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PubChem AID 489005

Compile Data Set for Download or QSAR

Found 703 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM76806
PNG
(MLS000027319 | N-(2,3-Dihydro-benzo[1,4]dioxin-6-y...)
Show SMILES CCCn1c(nc2ccccc12)N1CCN(CC(=O)Nc2ccc3OCCOc3c2)CC1
Show InChI InChI=1S/C24H29N5O3/c1-2-9-29-20-6-4-3-5-19(20)26-24(29)28-12-10-27(11-13-28)17-23(30)25-18-7-8-21-22(16-18)32-15-14-31-21/h3-8,16H,2,9-15,17H2,1H3,(H,25,30)
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n/an/an/an/a 3.84E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM76811
PNG
(MLS000030343 | N-[[1-(2-methoxyethyl)-1,2,3,4-tetr...)
Show SMILES COCCn1nnnc1C(N(CCc1ccccc1)Cc1cccs1)c1ccccn1
Show InChI InChI=1S/C23H26N6OS/c1-30-16-15-29-23(25-26-27-29)22(21-11-5-6-13-24-21)28(18-20-10-7-17-31-20)14-12-19-8-3-2-4-9-19/h2-11,13,17,22H,12,14-16,18H2,1H3
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n/an/an/an/a 4.87E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM76818
PNG
((4-Methyl-piperidin-1-yl)-[1-(3-phenyl-propyl)-pip...)
Show SMILES CC1CCN(CC1)C(=O)C1CCN(CCCc2ccccc2)CC1
Show InChI InChI=1S/C21H32N2O/c1-18-9-16-23(17-10-18)21(24)20-11-14-22(15-12-20)13-5-8-19-6-3-2-4-7-19/h2-4,6-7,18,20H,5,8-17H2,1H3
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n/an/an/an/a 7.69E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM76824
PNG
(2-[4-(4-phenylthiazol-2-yl)piperazino]-N-piperonyl...)
Show SMILES O=C(CN1CCN(CC1)c1nc(cs1)-c1ccccc1)NCc1ccc2OCOc2c1
Show InChI InChI=1S/C23H24N4O3S/c28-22(24-13-17-6-7-20-21(12-17)30-16-29-20)14-26-8-10-27(11-9-26)23-25-19(15-31-23)18-4-2-1-3-5-18/h1-7,12,15H,8-11,13-14,16H2,(H,24,28)
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n/an/an/an/a 3.41E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM76867
PNG
(2,5-dimethyl-1-(phenothiazine-10-carbonyl)-4-piper...)
Show SMILES CC1CC(=O)C(C)CN1C(=O)N1c2ccccc2Sc2ccccc12
Show InChI InChI=1S/C20H20N2O2S/c1-13-12-21(14(2)11-17(13)23)20(24)22-15-7-3-5-9-18(15)25-19-10-6-4-8-16(19)22/h3-10,13-14H,11-12H2,1-2H3
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n/an/an/an/a 8.31E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM76889
PNG
(2-(1H-benzimidazol-2-ylmethylsulfanyl)-1-[4-(3-chl...)
Show SMILES Clc1cccc(c1)N1CCN(CC1)C(=O)CSCc1nc2ccccc2[nH]1
Show InChI InChI=1S/C20H21ClN4OS/c21-15-4-3-5-16(12-15)24-8-10-25(11-9-24)20(26)14-27-13-19-22-17-6-1-2-7-18(17)23-19/h1-7,12H,8-11,13-14H2,(H,22,23)
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n/an/an/an/a 3.55E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM76905
PNG
((5-phenyl-1,3,4-oxadiazol-2-yl)methyl 1-benzyl-5-c...)
Show SMILES Cc1nn(Cc2ccccc2)c(Cl)c1C(=O)OCc1nnc(o1)-c1ccccc1
Show InChI InChI=1S/C21H17ClN4O3/c1-14-18(19(22)26(25-14)12-15-8-4-2-5-9-15)21(27)28-13-17-23-24-20(29-17)16-10-6-3-7-11-16/h2-11H,12-13H2,1H3
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n/an/an/an/a 3.04E+4n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM76911
PNG
(2-(1H-benzimidazol-2-ylsulfanyl)-N-(2,3-dihydro-1,...)
Show SMILES O=C(CSc1nc2ccccc2[nH]1)Nc1ccc2OCCOc2c1
Show InChI InChI=1S/C17H15N3O3S/c21-16(10-24-17-19-12-3-1-2-4-13(12)20-17)18-11-5-6-14-15(9-11)23-8-7-22-14/h1-6,9H,7-8,10H2,(H,18,21)(H,19,20)
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n/an/an/an/a 1.33E+4n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM76912
PNG
(2-(2-fluorophenyl)-N-(4-thiophen-2-yl-1,3-thiazol-...)
Show SMILES Fc1ccccc1CC(=O)Nc1nc(cs1)-c1cccs1
Show InChI InChI=1S/C15H11FN2OS2/c16-11-5-2-1-4-10(11)8-14(19)18-15-17-12(9-21-15)13-6-3-7-20-13/h1-7,9H,8H2,(H,17,18,19)
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n/an/an/an/a 1.98E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM76914
PNG
(MLS000087888 | N-[2-(4-methylphenyl)-2,6-dihydro-4...)
Show SMILES Cc1ccc(cc1)-n1nc2CSCc2c1NC(=O)c1cccs1
Show InChI InChI=1S/C17H15N3OS2/c1-11-4-6-12(7-5-11)20-16(13-9-22-10-14(13)19-20)18-17(21)15-3-2-8-23-15/h2-8H,9-10H2,1H3,(H,18,21)
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n/an/an/an/a 558n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM76921
PNG
(1-ethyl-N-(2-furanylmethyl)-6-[(4-methyl-1-piperid...)
Show SMILES CCn1cc(C(=O)NCc2ccco2)c(=O)c2cc(ccc12)S(=O)(=O)N1CCC(C)CC1
Show InChI InChI=1S/C23H27N3O5S/c1-3-25-15-20(23(28)24-14-17-5-4-12-31-17)22(27)19-13-18(6-7-21(19)25)32(29,30)26-10-8-16(2)9-11-26/h4-7,12-13,15-16H,3,8-11,14H2,1-2H3,(H,24,28)
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n/an/an/an/a 3.82E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM37052
PNG
(5-ethyl-N-[2-(2-phenyl-1,3-thiazol-4-yl)ethyl]thio...)
Show SMILES CCc1ccc(s1)S(=O)(=O)NCCc1csc(n1)-c1ccccc1
Show InChI InChI=1S/C17H18N2O2S3/c1-2-15-8-9-16(23-15)24(20,21)18-11-10-14-12-22-17(19-14)13-6-4-3-5-7-13/h3-9,12,18H,2,10-11H2,1H3
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n/an/an/an/a 4.22E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM76934
PNG
(MLS000094306 | N-(3,5-dimethoxyphenyl)-2-({[1-phen...)
Show SMILES COc1cc(NC(=O)CSCc2cnn(c2-n2cccc2)-c2ccccc2)cc(OC)c1
Show InChI InChI=1S/C24H24N4O3S/c1-30-21-12-19(13-22(14-21)31-2)26-23(29)17-32-16-18-15-25-28(20-8-4-3-5-9-20)24(18)27-10-6-7-11-27/h3-15H,16-17H2,1-2H3,(H,26,29)
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n/an/an/an/a 3.47E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM76950
PNG
(5-bromanyl-N-[2-(2-methylphenyl)-4,6-dihydrothieno...)
Show SMILES Cc1ccccc1-n1nc2CSCc2c1NC(=O)c1ccc(Br)o1
Show InChI InChI=1S/C17H14BrN3O2S/c1-10-4-2-3-5-13(10)21-16(11-8-24-9-12(11)20-21)19-17(22)14-6-7-15(18)23-14/h2-7H,8-9H2,1H3,(H,19,22)
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n/an/an/an/a 5.29E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM76951
PNG
(4-fluoranyl-N-[2-[3-[2-[(5-methyl-1,2-oxazol-3-yl)...)
Show SMILES Cc1cc(NC(=O)CSc2cn(CCNC(=O)c3ccc(F)cc3)c3ccccc23)no1
Show InChI InChI=1S/C23H21FN4O3S/c1-15-12-21(27-31-15)26-22(29)14-32-20-13-28(19-5-3-2-4-18(19)20)11-10-25-23(30)16-6-8-17(24)9-7-16/h2-9,12-13H,10-11,14H2,1H3,(H,25,30)(H,26,27,29)
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n/an/an/an/a 2.60E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM76954
PNG
(2-benzoyl-6-(2-furyl)-4-(phenoxymethyl)-1,5,2-diox...)
Show SMILES O=C(N1CC(COc2ccccc2)OC(O1)c1ccco1)c1ccccc1
Show InChI InChI=1S/C21H19NO5/c23-20(16-8-3-1-4-9-16)22-14-18(15-25-17-10-5-2-6-11-17)26-21(27-22)19-12-7-13-24-19/h1-13,18,21H,14-15H2
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n/an/an/an/a 1.24E+4n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM46002
PNG
((6-methyl-2-pyridyl)-[4-(2-pyridyl)thiazol-2-yl]am...)
Show SMILES Cc1cccc(Nc2nc(cs2)-c2ccccn2)n1
Show InChI InChI=1S/C14H12N4S/c1-10-5-4-7-13(16-10)18-14-17-12(9-19-14)11-6-2-3-8-15-11/h2-9H,1H3,(H,16,17,18)
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n/an/an/an/a 7.24E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM76985
PNG
(1-(2,3-dimethylphenyl)-4-(4-phenoxybutanoyl)pipera...)
Show SMILES Cc1cccc(N2CCN(CC2)C(=O)CCCOc2ccccc2)c1C
Show InChI InChI=1S/C22H28N2O2/c1-18-8-6-11-21(19(18)2)23-13-15-24(16-14-23)22(25)12-7-17-26-20-9-4-3-5-10-20/h3-6,8-11H,7,12-17H2,1-2H3
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n/an/an/an/a 5.65E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM76991
PNG
(3'-hydroxy-2,5'-dimethyl-1',3'-dih...)
Show SMILES Cc1[nH]c2ccccc2c1C1(O)C(=O)Nc2ccc(C)cc12
Show InChI InChI=1S/C18H16N2O2/c1-10-7-8-15-13(9-10)18(22,17(21)20-15)16-11(2)19-14-6-4-3-5-12(14)16/h3-9,19,22H,1-2H3,(H,20,21)
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n/an/an/an/a 8.82E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM77000
PNG
(3-[5-(2-biphenylyl)-1,2,4-oxadiazol-3-yl]pyridine ...)
Show SMILES c1ccc(cc1)-c1ccccc1-c1nc(no1)-c1cccnc1
Show InChI InChI=1S/C19H13N3O/c1-2-7-14(8-3-1)16-10-4-5-11-17(16)19-21-18(22-23-19)15-9-6-12-20-13-15/h1-13H
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n/an/an/an/a 8.07E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM77036
PNG
(3-(phenylmethyl)-2-(4-phenyl-1-piperazinyl)-4-quin...)
Show SMILES O=c1n(Cc2ccccc2)c(nc2ccccc12)N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C25H24N4O/c30-24-22-13-7-8-14-23(22)26-25(29(24)19-20-9-3-1-4-10-20)28-17-15-27(16-18-28)21-11-5-2-6-12-21/h1-14H,15-19H2
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n/an/an/an/a 9.51E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM45418
PNG
(1-(3,4-dihydro-1H-isoquinolin-2-yl)-2-[[5-methyl-2...)
Show SMILES Cc1oc(nc1CS(=O)(=O)CC(=O)N1CCc2ccccc2C1)-c1ccc(C)cc1
Show InChI InChI=1S/C23H24N2O4S/c1-16-7-9-19(10-8-16)23-24-21(17(2)29-23)14-30(27,28)15-22(26)25-12-11-18-5-3-4-6-20(18)13-25/h3-10H,11-15H2,1-2H3
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n/an/an/an/a 2.21E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM77061
PNG
(MLS000118728 | N-(4-fluorophenyl)-2-[[4-(4-fluorop...)
Show SMILES Cn1cccc1Cc1nnc(SCC(=O)Nc2ccc(F)cc2)n1-c1ccc(F)cc1
Show InChI InChI=1S/C22H19F2N5OS/c1-28-12-2-3-19(28)13-20-26-27-22(29(20)18-10-6-16(24)7-11-18)31-14-21(30)25-17-8-4-15(23)5-9-17/h2-12H,13-14H2,1H3,(H,25,30)
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n/an/an/an/a 2.17E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM77069
PNG
(MLS000101535 | N-(5-tetralin-6-yl-1,3,4-oxadiazol-...)
Show SMILES O=C(Nc1nnc(o1)-c1ccc2CCCCc2c1)C1COc2ccccc2O1
Show InChI InChI=1S/C21H19N3O4/c25-19(18-12-26-16-7-3-4-8-17(16)27-18)22-21-24-23-20(28-21)15-10-9-13-5-1-2-6-14(13)11-15/h3-4,7-11,18H,1-2,5-6,12H2,(H,22,24,25)
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n/an/an/an/a 1.37E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM37206
PNG
(2-(2-oxidanylidene-2-piperidin-1-yl-ethyl)sulfanyl...)
Show SMILES O=C(CSCC(=O)N1CCCCC1)Nc1nc(cs1)-c1cccs1
Show InChI InChI=1S/C16H19N3O2S3/c20-14(10-22-11-15(21)19-6-2-1-3-7-19)18-16-17-12(9-24-16)13-5-4-8-23-13/h4-5,8-9H,1-3,6-7,10-11H2,(H,17,18,20)
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n/an/an/an/a 595n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM66038
PNG
(MLS000100919 | N-(4-pyridin-2-yl-1,3-thiazol-2-yl)...)
Show SMILES O=C(Nc1nc(cs1)-c1ccccn1)C1COc2ccccc2O1
Show InChI InChI=1S/C17H13N3O3S/c21-16(15-9-22-13-6-1-2-7-14(13)23-15)20-17-19-12(10-24-17)11-5-3-4-8-18-11/h1-8,10,15H,9H2,(H,19,20,21)
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n/an/an/an/a 2.34E+4n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM77078
PNG
(MLS000106017 | N-[4-chloranyl-3-(trifluoromethyl)p...)
Show SMILES FC(F)(F)c1cc(NC(=O)c2ccco2)ccc1Cl
Show InChI InChI=1S/C12H7ClF3NO2/c13-9-4-3-7(6-8(9)12(14,15)16)17-11(18)10-2-1-5-19-10/h1-6H,(H,17,18)
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n/an/an/an/a 1.06E+4n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM77084
PNG
(MLS000109187 | N-(5-chloranylpyridin-2-yl)-3-(diet...)
Show SMILES CCN(CC)S(=O)(=O)c1cc(ccc1C)C(=O)Nc1ccc(Cl)cn1
Show InChI InChI=1S/C17H20ClN3O3S/c1-4-21(5-2)25(23,24)15-10-13(7-6-12(15)3)17(22)20-16-9-8-14(18)11-19-16/h6-11H,4-5H2,1-3H3,(H,19,20,22)
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n/an/an/an/a 2.30E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM37250
PNG
(6-(1-azepanyl)-2-(3,5-dimethyl-1H-pyrazol-4-yl)ben...)
Show SMILES Cc1n[nH]c(C)c1N1C(=O)c2cccc3c(ccc(C1=O)c23)N1CCCCCC1
Show InChI InChI=1S/C23H24N4O2/c1-14-21(15(2)25-24-14)27-22(28)17-9-7-8-16-19(26-12-5-3-4-6-13-26)11-10-18(20(16)17)23(27)29/h7-11H,3-6,12-13H2,1-2H3,(H,24,25)
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n/an/an/an/a 1.04E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM77087
PNG
(2-[(1-ethyl-2-benzimidazolyl)methylthio]-1,3-benzo...)
Show SMILES CCn1c(CSc2nc3ccccc3s2)nc2ccccc12
Show InChI InChI=1S/C17H15N3S2/c1-2-20-14-9-5-3-7-12(14)18-16(20)11-21-17-19-13-8-4-6-10-15(13)22-17/h3-10H,2,11H2,1H3
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n/an/an/an/a 5.73E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM37601
PNG
(3-(1H-benzimidazol-2-yl)-7-(diethylamino)-1-benzop...)
Show SMILES CCN(CC)c1ccc2cc(-c3nc4ccccc4[nH]3)c(=O)oc2c1
Show InChI InChI=1S/C20H19N3O2/c1-3-23(4-2)14-10-9-13-11-15(20(24)25-18(13)12-14)19-21-16-7-5-6-8-17(16)22-19/h5-12H,3-4H2,1-2H3,(H,21,22)
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n/an/an/an/a 434n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM62892
PNG
(2-[7-Oxo-7-(3-phenyl-pyrrolidin-1-yl)-heptyl]-isoi...)
Show SMILES O=C(CCCCCCN1C(=O)c2ccccc2C1=O)N1CCC(C1)c1ccccc1
Show InChI InChI=1S/C25H28N2O3/c28-23(26-17-15-20(18-26)19-10-4-3-5-11-19)14-6-1-2-9-16-27-24(29)21-12-7-8-13-22(21)25(27)30/h3-5,7-8,10-13,20H,1-2,6,9,14-18H2
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n/an/an/an/a 624n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM77101
PNG
(2-[1,3-benzodioxol-5-ylmethyl(2-thiophen-2-ylethan...)
Show SMILES O=C(Cc1cccs1)N(Cc1ccc2OCOc2c1)C(C(=O)NC1CCCC1)c1ccccc1
Show InChI InChI=1S/C27H28N2O4S/c30-25(16-22-11-6-14-34-22)29(17-19-12-13-23-24(15-19)33-18-32-23)26(20-7-2-1-3-8-20)27(31)28-21-9-4-5-10-21/h1-3,6-8,11-15,21,26H,4-5,9-10,16-18H2,(H,28,31)
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n/an/an/an/a 1.52E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM44824
PNG
(1-(10,11-Dihydro-dibenzo[b,f]azepin-5-yl)-2-[5-(4-...)
Show SMILES CC(C(=O)N1c2ccccc2CCc2ccccc12)n1nnc(n1)-c1ccc(cc1)N(C)C
Show InChI InChI=1S/C26H26N6O/c1-18(32-28-25(27-29-32)21-14-16-22(17-15-21)30(2)3)26(33)31-23-10-6-4-8-19(23)12-13-20-9-5-7-11-24(20)31/h4-11,14-18H,12-13H2,1-3H3
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n/an/an/an/a 4.20E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM77116
PNG
(1-[(1-Benzyl-1H-tetrazol-5-yl)-thiophen-2-yl-methy...)
Show SMILES CC1CCCN(C1)C(c1cccs1)c1nnnn1Cc1ccccc1
Show InChI InChI=1S/C19H23N5S/c1-15-7-5-11-23(13-15)18(17-10-6-12-25-17)19-20-21-22-24(19)14-16-8-3-2-4-9-16/h2-4,6,8-10,12,15,18H,5,7,11,13-14H2,1H3
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n/an/an/an/a 5.97E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM77124
PNG
(Benzyl-[(1-tert-butyl-1H-tetrazol-5-yl)-(4-trifluo...)
