Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with all data for entry = 2900
TargetBile acid receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM384545(2-(7-((5-cyclopropyl-3-(2,6- dichlorophenyl)isoxaz...)
Affinity DataIC50:  19nMAssay Description:The human FXRalpha LBD was expressed in E. coli strain BL21(DE3) as an N-terminally GST tagged fusion protein. The DNA encoding the FXR ligand bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM384546(2-(7-((5-cyclopropyl-3-(2,6- dichlorophenyl)isoxaz...)
Affinity DataIC50:  30nMAssay Description:The human FXRalpha LBD was expressed in E. coli strain BL21(DE3) as an N-terminally GST tagged fusion protein. The DNA encoding the FXR ligand bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent