Compile Data Set for Download or QSAR
maximum 50k data
Found 470 Enz. Inhib. hit(s) with all data for entry = 1858
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344702(US9783527, Example 5 | isobutyl 3-[1-(2-fluorophen...)
Affinity DataIC50:  57.2nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.8 (Essen, Ann Arbor, Mich.) were quickly thawed and pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344702(US9783527, Example 5 | isobutyl 3-[1-(2-fluorophen...)
Affinity DataIC50:  166nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344943(1-[1-(2-fluorophenyl)-1H- | 1-[1-(2-fluorophenyl)-...)
Affinity DataIC50:  207nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344701(US9783527, Example 4 | isopropyl 3-[1-(2-fluorophe...)
Affinity DataIC50:  223nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344701(US9783527, Example 4 | isopropyl 3-[1-(2-fluorophe...)
Affinity DataIC50:  230nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.8 (Essen, Ann Arbor, Mich.) were quickly thawed and pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344740(1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-[(6-methy...)
Affinity DataIC50:  265nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344869(1-[1-(2-fluorophenyl)-1H- | 1-[1-(2-fluorophenyl)-...)
Affinity DataIC50:  285nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344829(US9783527, Example 131 | cyclohexyl 3-[1-(2- | cyc...)
Affinity DataIC50:  286nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344737(1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-(1,3-thia...)
Affinity DataIC50:  301nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344719(1-{2-[(2S)-2-ethylpyrrolidin-1-yl]-2-oxoethyl}-3-[...)
Affinity DataIC50:  314nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344710(1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-(pyridin-...)
Affinity DataIC50:  321nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.8 (Essen, Ann Arbor, Mich.) were quickly thawed and pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344722(1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-[(4-methy...)
Affinity DataIC50:  338nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344970(1-[(1R,2R)-2- | 1-[(1R,2R)-2-(benzyloxy)cyclohexyl...)
Affinity DataIC50:  338nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344824(1-[1-(2-fluorophenyl)-1H- | 1-[1-(2-fluorophenyl)-...)
Affinity DataIC50:  343nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM345006(1-[1-(2-fluorophenyl)-1H- | 1-[1-(2-fluorophenyl)-...)
Affinity DataIC50:  345nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.8 (Essen, Ann Arbor, Mich.) were quickly thawed and pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344821(1-[1-(2-fluorophenyl)-1H- | 1-[1-(2-fluorophenyl)-...)
Affinity DataIC50:  346nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344786(1-{2-[(3S)-3- | 1-{2-[(3S)-3-fluoropyrrolidin-1-yl...)
Affinity DataIC50:  351nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344937(1-[(2,5-dimethyl-1,3- | 1-[(2,5-dimethyl-1,3-thiaz...)
Affinity DataIC50:  352nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344708(1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-{2-[(3S)-...)
Affinity DataIC50:  375nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344724(1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-(1,3-oxaz...)
Affinity DataIC50:  382nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344735(1-[1-(2,4-difluorophenyl)-1H-indazol-4-yl]-3-(1,3-...)
Affinity DataIC50:  392nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344997(1-[1-(2-fluorophenyl)-1H- | 1-[1-(2-fluorophenyl)-...)
Affinity DataIC50:  398nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.8 (Essen, Ann Arbor, Mich.) were quickly thawed and pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344827(1-[1-(2-fluorophenyl)-1H- | 1-[1-(2-fluorophenyl)-...)
Affinity DataIC50:  403nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344711(N-cyclopropyl-2-{3-[1-(2-fluorophenyl)-1H-indazol-...)
Affinity DataIC50:  406nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.8 (Essen, Ann Arbor, Mich.) were quickly thawed and pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344732(1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-(1,3-thia...)
Affinity DataIC50:  420nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344864(1-(2-cyclobutyl-1-hydroxy- | 1-(2-cyclobutyl-1-hyd...)
Affinity DataIC50:  435nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344726(1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-(pyrimidi...)
Affinity DataIC50:  457nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344797(1-[1-(2-fluorophenyl)-1H- | 1-[1-(2-fluorophenyl)-...)
Affinity DataIC50:  482nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344709(1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-{2-[(3S)-...)
Affinity DataIC50:  483nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344706(1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-(4-methyl...)
Affinity DataIC50:  491nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344961(1-[1-(2-fluorophenyl)-1H- | 1-[1-(2-fluorophenyl)-...)
Affinity DataIC50:  494nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344723(1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-{2-[(1R,4...)
Affinity DataIC50:  499nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM345033(N-[(1R,2R)-2- | N-[(1R,2R)-2-(benzyloxy)cyclopenty...)
Affinity DataIC50:  501nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.8 (Essen, Ann Arbor, Mich.) were quickly thawed and pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344724(1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-(1,3-oxaz...)
Affinity DataIC50:  517nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.8 (Essen, Ann Arbor, Mich.) were quickly thawed and pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344978(1-[1-(2-fluorophenyl)-1H- | 1-[1-(2-fluorophenyl)-...)
Affinity DataIC50:  518nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM345005(1-{2-[(3S)-3- | 1-{2-[(3S)-3-fluoropyrrolidin-1-yl...)
Affinity DataIC50:  520nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344831(1-[1-(2-fluorophenyl)-1H- | 1-[1-(2-fluorophenyl)-...)
Affinity DataIC50:  525nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM345022(N-cyclohexyl-2-{3-[1-(2- | N-cyclohexyl-2-{3-[1-(2...)
Affinity DataIC50:  526nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.8 (Essen, Ann Arbor, Mich.) were quickly thawed and pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344747(1-[(5-cyclopropyl-1,3,4-oxadiazol-2-yl)methyl]-3-[...)
Affinity DataIC50:  538nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.8 (Essen, Ann Arbor, Mich.) were quickly thawed and pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344725(1-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]-3-[1-(2-f...)
Affinity DataIC50:  546nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344716(1-{2-[(2R,4S)-2-(2,5-difluorophenyl)-4-fluoropyrro...)
Affinity DataIC50:  578nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344936(1-[(4,5-dimethyl-1,3- | 1-[(4,5-dimethyl-1,3-oxazo...)
Affinity DataIC50:  586nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344892(1-(cyclopropylmethyl)-3-[1- | 1-(cyclopropylmethyl...)
Affinity DataIC50:  613nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344712(1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-{[4-(trif...)
Affinity DataIC50:  618nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344731(1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-(5-methyl...)
Affinity DataIC50:  624nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344713(1-[1-(2-fluorophenyl)-1H-indazol-4-yl]-3-{2-[(2S)-...)
Affinity DataIC50:  625nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344804(1-[1-(2-fluorophenyl)-1H- | 1-[1-(2-fluorophenyl)-...)
Affinity DataIC50:  635nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344862(1-(2-cyclobutyl-2- | 1-(2-cyclobutyl-2-oxoethyl)-3...)
Affinity DataIC50:  635nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 10 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM345038(N-(3,3-difluorocyclohexyl)- | N-(3,3-difluorocyclo...)
Affinity DataIC50:  637nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.8 (Essen, Ann Arbor, Mich.) were quickly thawed and pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM344734(1-[1-(2,4-difluorophenyl)-1H-indazol-4-yl]-3-(1,3-...)
Affinity DataIC50:  643nMAssay Description:Two days prior to the experiment, frozen HEK293 cells stably expressing recombinant human Nav1.7 were quickly thawed and plated at 25,000 cells/well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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