BindingDB logo
myBDB logout

USPatent US9187424

Compile Data Set for Download or QSAR

Found 434 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201322
PNG
(US9187424, 86)
Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccc(cc2)C(F)(F)F)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C31H25F9N2O3/c1-18-3-5-19(6-4-18)24-17-28(31(38,39)40,20-9-13-23(14-10-20)45-16-2-15-29(32,33)34)42-27(44)25(24)26(43)41-22-11-7-21(8-12-22)30(35,36)37/h3-14H,2,15-17H2,1H3,(H,41,43)(H,42,44)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 1n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201537
PNG
(US9187424, 304 | US9187424, 309)
Show SMILES Fc1cc(ccc1OCCCCCC(F)(F)F)C1(CC(=C(c2nn[nH]n2)C(=O)N1)c1ccc2ccccc2c1)C(F)(F)F
Show InChI InChI=1S/C29H24F7N5O2/c30-22-15-20(10-11-23(22)43-13-5-1-4-12-28(31,32)33)27(29(34,35)36)16-21(24(26(42)37-27)25-38-40-41-39-25)19-9-8-17-6-2-3-7-18(17)14-19/h2-3,6-11,14-15H,1,4-5,12-13,16H2,(H,37,42)(H,38,39,40,41)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 1n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201358
PNG
(US9187424, 122)
Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccc(O)cc2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C30H26F6N2O4/c1-18-3-5-19(6-4-18)24-17-28(30(34,35)36,20-7-13-23(14-8-20)42-16-2-15-29(31,32)33)38-27(41)25(24)26(40)37-21-9-11-22(39)12-10-21/h3-14,39H,2,15-17H2,1H3,(H,37,40)(H,38,41)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 1n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201507
PNG
(US9187424, 274)
Show SMILES FC(F)Oc1ccc(cc1)C1=C(c2nn[nH]n2)C(=O)NC(C1)(c1ccc(OCCCCCC(F)(F)F)cc1F)C(F)(F)F
Show InChI InChI=1S/C26H22F9N5O3/c27-19-12-16(42-11-3-1-2-10-25(30,31)32)8-9-18(19)24(26(33,34)35)13-17(14-4-6-15(7-5-14)43-23(28)29)20(22(41)36-24)21-37-39-40-38-21/h4-9,12,23H,1-3,10-11,13H2,(H,36,41)(H,37,38,39,40)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 1n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201319
PNG
(US9187424, 83)
Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccc(OC(F)(F)F)cc2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C31H25F9N2O4/c1-18-3-5-19(6-4-18)24-17-28(30(35,36)37,20-7-11-22(12-8-20)45-16-2-15-29(32,33)34)42-27(44)25(24)26(43)41-21-9-13-23(14-10-21)46-31(38,39)40/h3-14H,2,15-17H2,1H3,(H,41,43)(H,42,44)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 1n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201365
PNG
(US9187424, 130)
Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccno2)C(=O)NC(C1)(c1ccc(OCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C26H21F6N3O4/c1-15-2-4-16(5-3-15)19-14-24(26(30,31)32,17-6-8-18(9-7-17)38-13-11-25(27,28)29)35-23(37)21(19)22(36)34-20-10-12-33-39-20/h2-10,12H,11,13-14H2,1H3,(H,34,36)(H,35,37)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 1n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201529
PNG
(US9187424, 296)
Show SMILES COc1ccc(NC(=O)C2=C(CC(NC2=O)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c2ccc(C)cc2F)cc1
Show InChI InChI=1S/C31H27F7N2O4/c1-18-4-13-23(25(32)16-18)24-17-29(31(36,37)38,19-5-9-22(10-6-19)44-15-3-14-30(33,34)35)40-28(42)26(24)27(41)39-20-7-11-21(43-2)12-8-20/h4-13,16H,3,14-15,17H2,1-2H3,(H,39,41)(H,40,42)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201318
PNG
(US9187424, 82)
Show SMILES Cc1ccc(NC(=O)C2=C(CC(NC2=O)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c2ccc(C)cc2)cc1
Show InChI InChI=1S/C31H28F6N2O3/c1-19-4-8-21(9-5-19)25-18-29(31(35,36)37,22-10-14-24(15-11-22)42-17-3-16-30(32,33)34)39-28(41)26(25)27(40)38-23-12-6-20(2)7-13-23/h4-15H,3,16-18H2,1-2H3,(H,38,40)(H,39,41)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201320
PNG
(US9187424, 84)
Show SMILES COc1ccc(NC(=O)C2=C(CC(NC2=O)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c2ccc(C)cc2)cc1F
Show InChI InChI=1S/C31H27F7N2O4/c1-18-4-6-19(7-5-18)23-17-29(31(36,37)38,20-8-11-22(12-9-20)44-15-3-14-30(33,34)35)40-28(42)26(23)27(41)39-21-10-13-25(43-2)24(32)16-21/h4-13,16H,3,14-15,17H2,1-2H3,(H,39,41)(H,40,42)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201531
PNG
(US9187424, 298)
Show SMILES CCCCCCC#CC1(CC(=C(NC(=O)CNS(C)(=O)=O)C(=O)N1)c1ccc(C)cc1)C(F)(F)F
Show InChI InChI=1S/C24H30F3N3O4S/c1-4-5-6-7-8-9-14-23(24(25,26)27)15-19(18-12-10-17(2)11-13-18)21(22(32)30-23)29-20(31)16-28-35(3,33)34/h10-13,28H,4-8,15-16H2,1-3H3,(H,29,31)(H,30,32)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201444
PNG
(US9187424, 210)
Show SMILES FC(F)(F)CCCOc1ccc(cc1)C1(CC(=C(c2nn[nH]n2)C(=O)N1)c1ccc2CCCCc2c1)C(F)(F)F
Show InChI InChI=1S/C27H25F6N5O2/c28-26(29,30)12-3-13-40-20-10-8-19(9-11-20)25(27(31,32)33)15-21(22(24(39)34-25)23-35-37-38-36-23)18-7-6-16-4-1-2-5-17(16)14-18/h6-11,14H,1-5,12-13,15H2,(H,34,39)(H,35,36,37,38)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201509
PNG
(US9187424, 276)
Show SMILES Fc1cc(OCCCCCC(F)(F)F)ccc1C1(CC(=C(c2nn[nH]n2)C(=O)N1)c1ccc2ccccc2c1)C(F)(F)F
Show InChI InChI=1S/C29H24F7N5O2/c30-23-15-20(43-13-5-1-4-12-28(31,32)33)10-11-22(23)27(29(34,35)36)16-21(24(26(42)37-27)25-38-40-41-39-25)19-9-8-17-6-2-3-7-18(17)14-19/h2-3,6-11,14-15H,1,4-5,12-13,16H2,(H,37,42)(H,38,39,40,41)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201512
PNG
(US9187424, 279)
Show SMILES Cc1ccc(cc1)C1=C(NC(=O)CS(C)(=O)=O)C(=O)NC(C1)(c1ccc(OCc2ccccc2)cc1)C(F)(F)F
Show InChI InChI=1S/C29H27F3N2O5S/c1-19-8-10-21(11-9-19)24-16-28(29(30,31)32,34-27(36)26(24)33-25(35)18-40(2,37)38)22-12-14-23(15-13-22)39-17-20-6-4-3-5-7-20/h3-15H,16-18H2,1-2H3,(H,33,35)(H,34,36)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201401
PNG
(US9187424, 167)
Show SMILES FC(F)Oc1ccc(cc1)C1=C(NC(=O)c2ccno2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C27H21F8N3O5/c28-24(29)42-18-6-2-15(3-7-18)19-14-25(27(33,34)35,38-23(40)21(19)37-22(39)20-10-12-36-43-20)16-4-8-17(9-5-16)41-13-1-11-26(30,31)32/h2-10,12,24H,1,11,13-14H2,(H,37,39)(H,38,40)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201508
PNG
(US9187424, 275)
Show SMILES FC(F)Oc1ccc(cc1)C1=C(NC(=O)c2ccncc2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C29H23F8N3O4/c30-26(31)44-21-6-2-17(3-7-21)22-16-27(29(35,36)37,19-4-8-20(9-5-19)43-15-1-12-28(32,33)34)40-25(42)23(22)39-24(41)18-10-13-38-14-11-18/h2-11,13-14,26H,1,12,15-16H2,(H,39,41)(H,40,42)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201511
PNG
(US9187424, 278)
Show SMILES Cc1ccc(cc1)C1=C(c2nn[nH]n2)C(=O)NC(C1)(c1ccc(OCCCCC(F)(F)F)cc1F)C(F)(F)F
Show InChI InChI=1S/C25H22F7N5O2/c1-14-4-6-15(7-5-14)17-13-23(25(30,31)32,33-22(38)20(17)21-34-36-37-35-21)18-9-8-16(12-19(18)26)39-11-3-2-10-24(27,28)29/h4-9,12H,2-3,10-11,13H2,1H3,(H,33,38)(H,34,35,36,37)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201513
PNG
(US9187424, 280)
Show SMILES FC(F)Oc1ccc(cc1)C1=C(C(=O)Nc2cccnc2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C29H23F8N3O4/c30-26(31)44-21-8-4-17(5-9-21)22-15-27(29(35,36)37,18-6-10-20(11-7-18)43-14-2-12-28(32,33)34)40-25(42)23(22)24(41)39-19-3-1-13-38-16-19/h1,3-11,13,16,26H,2,12,14-15H2,(H,39,41)(H,40,42)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201239
PNG
(US9187424, 6-2)
Show SMILES COc1ccc(NC(=O)C2=C(C[C@](NC2=O)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c2ccc(C)cc2)cc1
Show InChI InChI=1S/C31H28F6N2O4/c1-19-4-6-20(7-5-19)25-18-29(31(35,36)37,21-8-12-24(13-9-21)43-17-3-16-30(32,33)34)39-28(41)26(25)27(40)38-22-10-14-23(42-2)15-11-22/h4-15H,3,16-18H2,1-2H3,(H,38,40)(H,39,41)/t29-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201413
PNG
(US9187424, 179)
Show SMILES Cc1ccc(cc1)C1=C(NC(=O)c2cc(Br)no2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C27H22BrF6N3O4/c1-15-3-5-16(6-4-15)19-14-25(27(32,33)34,17-7-9-18(10-8-17)40-12-2-11-26(29,30)31)36-24(39)22(19)35-23(38)20-13-21(28)37-41-20/h3-10,13H,2,11-12,14H2,1H3,(H,35,38)(H,36,39)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201317
PNG
(US9187424, 81 | US9187424, 91)
Show SMILES COc1ccc(C2=C(C#N)C(=O)NC(C2)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c(F)c1
