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PubChem AID 435026

Compile Data Set for Download or QSAR

Found 1011 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74548
PNG
(4-Amino-isothiazole-3,5-dicarboxylic acid 3-amide ...)
Show SMILES CC(C)(C)NC(=O)C(N(Cc1ccc(F)cc1)C(=O)c1snc(C(N)=O)c1N)c1ccco1
Show InChI InChI=1S/C22H24FN5O4S/c1-22(2,3)26-20(30)17(14-5-4-10-32-14)28(11-12-6-8-13(23)9-7-12)21(31)18-15(24)16(19(25)29)27-33-18/h4-10,17H,11,24H2,1-3H3,(H2,25,29)(H,26,30)
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n/an/an/an/a>5.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM71628
PNG
(6-Amino-5-(3-dimethylamino-propyl)-5H-pyrrolo[2,3-...)
Show SMILES CN(C)CCCn1c(N)c(C#N)c2nc(C#N)c(nc12)C#N
Show InChI InChI=1S/C14H14N8/c1-21(2)4-3-5-22-13(18)9(6-15)12-14(22)20-11(8-17)10(7-16)19-12/h3-5,18H2,1-2H3
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n/an/an/an/a 2.50E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74549
PNG
(MLS000033131 | N-(3-Fluoro-phenyl)-4-[(tetrahydro-...)
Show SMILES Fc1cccc(NC(=O)c2ccc(cc2)S(=O)(=O)NCC2CCCO2)c1
Show InChI InChI=1S/C18H19FN2O4S/c19-14-3-1-4-15(11-14)21-18(22)13-6-8-17(9-7-13)26(23,24)20-12-16-5-2-10-25-16/h1,3-4,6-9,11,16,20H,2,5,10,12H2,(H,21,22)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM48520
PNG
(1-(4-Ethyl-phenyl)-2-(4H-[1,2,4]triazol-3-ylsulfan...)
Show SMILES CCc1ccc(cc1)C(=O)CSc1nnc[nH]1
Show InChI InChI=1S/C12H13N3OS/c1-2-9-3-5-10(6-4-9)11(16)7-17-12-13-8-14-15-12/h3-6,8H,2,7H2,1H3,(H,13,14,15)
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Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM52121
PNG
(4-[(E)-2-(1,3-benzothiazol-2-yl)-2-cyano-vinyl]pip...)
Show SMILES CCOC(=O)N1CCN(CC1)\C=C(/C#N)c1nc2ccccc2s1
Show InChI InChI=1S/C17H18N4O2S/c1-2-23-17(22)21-9-7-20(8-10-21)12-13(11-18)16-19-14-5-3-4-6-15(14)24-16/h3-6,12H,2,7-10H2,1H3/b13-12+
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74587
PNG
(2-amino-1-(2-oxolanylmethyl)-3-pyrrolo[3,2-b]quino...)
Show SMILES Nc1c(C(=O)OC2CCCCC2)c2nc3ccccc3nc2n1CC1CCCO1
Show InChI InChI=1S/C22H26N4O3/c23-20-18(22(27)29-14-7-2-1-3-8-14)19-21(26(20)13-15-9-6-12-28-15)25-17-11-5-4-10-16(17)24-19/h4-5,10-11,14-15H,1-3,6-9,12-13,23H2
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n/an/an/an/a 2.74E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74590
PNG
(2-cyano-2-[3-(4-methyl-1-piperidinyl)-2-quinoxalin...)
Show SMILES CC1CCN(CC1)c1nc2ccccc2nc1C(C#N)C(=O)OC1CCCCC1
Show InChI InChI=1S/C23H28N4O2/c1-16-11-13-27(14-12-16)22-21(25-19-9-5-6-10-20(19)26-22)18(15-24)23(28)29-17-7-3-2-4-8-17/h5-6,9-10,16-18H,2-4,7-8,11-14H2,1H3
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n/an/an/an/a 1.45E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74591
PNG
(2-azanylidene-N-(1,3-benzodioxol-5-ylmethyl)-10-me...)
Show SMILES CCCn1c2nc3c(C)cccn3c(=O)c2cc(C(=O)NCc2ccc3OCOc3c2)c1=N
Show InChI InChI=1S/C24H23N5O4/c1-3-8-28-20(25)16(23(30)26-12-15-6-7-18-19(10-15)33-13-32-18)11-17-22(28)27-21-14(2)5-4-9-29(21)24(17)31/h4-7,9-11,25H,3,8,12-13H2,1-2H3,(H,26,30)
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n/an/an/an/a 1.46E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74593
PNG
(MLS000040828 | N-(1-ethyl-7-methyl-3-pyrazolo[3,4-...)
Show SMILES CCn1nc(NC(=O)c2ccncc2)c2cc3ccc(C)cc3nc12
Show InChI InChI=1S/C19H17N5O/c1-3-24-18-15(11-14-5-4-12(2)10-16(14)21-18)17(23-24)22-19(25)13-6-8-20-9-7-13/h4-11H,3H2,1-2H3,(H,22,23,25)
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n/an/an/an/a 1.12E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74594
PNG
(2-amino-1-[2-(2-thenoyloxy)ethyl]pyrrolo[3,2-b]qui...)
Show SMILES CCOC(=O)c1c(N)n(CCOC(=O)c2cccs2)c2nc3ccccc3nc12
Show InChI InChI=1S/C20H18N4O4S/c1-2-27-20(26)15-16-18(23-13-7-4-3-6-12(13)22-16)24(17(15)21)9-10-28-19(25)14-8-5-11-29-14/h3-8,11H,2,9-10,21H2,1H3
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n/an/an/an/a 3.74E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74602
PNG
(2-amino-4-(3-chlorophenyl)-6-cyclopropyl-5-keto-7-...)
Show SMILES Cc1cc2OC(=N)C(C#N)C(c3cccc(Cl)c3)c2c(=O)n1C1CC1
Show InChI InChI=1S/C19H16ClN3O2/c1-10-7-15-17(19(24)23(10)13-5-6-13)16(14(9-21)18(22)25-15)11-3-2-4-12(20)8-11/h2-4,7-8,13-14,16,22H,5-6H2,1H3
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74610
PNG
(2-(methylthio)-3-pyridinecarboxylic acid [2-(2-ben...)
Show SMILES CSc1ncccc1C(=O)OCC(=O)c1cc2ccccc2o1
Show InChI InChI=1S/C17H13NO4S/c1-23-16-12(6-4-8-18-16)17(20)21-10-13(19)15-9-11-5-2-3-7-14(11)22-15/h2-9H,10H2,1H3
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74611
PNG
(1-(4-fluorophenyl)-1-cyclopentanecarboxylic acid [...)
Show SMILES Cn1c(N)c(C(=O)COC(=O)C2(CCCC2)c2ccc(F)cc2)c(=O)n(C)c1=O
Show InChI InChI=1S/C20H22FN3O5/c1-23-16(22)15(17(26)24(2)19(23)28)14(25)11-29-18(27)20(9-3-4-10-20)12-5-7-13(21)8-6-12/h5-8H,3-4,9-11,22H2,1-2H3
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n/an/an/an/a>5.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74615
PNG
((E)-3-amino-2-(2-quinazolin-4-yloxyacetyl)but-2-en...)
Show SMILES CC(=N)C(C#N)C(=O)COc1ncnc2ccccc12
Show InChI InChI=1S/C14H12N4O2/c1-9(16)11(6-15)13(19)7-20-14-10-4-2-3-5-12(10)17-8-18-14/h2-5,8,11,16H,7H2,1H3
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM38385
PNG
(MLS000045293 | N-[4-(diethylsulfamoyl)phenyl]-2-(2...)
Show SMILES CCN(CC)S(=O)(=O)c1ccc(NC(=O)c2cccc3CN(CCOC)C(=O)c23)cc1
Show InChI InChI=1S/C22H27N3O5S/c1-4-25(5-2)31(28,29)18-11-9-17(10-12-18)23-21(26)19-8-6-7-16-15-24(13-14-30-3)22(27)20(16)19/h6-12H,4-5,13-15H2,1-3H3,(H,23,26)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM68486
PNG
(3-(2-hydroxyanilino)-5,5-dimethyl-1-cyclohex-2-eno...)
Show SMILES CC1(C)CC(=O)C=C(C1)Nc1ccccc1O
Show InChI InChI=1S/C14H17NO2/c1-14(2)8-10(7-11(16)9-14)15-12-5-3-4-6-13(12)17/h3-7,15,17H,8-9H2,1-2H3
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM40017
PNG
(4-[(E)-2-(2-furanyl)ethenyl]-1,3-dihydro-1,5-benzo...)
Show SMILES O=C1CC(\C=C\c2ccco2)=Nc2ccccc2N1
Show InChI InChI=1S/C15H12N2O2/c18-15-10-11(7-8-12-4-3-9-19-12)16-13-5-1-2-6-14(13)17-15/h1-9H,10H2,(H,17,18)/b8-7+
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n/an/an/an/a>5.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74626
PNG
(3-cyclohexyl-6-[4-(phenylmethyl)-1-piperidinyl]-1H...)
Show SMILES O=c1cc([nH]c(=O)n1C1CCCCC1)N1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C22H29N3O2/c26-21-16-20(23-22(27)25(21)19-9-5-2-6-10-19)24-13-11-18(12-14-24)15-17-7-3-1-4-8-17/h1,3-4,7-8,16,18-19H,2,5-6,9-15H2,(H,23,27)
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n/an/an/an/a>5.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74628
PNG
(4-[4-(2-fluorophenyl)-1-piperazinyl]tetrazolo[1,5-...)
Show SMILES Fc1ccccc1N1CCN(CC1)c1nc2ccccc2n2nnnc12
Show InChI InChI=1S/C18H16FN7/c19-13-5-1-3-7-15(13)24-9-11-25(12-10-24)17-18-21-22-23-26(18)16-8-4-2-6-14(16)20-17/h1-8H,9-12H2
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n/an/an/an/a 2.71E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74641
PNG
(MLS000043729 | N-(2-furanylmethyl)-2-(2-oxo-3H-1,4...)
Show SMILES O=C(CN1CC(=O)Oc2ccccc12)NCc1ccco1
Show InChI InChI=1S/C15H14N2O4/c18-14(16-8-11-4-3-7-20-11)9-17-10-15(19)21-13-6-2-1-5-12(13)17/h1-7H,8-10H2,(H,16,18)
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n/an/an/an/a>5.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74649
PNG
(7-(2-methoxyphenyl)-5-methyl-1,7-dihydro-[1,2,4]tr...)
Show SMILES COc1ccccc1C1C(C(N)=O)C(C)=Nc2ncnn12
Show InChI InChI=1S/C14H15N5O2/c1-8-11(13(15)20)12(19-14(18-8)16-7-17-19)9-5-3-4-6-10(9)21-2/h3-7,11-12H,1-2H3,(H2,15,20)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM42770
PNG
(3-[(5-methylthiophene-3-carbonyl)amino]thiophene-2...)
Show SMILES COC(=O)c1sccc1NC(=O)c1csc(C)c1
Show InChI InChI=1S/C12H11NO3S2/c1-7-5-8(6-18-7)11(14)13-9-3-4-17-10(9)12(15)16-2/h3-6H,1-2H3,(H,13,14)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74655
PNG
(4-tert-butyl-N-[2-[4-(2-furoyl)piperazino]-2-keto-...)
Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)NCC(=O)N1CCN(CC1)C(=O)c1ccco1
Show InChI InChI=1S/C21H27N3O5S/c1-21(2,3)16-6-8-17(9-7-16)30(27,28)22-15-19(25)23-10-12-24(13-11-23)20(26)18-5-4-14-29-18/h4-9,14,22H,10-13,15H2,1-3H3
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74660
PNG
(2,3,4,5,6-pentafluoro-N-(5-methyl-1,2-oxazol-3-yl)...)
Show SMILES Cc1cc(NC(=O)c2c(F)c(F)c(F)c(F)c2F)no1
Show InChI InChI=1S/C11H5F5N2O2/c1-3-2-4(18-20-3)17-11(19)5-6(12)8(14)10(16)9(15)7(5)13/h2H,1H3,(H,17,18,19)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74662
PNG
(1-(1-azepanyl)-2-(2,4-dimethylphenoxy)ethanone | 1...)
Show SMILES Cc1ccc(OCC(=O)N2CCCCCC2)c(C)c1
Show InChI InChI=1S/C16H23NO2/c1-13-7-8-15(14(2)11-13)19-12-16(18)17-9-5-3-4-6-10-17/h7-8,11H,3-6,9-10,12H2,1-2H3
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74669
PNG
(2-(2-furanylmethylamino)-4-methyl-1H-quinolin-7-on...)
Show SMILES Cc1cc(NCc2ccco2)nc2cc(O)ccc12
Show InChI InChI=1S/C15H14N2O2/c1-10-7-15(16-9-12-3-2-6-19-12)17-14-8-11(18)4-5-13(10)14/h2-8,18H,9H2,1H3,(H,16,17)
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n/an/an/an/a 1.05E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM62798
PNG
(3-(4-ethoxy-3-methoxy-phenyl)-2-(4-fluorophenyl)-5...)
Show SMILES CCOc1ccc(cc1OC)C1N2CCCC2C(=O)N1c1ccc(F)cc1
Show InChI InChI=1S/C21H23FN2O3/c1-3-27-18-11-6-14(13-19(18)26-2)20-23-12-4-5-17(23)21(25)24(20)16-9-7-15(22)8-10-16/h6-11,13,17,20H,3-5,12H2,1-2H3
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n/an/an/an/a 2.39E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74677
PNG
(3-methyl-6-(1-piperidinyl)-1H-pyrimidine-2,4-dione...)
Show SMILES Cn1c(=O)cc([nH]c1=O)N1CCCCC1
Show InChI InChI=1S/C10H15N3O2/c1-12-9(14)7-8(11-10(12)15)13-5-3-2-4-6-13/h7H,2-6H2,1H3,(H,11,15)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM29638
PNG
(1-[4-(2-furoyl)piperazino]-3-isopropyl-pyrido[1,2-...)
Show SMILES CC(C)c1cc(N2CCN(CC2)C(=O)c2ccco2)n2c3ccccc3nc2c1C#N
Show InChI InChI=1S/C24H23N5O2/c1-16(2)17-14-22(27-9-11-28(12-10-27)24(30)21-8-5-13-31-21)29-20-7-4-3-6-19(20)26-23(29)18(17)15-25/h3-8,13-14,16H,9-12H2,1-2H3
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n/an/an/an/a 1.61E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74688
PNG
(5-[(3,3-dimethyl-5-oxidanylidene-cyclohexylidene)a...)
Show SMILES CC1(C)CC(=O)C=C(C1)Nc1ccc2[nH]c(=O)[nH]c2c1
Show InChI InChI=1S/C15H15N3O2/c1-15(2)7-10(5-11(19)8-15)16-9-3-4-12-13(6-9)18-14(20)17-12/h3-6,16H,7-8H2,1-2H3
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM51605
PNG
((6-oxidanylidene-7,8,9,10-tetrahydrobenzo[c]chrome...)
Show SMILES O=C(Oc1ccc2c3CCCCc3c(=O)oc2c1)c1ccco1
Show InChI InChI=1S/C18H14O5/c19-17-14-5-2-1-4-12(14)13-8-7-11(10-16(13)23-17)22-18(20)15-6-3-9-21-15/h3,6-10H,1-2,4-5H2
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n/an/an/an/a 1.96E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74700
PNG
(3-(4-Formyl-5-methyl-pyrazol-1-yl)-propionic acid ...)
Show SMILES Cc1c(C=O)cnn1CCC(O)=O
Show InChI InChI=1S/C8H10N2O3/c1-6-7(5-11)4-9-10(6)3-2-8(12)13/h4-5H,2-3H2,1H3,(H,12,13)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74702
PNG
(2-[4-(4-Fluoro-benzenesulfonyl)-[1,4]diazepan-1-yl...)
Show SMILES Cc1ccc2cc(C#N)c(nc2c1)N1CCCN(CC1)S(=O)(=O)c1ccc(F)cc1
Show InChI InChI=1S/C22H21FN4O2S/c1-16-3-4-17-14-18(15-24)22(25-21(17)13-16)26-9-2-10-27(12-11-26)30(28,29)20-7-5-19(23)6-8-20/h3-8,13-14H,2,9-12H2,1H3
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n/an/an/an/a 2.48E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74705
PNG
((4E)-2-(2-furfuryl)-4-[[(3-keto-1,5-dimethyl-2-phe...)
Show SMILES Cc1c(NC=C2C(=O)N(Cc3ccco3)C(=O)c3ccccc23)c(=O)n(-c2ccccc2)n1C
Show InChI InChI=1S/C26H22N4O4/c1-17-23(26(33)30(28(17)2)18-9-4-3-5-10-18)27-15-22-20-12-6-7-13-21(20)24(31)29(25(22)32)16-19-11-8-14-34-19/h3-15,27H,16H2,1-2H3
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n/an/an/an/a 2.27E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74706
PNG
(1-Ethoxy-4-oxy-3-thiophen-2-yl-1H-quinoxalin-2-one...)
Show SMILES CCOn1c2ccccc2[n+]([O-])c(-c2cccs2)c1=O
Show InChI InChI=1S/C14H12N2O3S/c1-2-19-16-11-7-4-3-6-10(11)15(18)13(14(16)17)12-8-5-9-20-12/h3-9H,2H2,1H3
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n/an/an/an/a 9.72E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74708
PNG
(2-(1H-benzimidazol-2-ylmethylsulfanyl)-5-(2,4-dich...)
Show SMILES Clc1ccc(-c2nnc(SCc3nc4ccccc4[nH]3)o2)c(Cl)c1
Show InChI InChI=1S/C16H10Cl2N4OS/c17-9-5-6-10(11(18)7-9)15-21-22-16(23-15)24-8-14-19-12-3-1-2-4-13(12)20-14/h1-7H,8H2,(H,19,20)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74710
PNG
(8-(5-Phenyl-2-p-tolyl-pyrazolo[1,5-a]pyrimidin-7-y...)
Show SMILES Cc1ccc(cc1)-c1cc2nc(cc(N3CCC4(CC3)OCCO4)n2n1)-c1ccccc1
Show InChI InChI=1S/C26H26N4O2/c1-19-7-9-21(10-8-19)23-17-24-27-22(20-5-3-2-4-6-20)18-25(30(24)28-23)29-13-11-26(12-14-29)31-15-16-32-26/h2-10,17-18H,11-16H2,1H3
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n/an/an/an/a 5.56E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74711
PNG
((4Z)-2-(2-furanyl)-4-[(4-methoxyanilino)methyliden...)
Show SMILES COc1ccc(cc1)N=Cc1nc(oc1O)-c1ccco1
Show InChI InChI=1S/C15H12N2O4/c1-19-11-6-4-10(5-7-11)16-9-12-15(18)21-14(17-12)13-3-2-8-20-13/h2-9,18H,1H3
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n/an/an/an/a 5.86E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM41489
PNG
((4Z)-2-(4-fluorophenyl)-4-[(2-methyl-1H-indol-3-yl...)
Show SMILES Cc1[nH]c2ccccc2c1\C=C1/N=C(OC1=O)c1ccc(F)cc1
Show InChI InChI=1S/C19H13FN2O2/c1-11-15(14-4-2-3-5-16(14)21-11)10-17-19(23)24-18(22-17)12-6-8-13(20)9-7-12/h2-10,21H,1H3/b17-10-
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n/an/an/an/a>2.60E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74727
PNG
(5-keto-7-(4-methoxyphenyl)-2-methyl-4-(2-pyridyl)-...)
Show SMILES CCOC(=O)C1C(O)c2c(CC1c1ccc(OC)cc1)nc(C)c(C(=O)OCC)c2-c1ccccn1
Show InChI InChI=1S/C28H30N2O6/c1-5-35-27(32)22-16(3)30-21-15-19(17-10-12-18(34-4)13-11-17)23(28(33)36-6-2)26(31)25(21)24(22)20-9-7-8-14-29-20/h7-14,19,23,26,31H,5-6,15H2,1-4H3
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n/an/an/an/a 2.75E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74730
PNG
(2-(benzamidothiocarbamoylamino)nicotinic acid meth...)
Show SMILES COC(=O)c1cccnc1NC(=S)NNC(=O)c1ccccc1
Show InChI InChI=1S/C15H14N4O3S/c1-22-14(21)11-8-5-9-16-12(11)17-15(23)19-18-13(20)10-6-3-2-4-7-10/h2-9H,1H3,(H,18,20)(H2,16,17,19,23)
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n/an/an/an/a>5.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74735
PNG
(3-(4-chlorophenyl)sulfanyl-N-(3-propan-2-yloxyprop...)
Show SMILES CC(C)OCCCNC(=O)CCSc1ccc(Cl)cc1
Show InChI InChI=1S/C15H22ClNO2S/c1-12(2)19-10-3-9-17-15(18)8-11-20-14-6-4-13(16)5-7-14/h4-7,12H,3,8-11H2,1-2H3,(H,17,18)
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n/an/an/an/a>5.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74775
PNG
(2-(2-fluoroanilino)-3-pyridinecarboxylic acid [2-[...)
Show SMILES Fc1ccccc1Nc1ncccc1C(=O)OCC(=O)NCCN1C(=O)CSC1=O
Show InChI InChI=1S/C19H17FN4O5S/c20-13-5-1-2-6-14(13)23-17-12(4-3-7-22-17)18(27)29-10-15(25)21-8-9-24-16(26)11-30-19(24)28/h1-7H,8-11H2,(H,21,25)(H,22,23)
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74780
PNG
(1-(2-methoxy-3-dibenzofuranyl)-3-(1-naphthalenyl)t...)
Show SMILES COc1cc2c(cc1NC(=S)Nc1cccc3ccccc13)oc1ccccc21
Show InChI InChI=1S/C24H18N2O2S/c1-27-23-13-18-17-10-4-5-12-21(17)28-22(18)14-20(23)26-24(29)25-19-11-6-8-15-7-2-3-9-16(15)19/h2-14H,1H3,(H2,25,26,29)
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n/an/an/an/a>5.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74794
PNG
(4-(4-Ethoxy-2-nitro-phenyl)-4-aza-tricyclo[5.2.2.0...)
Show SMILES CCOc1ccc(N2C(=O)C3C(C4CCC3C=C4)C2=O)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C18H18N2O5/c1-2-25-12-7-8-13(14(9-12)20(23)24)19-17(21)15-10-3-4-11(6-5-10)16(15)18(19)22/h3-4,7-11,15-16H,2,5-6H2,1H3
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n/an/an/an/a>5.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74800
PNG
(1-[2-(3-Cyano-8-methyl-quinolin-2-ylamino)-ethyl]-...)
Show SMILES CCOCCCNC(=S)NCCNc1nc2c(C)cccc2cc1C#N
Show InChI InChI=1S/C19H25N5OS/c1-3-25-11-5-8-22-19(26)23-10-9-21-18-16(13-20)12-15-7-4-6-14(2)17(15)24-18/h4,6-7,12H,3,5,8-11H2,1-2H3,(H,21,24)(H2,22,23,26)
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n/an/an/an/a 3.20E+4n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74804
PNG
(1-{1-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-5-hydro...)
Show SMILES CC(=O)CC(=O)c1c(C)[nH]n(-c2nc(cs2)-c2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C17H14ClN3O3S/c1-9(22)7-14(23)15-10(2)20-21(16(15)24)17-19-13(8-25-17)11-3-5-12(18)6-4-11/h3-6,8,20H,7H2,1-2H3
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74812
PNG
(3-(2-ethoxyanilino)-5-phenyl-1-cyclohex-2-enone | ...)
Show SMILES CCOc1ccccc1NC1=CC(=O)CC(C1)c1ccccc1
Show InChI InChI=1S/C20H21NO2/c1-2-23-20-11-7-6-10-19(20)21-17-12-16(13-18(22)14-17)15-8-4-3-5-9-15/h3-11,14,16,21H,2,12-13H2,1H3
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n/an/an/an/a>5.00E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM74816
PNG
((Z)-2-cyano-N-(2-ethylphenyl)-3-(5-phenylsulfanylf...)
Show SMILES CCc1ccccc1NC(=O)C(=C/c1ccc(Sc2ccccc2)o1)\C#N
Show InChI InChI=1S/C22H18N2O2S/c1-2-16-8-6-7-11-20(16)24-22(25)17(15-23)14-18-12-13-21(26-18)27-19-9-4-3-5-10-19/h3-14H,2H2,1H3,(H,24,25)/b17-14-
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n/an/an/an/a 1.53E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b


(Homo sapiens)
BDBM64782
PNG
((6E)-6-[[2-(2,6-dipyrrolidin-1-ylpyrimidin-4-yl)hy...)
Show SMILES Oc1ccccc1CN=Nc1cc(nc(n1)N1CCCC1)N1CCCC1
Show InChI InChI=1S/C19H24N6O/c26-16-8-2-1-7-15(16)14-20-23-17-13-18(24-9-3-4-10-24)22-19(21-17)25-11-5-6-12-25/h1-2,7-8,13,26H,3-6,9-12,14H2
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Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q280513R
More data for this
Ligand-Target Pair
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* indicates data uncertainty>20%