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PubChem AID 434954

Compile Data Set for Download or QSAR

Found 2198 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68356
PNG
(8-Bromo-7-(2-chloro-benzyl)-3-methyl-3,7-dihydro-p...)
Show SMILES Cn1c2nc(Br)n(Cc3ccccc3Cl)c2c(=O)[nH]c1=O
Show InChI InChI=1S/C13H10BrClN4O2/c1-18-10-9(11(20)17-13(18)21)19(12(14)16-10)6-7-4-2-3-5-8(7)15/h2-5H,6H2,1H3,(H,17,20,21)
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68358
PNG
(7-Ethyl-5-thiophen-2-yl-1,3-dihydro-thieno[2,3-e][...)
Show SMILES CCc1cc2c(NC(=O)CN=C2c2cccs2)s1
Show InChI InChI=1S/C13H12N2OS2/c1-2-8-6-9-12(10-4-3-5-17-10)14-7-11(16)15-13(9)18-8/h3-6H,2,7H2,1H3,(H,15,16)
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n/an/an/an/a 3.27E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68359
PNG
(MLS000032454 | N-(4-Acetylamino-phenyl)-2-(5-cyclo...)
Show SMILES CCn1c(SCC(=O)Nc2ccc(NC(C)=O)cc2)nnc1C1CC1
Show InChI InChI=1S/C17H21N5O2S/c1-3-22-16(12-4-5-12)20-21-17(22)25-10-15(24)19-14-8-6-13(7-9-14)18-11(2)23/h6-9,12H,3-5,10H2,1-2H3,(H,18,23)(H,19,24)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68361
PNG
(1-(2-pyridinyl)-3-pyridin-4-ylurea | 1-(2-pyridyl)...)
Show SMILES O=C(Nc1ccncc1)Nc1ccccn1
Show InChI InChI=1S/C11H10N4O/c16-11(14-9-4-7-12-8-5-9)15-10-3-1-2-6-13-10/h1-8H,(H2,12,13,14,15,16)
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n/an/an/an/a 4.96E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM38798
PNG
(3-piperidin-1-ylpropyl 4-hydroxybenzoate | 3-piper...)
Show SMILES Oc1ccc(cc1)C(=O)OCCCN1CCCCC1
Show InChI InChI=1S/C15H21NO3/c17-14-7-5-13(6-8-14)15(18)19-12-4-11-16-9-2-1-3-10-16/h5-8,17H,1-4,9-12H2
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68375
PNG
(4-[4-(3,4-Dimethoxy-phenyl)-thiazol-2-yl]-morpholi...)
Show SMILES COc1ccc(cc1OC)-c1csc(n1)N1CCOCC1
Show InChI InChI=1S/C15H18N2O3S/c1-18-13-4-3-11(9-14(13)19-2)12-10-21-15(16-12)17-5-7-20-8-6-17/h3-4,9-10H,5-8H2,1-2H3
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68378
PNG
(MLS000073940 | N-(3-Cyano-4,5-dimethyl-thiophen-2-...)
Show SMILES Cc1sc(NC(=O)CSc2nnc(COc3cccc(C)c3)n2C)c(C#N)c1C
Show InChI InChI=1S/C20H21N5O2S2/c1-12-6-5-7-15(8-12)27-10-17-23-24-20(25(17)4)28-11-18(26)22-19-16(9-21)13(2)14(3)29-19/h5-8H,10-11H2,1-4H3,(H,22,26)
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68379
PNG
((1-Benzenesulfonyl-piperidin-3-yl)-(4-pyrimidin-2-...)
Show SMILES O=C(C1CCCN(C1)S(=O)(=O)c1ccccc1)N1CCN(CC1)c1ncccn1
Show InChI InChI=1S/C20H25N5O3S/c26-19(23-12-14-24(15-13-23)20-21-9-5-10-22-20)17-6-4-11-25(16-17)29(27,28)18-7-2-1-3-8-18/h1-3,5,7-10,17H,4,6,11-16H2
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68384
PNG
(2-(1,3-benzodioxol-5-yl)-5-(4-pyridylmethylthio)-1...)
Show SMILES C(Sc1nnc(o1)-c1ccc2OCOc2c1)c1ccncc1
Show InChI InChI=1S/C15H11N3O3S/c1-2-12-13(20-9-19-12)7-11(1)14-17-18-15(21-14)22-8-10-3-5-16-6-4-10/h1-7H,8-9H2
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n/an/an/an/a 1.71E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68386
PNG
(2,2-Dimethyl-6-(morpholine-4-carbonyl)-4-(2-morpho...)
Show SMILES CC1(C)Oc2ccc(cc2N(CC(=O)N2CCOCC2)C1=O)C(=O)N1CCOCC1
Show InChI InChI=1S/C21H27N3O6/c1-21(2)20(27)24(14-18(25)22-5-9-28-10-6-22)16-13-15(3-4-17(16)30-21)19(26)23-7-11-29-12-8-23/h3-4,13H,5-12,14H2,1-2H3
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68388
PNG
(2-[[5-(3-cyanophenyl)-1,3,4-oxadiazol-2-yl]sulfany...)
Show SMILES N#Cc1cccc(c1)-c1nnc(SCc2ccccc2C#N)o1
Show InChI InChI=1S/C17H10N4OS/c18-9-12-4-3-7-13(8-12)16-20-21-17(22-16)23-11-15-6-2-1-5-14(15)10-19/h1-8H,11H2
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68389
PNG
(2-(2-thienyl)-2,3,5,6,7,8-hexahydro-1H-benzothioph...)
Show SMILES O=C1NC(Nc2sc3CCCCc3c12)c1cccs1
Show InChI InChI=1S/C14H14N2OS2/c17-13-11-8-4-1-2-5-9(8)19-14(11)16-12(15-13)10-6-3-7-18-10/h3,6-7,12,16H,1-2,4-5H2,(H,15,17)
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68390
PNG
(4-(3-Ethoxy-4-hydroxy-phenyl)-2,7,7-trimethyl-3-(p...)
Show SMILES CCOc1cc(ccc1O)C1C2C(=O)CC(C)(C)CC2=NC(C)=C1C(=O)N1CCCCC1
Show InChI InChI=1S/C26H34N2O4/c1-5-32-21-13-17(9-10-19(21)29)23-22(25(31)28-11-7-6-8-12-28)16(2)27-18-14-26(3,4)15-20(30)24(18)23/h9-10,13,23-24,29H,5-8,11-12,14-15H2,1-4H3
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM14487
PNG
((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...)
Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68399
PNG
(7-ethyl-1-(4-morpholinyl)-3-(1-piperidinyl)-6,8-di...)
Show SMILES CCN1CCc2c(C1)c(nc(N1CCCCC1)c2C#N)N1CCOCC1
Show InChI InChI=1S/C20H29N5O/c1-2-23-9-6-16-17(14-21)19(24-7-4-3-5-8-24)22-20(18(16)15-23)25-10-12-26-13-11-25/h2-13,15H2,1H3
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n/an/an/an/a 1.61E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM36899
PNG
(1-cyano-2-[2-(2,4-dichlorophenyl)-2-keto-ethyl]-3-...)
Show SMILES CNC(SCC(=O)c1ccc(Cl)cc1Cl)=NC#N
Show InChI InChI=1S/C11H9Cl2N3OS/c1-15-11(16-6-14)18-5-10(17)8-3-2-7(12)4-9(8)13/h2-4H,5H2,1H3,(H,15,16)
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n/an/an/an/a 3.19E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68407
PNG
(2-[3-(4-benzylpiperazino)quinoxalin-2-yl]-2-cyano-...)
Show SMILES COCCOC(=O)C(C#N)c1nc2ccccc2nc1N1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C25H27N5O3/c1-32-15-16-33-25(31)20(17-26)23-24(28-22-10-6-5-9-21(22)27-23)30-13-11-29(12-14-30)18-19-7-3-2-4-8-19/h2-10,20H,11-16,18H2,1H3
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68409
PNG
(2-(3-cyano-6-pyridin-3-yl-pyridin-2-yl)sulfanyl-N-...)
Show SMILES Cc1cc(NC(=O)CSc2nc(ccc2C#N)-c2cccnc2)no1
Show InChI InChI=1S/C17H13N5O2S/c1-11-7-15(22-24-11)21-16(23)10-25-17-12(8-18)4-5-14(20-17)13-3-2-6-19-9-13/h2-7,9H,10H2,1H3,(H,21,22,23)
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68416
PNG
((5E)-1-(4-fluorobenzyl)-5-[(2-piperidinoethylamino...)
Show SMILES Fc1ccc(CN2C(=O)NC(=O)C(=CNCCN3CCCCC3)C2=O)cc1
Show InChI InChI=1S/C19H23FN4O3/c20-15-6-4-14(5-7-15)13-24-18(26)16(17(25)22-19(24)27)12-21-8-11-23-9-2-1-3-10-23/h4-7,12,21H,1-3,8-11,13H2,(H,22,25,27)
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM48541
PNG
(4-(3-ethoxy-4-hydroxy-phenyl)-3-methyl-5-(p-tolyl)...)
Show SMILES CCOc1cc(ccc1O)C1N(C(=O)c2n[nH]c(C)c12)c1ccc(C)cc1
Show InChI InChI=1S/C21H21N3O3/c1-4-27-17-11-14(7-10-16(17)25)20-18-13(3)22-23-19(18)21(26)24(20)15-8-5-12(2)6-9-15/h5-11,20,25H,4H2,1-3H3,(H,22,23)
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68432
PNG
(MLS000082642 | N-(3-imidazol-1-ylpropyl)-[1]benzof...)
Show SMILES C(CNc1ncnc2c3ccccc3oc12)Cn1ccnc1
Show InChI InChI=1S/C16H15N5O/c1-2-5-13-12(4-1)14-15(22-13)16(20-10-19-14)18-6-3-8-21-9-7-17-11-21/h1-2,4-5,7,9-11H,3,6,8H2,(H,18,19,20)
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68445
PNG
(MLS000084336 | SMR000048725 | cid_667374)
Show SMILES Cc1nc2nc(=O)c3C(C4=C(CC(C)(C)CC4=O)Nc3n2[nH]1)c1ccc(F)cc1
Show InChI InChI=1S/C21H20FN5O2/c1-10-23-20-25-19(29)17-15(11-4-6-12(22)7-5-11)16-13(24-18(17)27(20)26-10)8-21(2,3)9-14(16)28/h4-7,15,24H,8-9H2,1-3H3,(H,23,25,26,29)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68447
PNG
(1-[2-[(4-benzyl-5-methyl-1,2,4-triazol-3-yl)sulfan...)
Show SMILES Cc1nnc(SCC(=O)N2CCC(CC2)C(=O)Nc2nccs2)n1Cc1ccccc1
Show InChI InChI=1S/C21H24N6O2S2/c1-15-24-25-21(27(15)13-16-5-3-2-4-6-16)31-14-18(28)26-10-7-17(8-11-26)19(29)23-20-22-9-12-30-20/h2-6,9,12,17H,7-8,10-11,13-14H2,1H3,(H,22,23,29)
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n/an/an/an/a 3.66E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68454
PNG
(4-[2-[2-[(4-ethoxybenzoyl)amino]acetyl]oxyacetyl]-...)
Show SMILES CCOC(=O)c1c(C)[nH]c(C)c1C(=O)COC(=O)CNC(=O)c1ccc(OCC)cc1
Show InChI InChI=1S/C22H26N2O7/c1-5-29-16-9-7-15(8-10-16)21(27)23-11-18(26)31-12-17(25)19-13(3)24-14(4)20(19)22(28)30-6-2/h7-10,24H,5-6,11-12H2,1-4H3,(H,23,27)
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68462
PNG
(2,5-dimethyl-4-[2-[4-(2-methylpropyl)-2,5-dioxo-1-...)
Show SMILES CCOC(=O)c1c(C)[nH]c(C)c1C(=O)CN1C(=O)NC(CC(C)C)C1=O
Show InChI InChI=1S/C18H25N3O5/c1-6-26-17(24)15-11(5)19-10(4)14(15)13(22)8-21-16(23)12(7-9(2)3)20-18(21)25/h9,12,19H,6-8H2,1-5H3,(H,20,25)
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68464
PNG
(3-imidazol-1-ylpropyl-(2-methylquinazolin-4-yl)ami...)
Show SMILES Cc1nc(NCCCn2ccnc2)c2ccccc2n1
Show InChI InChI=1S/C15H17N5/c1-12-18-14-6-3-2-5-13(14)15(19-12)17-7-4-9-20-10-8-16-11-20/h2-3,5-6,8,10-11H,4,7,9H2,1H3,(H,17,18,19)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68465
PNG
(1-[3-(3,4-dimethoxyphenyl)-1-phenyl-4-pyrazolyl]-N...)
Show SMILES COc1ccc(cc1OC)-c1nn(cc1C=Nn1cnnc1)-c1ccccc1
Show InChI InChI=1S/C20H18N6O2/c1-27-18-9-8-15(10-19(18)28-2)20-16(11-23-25-13-21-22-14-25)12-26(24-20)17-6-4-3-5-7-17/h3-14H,1-2H3
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68491
PNG
(6-(ethylthio)-3-(4-fluorophenyl)-[1,2,4]triazolo[4...)
Show SMILES CCSc1ccc2nnc(-c3ccc(F)cc3)n2n1
Show InChI InChI=1S/C13H11FN4S/c1-2-19-12-8-7-11-15-16-13(18(11)17-12)9-3-5-10(14)6-4-9/h3-8H,2H2,1H3
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n/an/an/an/a 2.82E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68498
PNG
(2-[[3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyrid...)
Show SMILES CCC(Sc1ccc2nnc(-c3ccc(F)cc3)n2n1)C(O)=O
Show InChI InChI=1S/C15H13FN4O2S/c1-2-11(15(21)22)23-13-8-7-12-17-18-14(20(12)19-13)9-3-5-10(16)6-4-9/h3-8,11H,2H2,1H3,(H,21,22)
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n/an/an/an/a 2.95E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68506
PNG
(3,7,7-trimethyl-4-phenyl-1,4,6,7,8,9-hexahydro-5H-...)
Show SMILES Cc1[nH]nc2N=C3CC(C)(C)CC(=O)C3C(c12)c1ccccc1
Show InChI InChI=1S/C19H21N3O/c1-11-15-16(12-7-5-4-6-8-12)17-13(20-18(15)22-21-11)9-19(2,3)10-14(17)23/h4-8,16-17H,9-10H2,1-3H3,(H,21,22)
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n/an/an/an/a 1.24E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68507
PNG
(4-[[3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyrid...)
Show SMILES CCOC(=O)CC(=O)CSc1ccc2nnc(-c3ccc(F)cc3)n2n1
Show InChI InChI=1S/C17H15FN4O3S/c1-2-25-16(24)9-13(23)10-26-15-8-7-14-19-20-17(22(14)21-15)11-3-5-12(18)6-4-11/h3-8H,2,9-10H2,1H3
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n/an/an/an/a 8.38E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68519
PNG
(1-[2-(3-methoxyanilino)-2-oxoethyl]triazole-4,5-di...)
Show SMILES CCOC(=O)c1nnn(CC(=O)Nc2cccc(OC)c2)c1C(=O)OCC
Show InChI InChI=1S/C17H20N4O6/c1-4-26-16(23)14-15(17(24)27-5-2)21(20-19-14)10-13(22)18-11-7-6-8-12(9-11)25-3/h6-9H,4-5,10H2,1-3H3,(H,18,22)
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM39246
PNG
(1-(4-amino-1,2,5-oxadiazol-3-yl)-5-(4-methoxypheny...)
Show SMILES CCOC(=O)c1nnn(-c2nonc2N)c1-c1ccc(OC)cc1
Show InChI InChI=1S/C14H14N6O4/c1-3-23-14(21)10-11(8-4-6-9(22-2)7-5-8)20(19-16-10)13-12(15)17-24-18-13/h4-7H,3H2,1-2H3,(H2,15,17)
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n/an/an/an/a 1.44E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68528
PNG
(1-(4-amino-1,2,5-oxadiazol-3-yl)-5-[[(4-methylphen...)
Show SMILES CCOC(=O)c1nnn(c1CSc1ccc(C)cc1)-c1nonc1N
Show InChI InChI=1S/C15H16N6O3S/c1-3-23-15(22)12-11(8-25-10-6-4-9(2)5-7-10)21(20-17-12)14-13(16)18-24-19-14/h4-7H,3,8H2,1-2H3,(H2,16,18)
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n/an/an/an/a 1.60E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM50829
PNG
(4-(6-methoxy-2-methyl-4-quinolinyl)morpholine | 4-...)
Show SMILES COc1ccc2nc(C)cc(N3CCOCC3)c2c1
Show InChI InChI=1S/C15H18N2O2/c1-11-9-15(17-5-7-19-8-6-17)13-10-12(18-2)3-4-14(13)16-11/h3-4,9-10H,5-8H2,1-2H3
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68538
PNG
(3-[(2-chloranyl-6-fluoranyl-phenyl)methylsulfanyl]...)
Show SMILES CCn1c(SCc2c(F)cccc2Cl)nnc1-c1ccco1
Show InChI InChI=1S/C15H13ClFN3OS/c1-2-20-14(13-7-4-8-21-13)18-19-15(20)22-9-10-11(16)5-3-6-12(10)17/h3-8H,2,9H2,1H3
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


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Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68545
PNG
(5-[(4-bromanylpyrazol-1-yl)methyl]-N-(pyridin-2-yl...)
Show SMILES Brc1cnn(Cc2ccc(o2)C(=O)NCc2ccccn2)c1
Show InChI InChI=1S/C15H13BrN4O2/c16-11-7-19-20(9-11)10-13-4-5-14(22-13)15(21)18-8-12-3-1-2-6-17-12/h1-7,9H,8,10H2,(H,18,21)
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM51573
PNG
(3-hydroxy-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6...)
Show SMILES Oc1ccc2c3CCCCc3c(=O)oc2c1
Show InChI InChI=1S/C13H12O3/c14-8-5-6-10-9-3-1-2-4-11(9)13(15)16-12(10)7-8/h5-7,14H,1-4H2
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


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Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68565
PNG
(5-methyl-4-(2-methyl-1-piperidinyl)-6-thieno[2,3-d...)
Show SMILES CC1CCCCN1c1ncnc2sc(C(O)=O)c(C)c12
Show InChI InChI=1S/C14H17N3O2S/c1-8-5-3-4-6-17(8)12-10-9(2)11(14(18)19)20-13(10)16-7-15-12/h7-8H,3-6H2,1-2H3,(H,18,19)
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68571
PNG
(2-(4-methoxyphenoxy)-N-methyl-N-(phenylmethyl)etha...)
Show SMILES COc1ccc(OCCN(C)Cc2ccccc2)cc1
Show InChI InChI=1S/C17H21NO2/c1-18(14-15-6-4-3-5-7-15)12-13-20-17-10-8-16(19-2)9-11-17/h3-11H,12-14H2,1-2H3
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM47709
PNG
(9-(2-thienyl)-5,6,7,9-tetrahydro-1H-[1,2,4]triazol...)
Show SMILES O=C1CCCC2=Nc3ncnn3C(C12)c1cccs1
Show InChI InChI=1S/C13H12N4OS/c18-9-4-1-3-8-11(9)12(10-5-2-6-19-10)17-13(16-8)14-7-15-17/h2,5-7,11-12H,1,3-4H2
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68585
PNG
(1-(4-amino-1,2,5-oxadiazol-3-yl)-5-[[(4-chlorophen...)
Show SMILES COC(=O)c1nnn(c1CSc1ccc(Cl)cc1)-c1nonc1N
Show InChI InChI=1S/C13H11ClN6O3S/c1-22-13(21)10-9(6-24-8-4-2-7(14)3-5-8)20(19-16-10)12-11(15)17-23-18-12/h2-5H,6H2,1H3,(H2,15,17)
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n/an/an/an/a 1.59E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68587
PNG
(3-(4-ethylpiperazin-1-yl)carbonyl-5-[(4-fluorophen...)
Show SMILES CCN1CCN(CC1)C(=O)c1ccc2c(c1)N(Cc1ccc(F)cc1)C(=O)c1ccccc1S2=O
Show InChI InChI=1S/C27H26FN3O3S/c1-2-29-13-15-30(16-14-29)26(32)20-9-12-25-23(17-20)31(18-19-7-10-21(28)11-8-19)27(33)22-5-3-4-6-24(22)35(25)34/h3-12,17H,2,13-16,18H2,1H3
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68610
PNG
((4-cyclohexyl-1-piperazinyl)-[1-(6-ethoxy-1,3-benz...)
Show SMILES CCOc1ccc2nc(sc2c1)N1CCC(CC1)C(=O)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1S/C25H36N4O2S/c1-2-31-21-8-9-22-23(18-21)32-25(26-22)29-12-10-19(11-13-29)24(30)28-16-14-27(15-17-28)20-6-4-3-5-7-20/h8-9,18-20H,2-7,10-17H2,1H3
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68611
PNG
(3-(4-methoxyphenyl)-1-phenyl-4-pyrazolecarboxylic ...)
Show SMILES COc1ccc(cc1)-c1nn(cc1C(O)=O)-c1ccccc1
Show InChI InChI=1S/C17H14N2O3/c1-22-14-9-7-12(8-10-14)16-15(17(20)21)11-19(18-16)13-5-3-2-4-6-13/h2-11H,1H3,(H,20,21)
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68615
PNG
(MLS000103823 | N-(5-methyl-1,2-oxazol-3-yl)-2-[(3-...)
Show SMILES Cc1cc(NC(=O)CSc2ccc3nnc(-c4cccs4)n3n2)no1
Show InChI InChI=1S/C15H12N6O2S2/c1-9-7-11(20-23-9)16-13(22)8-25-14-5-4-12-17-18-15(21(12)19-14)10-3-2-6-24-10/h2-7H,8H2,1H3,(H,16,20,22)
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM37210
PNG
(6-(4-methoxyphenyl)-3-methyl-N-(4-pyridyl)imidazo[...)
Show SMILES COc1ccc(cc1)-c1cn2c(C)c(sc2n1)C(=O)Nc1ccncc1
Show InChI InChI=1S/C19H16N4O2S/c1-12-17(18(24)21-14-7-9-20-10-8-14)26-19-22-16(11-23(12)19)13-3-5-15(25-2)6-4-13/h3-11H,1-2H3,(H,20,21,24)
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68622
PNG
(2-[[3-(3,4-dimethoxyphenyl)-[1,2,4]triazolo[4,3-b]...)
Show SMILES COC(=O)CSc1ccc2nnc(-c3ccc(OC)c(OC)c3)n2n1
Show InChI InChI=1S/C16H16N4O4S/c1-22-11-5-4-10(8-12(11)23-2)16-18-17-13-6-7-14(19-20(13)16)25-9-15(21)24-3/h4-8H,9H2,1-3H3
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68630
PNG
((2-ethoxy-2-oxidanylidene-ethyl) 4-oxidanylbenzoat...)
Show SMILES CCOC(=O)COC(=O)c1ccc(O)cc1
Show InChI InChI=1S/C11H12O5/c1-2-15-10(13)7-16-11(14)8-3-5-9(12)6-4-8/h3-6,12H,2,7H2,1H3
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
Glycogen synthase kinase-3


(Homo sapiens (human))
BDBM68636
PNG
(MLS000110763 | SMR000106692 | [3-(3,4-dimethoxyphe...)
Show SMILES COc1ccc(cc1OC)-c1nn(cc1CO)-c1ccccc1
Show InChI InChI=1S/C18H18N2O3/c1-22-16-9-8-13(10-17(16)23-2)18-14(12-21)11-20(19-18)15-6-4-3-5-7-15/h3-11,21H,12H2,1-2H3
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n/an/an/an/a>3.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2TX3CTT
More data for this
Ligand-Target Pair
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* indicates data uncertainty>20%