Show InChI InChI=1S/C24H19F7N2O3/c1-35-16-7-8-17(20(25)11-16)18-12-22(24(29,30)31,33-21(34)19(18)13-32)14-3-5-15(6-4-14)36-10-2-9-23(26,27)28/h3-8,11H,2,9-10,12H2,1H3,(H,33,34)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201510
PNG
(US9187424, 277)
Show SMILES Fc1cc(OCCCC(F)(F)F)ccc1C1(CC(=C(c2nn[nH]n2)C(=O)N1)c1ccc(CC2CC2)cc1)C(F)(F)F
Show InChI InChI=1S/C27H24F7N5O2/c28-21-13-18(41-11-1-10-26(29,30)31)8-9-20(21)25(27(32,33)34)14-19(22(24(40)35-25)23-36-38-39-37-23)17-6-4-16(5-7-17)12-15-2-3-15/h4-9,13,15H,1-3,10-12,14H2,(H,35,40)(H,36,37,38,39)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201514
PNG
(US9187424, 281)
Show SMILES Cc1cc(NC(=O)C2=C(CC(NC2=O)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c2ccc(C)cc2)on1
Show InChI InChI=1S/C28H25F6N3O4/c1-16-4-6-18(7-5-16)21-15-26(28(32,33)34,19-8-10-20(11-9-19)40-13-3-12-27(29,30)31)36-25(39)23(21)24(38)35-22-14-17(2)37-41-22/h4-11,14H,3,12-13,15H2,1-2H3,(H,35,38)(H,36,39)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201544
PNG
(US9187424, 311)
Show SMILES CCCCCCCC#CC1(CC(=C(NC(=O)c2nnn[nH]2)C(=O)N1)c1ccc(C)cc1)C(F)(F)F
Show InChI InChI=1S/C24H27F3N6O2/c1-3-4-5-6-7-8-9-14-23(24(25,26)27)15-18(17-12-10-16(2)11-13-17)19(21(34)29-23)28-22(35)20-30-32-33-31-20/h10-13H,3-8,15H2,1-2H3,(H,28,35)(H,29,34)(H,30,31,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201484
PNG
(US9187424, 251)
Show SMILES CS(=O)(=O)CC(=O)NC1=C(CC(NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(OCC(F)F)cc1
Show InChI InChI=1S/C27H26F8N2O6S/c1-44(40,41)15-22(38)36-23-20(16-3-7-19(8-4-16)43-14-21(28)29)13-25(27(33,34)35,37-24(23)39)17-5-9-18(10-6-17)42-12-2-11-26(30,31)32/h3-10,21H,2,11-15H2,1H3,(H,36,38)(H,37,39)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201385
PNG
(US9187424, 150)
Show SMILES Cc1cc(on1)C(=O)NC1=C(c2ccc(C)cc2)C(F)(F)C(NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C28H23F8N3O4/c1-15-4-6-17(7-5-15)21-22(37-23(40)20-14-16(2)39-43-20)24(41)38-26(27(21,32)33,28(34,35)36)18-8-10-19(11-9-18)42-13-3-12-25(29,30)31/h4-11,14H,3,12-13H2,1-2H3,(H,37,40)(H,38,41)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201515
PNG
(US9187424, 282)
Show SMILES CCOP(=O)(CC(=O)NC1=C(CC(NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(C)cc1)OCC
Show InChI InChI=1S/C29H33F6N2O6P/c1-4-42-44(40,43-5-2)18-24(38)36-25-23(20-9-7-19(3)8-10-20)17-27(29(33,34)35,37-26(25)39)21-11-13-22(14-12-21)41-16-6-15-28(30,31)32/h7-14H,4-6,15-18H2,1-3H3,(H,36,38)(H,37,39)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201269
PNG
(US9187424, 269 | US9187424, 33 | US9187424, 53 | U...)
Show SMILES Cc1ccc(cc1)C1=C(C#N)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C24H20F6N2O2/c1-15-3-5-16(6-4-15)19-13-22(24(28,29)30,32-21(33)20(19)14-31)17-7-9-18(10-8-17)34-12-2-11-23(25,26)27/h3-10H,2,11-13H2,1H3,(H,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201540
PNG
(US9187424, 307)
Show SMILES CCCCCCC#Cc1ccc(cc1F)C1(CC(=C(c2nn[nH]n2)C(=O)N1)c1ccc(OC(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C28H25F6N5O2/c1-2-3-4-5-6-7-8-18-9-12-19(15-22(18)29)27(28(32,33)34)16-21(17-10-13-20(14-11-17)41-26(30)31)23(25(40)35-27)24-36-38-39-37-24/h9-15,26H,2-6,16H2,1H3,(H,35,40)(H,36,37,38,39)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201301
PNG
(US9187424, 65 | US9187424, 77)
Show SMILES COc1ccc(cc1)C1=C(C#N)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C24H20F6N2O3/c1-34-17-7-3-15(4-8-17)19-13-22(24(28,29)30,32-21(33)20(19)14-31)16-5-9-18(10-6-16)35-12-2-11-23(25,26)27/h3-10H,2,11-13H2,1H3,(H,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201406
PNG
(US9187424, 172)
Show SMILES CCCCOc1ccc(cc1)C1(CC(=C(NC(=O)c2ccno2)C(=O)N1)c1ccc(OC)cc1)C(F)(F)F
Show InChI InChI=1S/C27H26F3N3O5/c1-3-4-15-37-20-11-7-18(8-12-20)26(27(28,29)30)16-21(17-5-9-19(36-2)10-6-17)23(25(35)33-26)32-24(34)22-13-14-31-38-22/h5-14H,3-4,15-16H2,1-2H3,(H,32,34)(H,33,35)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201410
PNG
(US9187424, 176)
Show SMILES COc1ccc(cc1)C1=C(NC(=O)c2cc(C)no2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C28H25F6N3O5/c1-16-14-22(42-37-16)24(38)35-23-21(17-4-8-19(40-2)9-5-17)15-26(28(32,33)34,36-25(23)39)18-6-10-20(11-7-18)41-13-3-12-27(29,30)31/h4-11,14H,3,12-13,15H2,1-2H3,(H,35,38)(H,36,39)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201516
PNG
(US9187424, 283)
Show SMILES CCOc1ccc(cc1)C1=C(c2nn[nH]n2)C(=O)NC(C1)(c1ccc(OCCCCCC(F)(F)F)cc1F)C(F)(F)F
Show InChI InChI=1S/C27H26F7N5O3/c1-2-41-17-8-6-16(7-9-17)19-15-25(27(32,33)34,35-24(40)22(19)23-36-38-39-37-23)20-11-10-18(14-21(20)28)42-13-5-3-4-12-26(29,30)31/h6-11,14H,2-5,12-13,15H2,1H3,(H,35,40)(H,36,37,38,39)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201539
PNG
(US9187424, 306)
Show SMILES Fc1cc(ccc1OCCCCCC(F)(F)F)C1(CC(=C(c2nn[nH]n2)C(=O)N1)c1ccc(CC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C27H23F10N5O2/c28-19-12-17(8-9-20(19)44-11-3-1-2-10-25(29,30)31)24(27(35,36)37)14-18(21(23(43)38-24)22-39-41-42-40-22)16-6-4-15(5-7-16)13-26(32,33)34/h4-9,12H,1-3,10-11,13-14H2,(H,38,43)(H,39,40,41,42)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201295
PNG
(US9187424, 59)
Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccccc2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C30H26F6N2O3/c1-19-8-10-20(11-9-19)24-18-28(30(34,35)36,21-12-14-23(15-13-21)41-17-5-16-29(31,32)33)38-27(40)25(24)26(39)37-22-6-3-2-4-7-22/h2-4,6-15H,5,16-18H2,1H3,(H,37,39)(H,38,40)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201377
PNG
(US9187424, 143)
Show SMILES COc1ccc(cc1)C1=C(C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)n1cnnn1
Show InChI InChI=1S/C24H21F6N5O3/c1-37-17-7-3-15(4-8-17)19-13-22(24(28,29)30,32-21(36)20(19)35-14-31-33-34-35)16-5-9-18(10-6-16)38-12-2-11-23(25,26)27/h3-10,14H,2,11-13H2,1H3,(H,32,36)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201330
PNG
(US9187424, 94)
Show SMILES Cc1ccc(cc1)C1=C(C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C30H24F9NO3/c1-18-3-5-19(6-4-18)24-17-27(29(34,35)36,21-9-13-22(14-10-21)42-16-2-15-28(31,32)33)40-26(41)25(24)20-7-11-23(12-8-20)43-30(37,38)39/h3-14H,2,15-17H2,1H3,(H,40,41)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201543
PNG
(US9187424, 310)
Show SMILES Cc1ccc(cc1)C1=C(NC(=O)c2nnn[nH]2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C25H22F6N6O3/c1-14-3-5-15(6-4-14)18-13-23(25(29,30)31,33-21(38)19(18)32-22(39)20-34-36-37-35-20)16-7-9-17(10-8-16)40-12-2-11-24(26,27)28/h3-10H,2,11-13H2,1H3,(H,32,39)(H,33,38)(H,34,35,36,37)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201421
PNG
(US9187424, 187)
Show SMILES COc1cc(on1)C(=O)NC1=C(CC(NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(C)cc1
Show InChI InChI=1S/C28H25F6N3O5/c1-16-4-6-17(7-5-16)20-15-26(28(32,33)34,18-8-10-19(11-9-18)41-13-3-12-27(29,30)31)36-25(39)23(20)35-24(38)21-14-22(40-2)37-42-21/h4-11,14H,3,12-13,15H2,1-2H3,(H,35,38)(H,36,39)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201517
PNG
(US9187424, 284)
Show SMILES Fc1cc(OCCCCCC(F)(F)F)ccc1C1(CC(=C(c2nn[nH]n2)C(=O)N1)c1ccc(CC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C27H23F10N5O2/c28-20-12-17(44-11-3-1-2-10-25(29,30)31)8-9-19(20)24(27(35,36)37)14-18(21(23(43)38-24)22-39-41-42-40-22)16-6-4-15(5-7-16)13-26(32,33)34/h4-9,12H,1-3,10-11,13-14H2,(H,38,43)(H,39,40,41,42)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201314
PNG
(US9187424, 144 | US9187424, 78)
Show SMILES FC(F)Oc1ccc(cc1)C1=C(C#N)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C24H18F8N2O3/c25-21(26)37-17-6-2-14(3-7-17)18-12-22(24(30,31)32,34-20(35)19(18)13-33)15-4-8-16(9-5-15)36-11-1-10-23(27,28)29/h2-9,21H,1,10-12H2,(H,34,35)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201317
PNG
(US9187424, 81 | US9187424, 91)
Show SMILES COc1ccc(C2=C(C#N)C(=O)NC(C2)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c(F)c1
Show InChI InChI=1S/C24H19F7N2O3/c1-35-16-7-8-17(20(25)11-16)18-12-22(24(29,30)31,33-21(34)19(18)13-32)14-3-5-15(6-4-14)36-10-2-9-23(26,27)28/h3-8,11H,2,9-10,12H2,1H3,(H,33,34)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201354
PNG
(US9187424, 118)
Show SMILES Cc1ccc(cc1)C1=C(c2nn[nH]n2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)C(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C25H21F8N5O2/c1-14-3-5-15(6-4-14)18-13-22(24(28,29)30,34-21(39)19(18)20-35-37-38-36-20)16-7-9-17(10-8-16)40-12-2-11-23(26,27)25(31,32)33/h3-10H,2,11-13H2,1H3,(H,34,39)(H,35,36,37,38)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201519
PNG
(US9187424, 286)
Show SMILES Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(C2)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c(F)c1
Show InChI InChI=1S/C24H20F7N5O2/c1-13-3-8-16(18(25)11-13)17-12-22(24(29,30)31,32-21(37)19(17)20-33-35-36-34-20)14-4-6-15(7-5-14)38-10-2-9-23(26,27)28/h3-8,11H,2,9-10,12H2,1H3,(H,32,37)(H,33,34,35,36)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201352
