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Found 43 Enz. Inhib. hit(s) with all data for entry = 8181
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM47165(US8957103, C1 | US9364459, I)
Affinity DataIC50:  2nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235821(US9364459, H)
Affinity DataIC50:  3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM50399331(CHEMBL2180882 | US9364459, C)
Affinity DataIC50: <10nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM50399333(CHEMBL2177142 | US9364459, D)
Affinity DataIC50:  23nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM50399334(CHEMBL2180878 | US9364459, B)
Affinity DataIC50:  37nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM50399331(CHEMBL2180882 | US9364459, C)
Affinity DataIC50:  48nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM50399333(CHEMBL2177142 | US9364459, D)
Affinity DataIC50:  50nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM47167(CHEMBL201511 | US8957103, Z1 | US9364459, A)
Affinity DataIC50:  90nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235820(US9364459, G)
Affinity DataIC50:  129nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM50399334(CHEMBL2180878 | US9364459, B)
Affinity DataIC50:  132nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235821(US9364459, H)
Affinity DataIC50:  153nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM47167(CHEMBL201511 | US8957103, Z1 | US9364459, A)
Affinity DataIC50:  166nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM50309549(3-(5-Fluoro-1H-indol-3-yl)-4-(3,4,5-trimethoxyphen...)
Affinity DataIC50:  182nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235819(US9364459, F)
Affinity DataIC50:  195nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM50399332(CHEMBL2180881 | US9364459, E)
Affinity DataIC50:  215nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235819(US9364459, F)
Affinity DataIC50:  227nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM50399332(CHEMBL2180881 | US9364459, E)
Affinity DataIC50:  373nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235821(US9364459, H)
Affinity DataIC50:  554nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM47165(US8957103, C1 | US9364459, I)
Affinity DataIC50:  556nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235825(US9364459, M)
Affinity DataIC50:  657nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM47165(US8957103, C1 | US9364459, I)
Affinity DataIC50:  920nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235820(US9364459, G)
Affinity DataIC50: >1.00E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235823(US9364459, K)
Affinity DataIC50: >1.00E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235824(US9364459, L)
Affinity DataIC50: >1.00E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235822(US9364459, J)
Affinity DataIC50: >1.00E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM47167(CHEMBL201511 | US8957103, Z1 | US9364459, A)
Affinity DataIC50:  1.10E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235824(US9364459, L)
Affinity DataIC50:  1.21E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235824(US9364459, L)
Affinity DataIC50:  1.24E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235822(US9364459, J)
Affinity DataIC50:  1.30E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235820(US9364459, G)
Affinity DataIC50:  1.50E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM50399332(CHEMBL2180881 | US9364459, E)
Affinity DataIC50:  1.52E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235823(US9364459, K)
Affinity DataIC50:  1.53E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235819(US9364459, F)
Affinity DataIC50:  1.89E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM50399331(CHEMBL2180882 | US9364459, C)
Affinity DataIC50:  1.90E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235826(US9364459, N)
Affinity DataIC50:  2.83E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235826(US9364459, N)
Affinity DataIC50:  3.24E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235822(US9364459, J)
Affinity DataIC50:  3.58E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM50399333(CHEMBL2177142 | US9364459, D)
Affinity DataIC50:  6.27E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235825(US9364459, M)
Affinity DataIC50:  9.20E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM50399334(CHEMBL2180878 | US9364459, B)
Affinity DataIC50: >1.00E+4nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235826(US9364459, N)
Affinity DataIC50: >1.00E+4nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235825(US9364459, M)
Affinity DataIC50: >1.00E+4nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM235823(US9364459, K)
Affinity DataIC50: >1.00E+4nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent