta primary screen was conducted in assay ready 1536 plates (Aurora 29847) that contain 2.5 mL/well of 10 mM compound. Human GSK3beta as a G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-A2 [177-432]/Cyclin-dependent kinase 2(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM172197(US9090564, 11 | US9096594, 54)
Affinity DataIC50:  3.90E+3nMT: 2°CAssay Description:The GSK3beta primary screen was conducted in assay ready 1536 plates (Aurora 29847) that contain 2.5 mL/well of 10 mM compound. Human GSK3beta as a G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM172197(US9090564, 11 | US9096594, 54)
Affinity DataIC50:  4.40E+3nMT: 2°CAssay Description:The GSK3beta primary screen was conducted in assay ready 1536 plates (Aurora 29847) that contain 2.5 mL/well of 10 mM compound. Human GSK3beta as a G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM173195(US10137122, Compound 3 | US9096594, 3)
Affinity DataIC50:  2.14E+4nMT: 2°CAssay Description:The GSK3beta primary screen was conducted in assay ready 1536 plates (Aurora 29847) that contain 2.5 mL/well of 10 mM compound. Human GSK3beta as a G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM173195(US10137122, Compound 3 | US9096594, 3)
Affinity DataIC50: >3.00E+4nMT: 2°CAssay Description:The GSK3beta primary screen was conducted in assay ready 1536 plates (Aurora 29847) that contain 2.5 mL/well of 10 mM compound. Human GSK3beta as a G...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM173195(US10137122, Compound 3 | US9096594, 3)
Affinity DataIC50: >3.00E+4nMT: 2°CAssay Description:The GSK3beta primary screen was conducted in assay ready 1536 plates (Aurora 29847) that contain 2.5 mL/well of 10 mM compound. Human GSK3beta as a G...More data for this Ligand-Target Pair
In DepthDetails US Patent