PNG
(US9187424, 116 | US9187424, 183 | US9187424, 270)
Show SMILES Cc1ccc(cc1)C1=C(c2nn[nH]n2)C(=O)NC(C1)(c1ccc(OCCCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C26H25F6N5O2/c1-16-5-7-17(8-6-16)20-15-24(26(30,31)32,33-23(38)21(20)22-34-36-37-35-22)18-9-11-19(12-10-18)39-14-4-2-3-13-25(27,28)29/h5-12H,2-4,13-15H2,1H3,(H,33,38)(H,34,35,36,37)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201518
PNG
(US9187424, 285)
Show SMILES Cc1ccc(cc1)C1=C(c2nn[nH]n2)C(=O)NC(C1)(c1ccc(OCCC2CC2)cc1)C(F)(F)F
Show InChI InChI=1S/C25H24F3N5O2/c1-15-2-6-17(7-3-15)20-14-24(25(26,27)28,29-23(34)21(20)22-30-32-33-31-22)18-8-10-19(11-9-18)35-13-12-16-4-5-16/h2-3,6-11,16H,4-5,12-14H2,1H3,(H,29,34)(H,30,31,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201546
PNG
(US9187424, 313)
Show SMILES CCCCCCCC#CC1(CC(=C(NC(=O)CS(C)(=O)=O)C(=O)N1)c1ccc(OC(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C25H29F5N2O5S/c1-3-4-5-6-7-8-9-14-24(25(28,29)30)15-19(17-10-12-18(13-11-17)37-23(26)27)21(22(34)32-24)31-20(33)16-38(2,35)36/h10-13,23H,3-8,15-16H2,1-2H3,(H,31,33)(H,32,34)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201232
PNG
(US9187424, 2 | US9187424, 2-1)
Show SMILES Cc1ccc(cc1)C1=C(c2nnn[nH]2)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C24H21F6N5O2/c1-14-3-5-15(6-4-14)18-13-22(24(28,29)30,31-21(36)19(18)20-32-34-35-33-20)16-7-9-17(10-8-16)37-12-2-11-23(25,26)27/h3-10H,2,11-13H2,1H3,(H,31,36)(H,32,33,34,35)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 5n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201316
PNG
(US9187424, 145 | US9187424, 80)
Show SMILES CCOc1ccc(cc1)C1=C(C#N)C(=O)NC(C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F
Show InChI InChI=1S/C25H22F6N2O3/c1-2-35-18-8-4-16(5-9-18)20-14-23(25(29,30)31,33-22(34)21(20)15-32)17-6-10-19(11-7-17)36-13-3-12-24(26,27)28/h4-11H,2-3,12-14H2,1H3,(H,33,34)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 5n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201324
PNG
(US9187424, 88)
Show SMILES COc1ccc(NC(=O)C2=C(CC(NC2=O)(c2ccc(OCC(F)(F)F)cc2)C(F)(F)F)c2ccc(C)cc2)cc1
Show InChI InChI=1S/C29H24F6N2O4/c1-17-3-5-18(6-4-17)23-15-27(29(33,34)35,19-7-11-22(12-8-19)41-16-28(30,31)32)37-26(39)24(23)25(38)36-20-9-13-21(40-2)14-10-20/h3-14H,15-16H2,1-2H3,(H,36,38)(H,37,39)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 5n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Monoacylglycerol acyltransferase type 2 (h-MGAT2)


(Homo sapiens (Human))
BDBM201346
PNG
(US9187424, 110)
Show SMILES COc1ccc(NC(=O)C2=C(CC(NC2=O)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c2ccc(C)cc2)cn1
Show InChI InChI=1S/C30H27F6N3O4/c1-18-4-6-19(7-5-18)23-16-28(30(34,35)36,20-8-11-22(12-9-20)43-15-3-14-29(31,32)33)39-27(41)25(23)26(40)38-21-10-13-24(42-2)37-17-21/h4-13,17H,3,14-16H2,1-2H3,(H,38,40)(H,39,41)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 5n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...


US Patent US9187424 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9VFG
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 434 total )  |  Next  |  Last  >>
* indicates data uncertainty>20%