Show SMILES CCN(Cc1ccccc1)C(c1nnnn1C(C)(C)C)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C22H26F3N5/c1-5-29(15-16-9-7-6-8-10-16)19(20-26-27-28-30(20)21(2,3)4)17-11-13-18(14-12-17)22(23,24)25/h6-14,19H,5,15H2,1-4H3
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n/an/an/an/a 1.18E+4n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM66106
PNG
(7-(diethylamino)-3-(5-phenyl-1,3,4-oxadiazol-2-yl)...)
Show SMILES CCN(CC)c1ccc2cc(-c3nnc(o3)-c3ccccc3)c(=O)oc2c1
Show InChI InChI=1S/C21H19N3O3/c1-3-24(4-2)16-11-10-15-12-17(21(25)26-18(15)13-16)20-23-22-19(27-20)14-8-6-5-7-9-14/h5-13H,3-4H2,1-2H3
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n/an/an/an/a 931n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM77150
PNG
(1-(1-tert-butyl-1,2,3,4-tetrazol-5-yl)-1-(4-chloro...)
Show SMILES CC(C)(C)n1nnnc1C(N(Cc1ccco1)Cc1cccnc1)c1ccc(Cl)cc1
Show InChI InChI=1S/C23H25ClN6O/c1-23(2,3)30-22(26-27-28-30)21(18-8-10-19(24)11-9-18)29(16-20-7-5-13-31-20)15-17-6-4-12-25-14-17/h4-14,21H,15-16H2,1-3H3
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n/an/an/an/a 3.31E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM77152
PNG
(1-Ethyl-2-m-tolyloxymethyl-1H-benzoimidazole | 1-e...)
Show SMILES CCn1c(COc2cccc(C)c2)nc2ccccc12
Show InChI InChI=1S/C17H18N2O/c1-3-19-16-10-5-4-9-15(16)18-17(19)12-20-14-8-6-7-13(2)11-14/h4-11H,3,12H2,1-2H3
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n/an/an/an/a 1.30E+4n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM77207
PNG
(1-(2-methoxy-4-prop-2-enyl-phenoxy)-3-[4-(phenylme...)
Show SMILES COc1cc(CC=C)ccc1OCC(O)CN1CCC(Cc2ccccc2)CC1
Show InChI InChI=1S/C25H33NO3/c1-3-7-20-10-11-24(25(17-20)28-2)29-19-23(27)18-26-14-12-22(13-15-26)16-21-8-5-4-6-9-21/h3-6,8-11,17,22-23,27H,1,7,12-16,18-19H2,2H3
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n/an/an/an/a 6.13E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM62959
PNG
(2-(1H-benzimidazol-2-ylsulfanyl)-N-(3,4-difluoroph...)
Show SMILES Fc1ccc(NC(=O)CSc2nc3ccccc3[nH]2)cc1F
Show InChI InChI=1S/C15H11F2N3OS/c16-10-6-5-9(7-11(10)17)18-14(21)8-22-15-19-12-3-1-2-4-13(12)20-15/h1-7H,8H2,(H,18,21)(H,19,20)
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n/an/an/an/a 6.59E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM77210
PNG
(4-(2,4-dichlorobenzoyl)-1-methyl-N'-(2-phenoxy...)
Show SMILES Cn1cc(cc1C(=O)NN=C(N)COc1ccccc1)C(=O)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C21H18Cl2N4O3/c1-27-11-13(20(28)16-8-7-14(22)10-17(16)23)9-18(27)21(29)26-25-19(24)12-30-15-5-3-2-4-6-15/h2-11H,12H2,1H3,(H2,24,25)(H,26,29)
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n/an/an/an/a 3.97E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM77211
PNG
(5-[cyclohexyl(methyl)sulfamoyl]-N-(2,3-dihydro-1,4...)
Show SMILES CN(C1CCCCC1)S(=O)(=O)c1ccc2oc(C(=O)NCC3COc4ccccc4O3)c(C)c2c1
Show InChI InChI=1S/C26H30N2O6S/c1-17-21-14-20(35(30,31)28(2)18-8-4-3-5-9-18)12-13-22(21)34-25(17)26(29)27-15-19-16-32-23-10-6-7-11-24(23)33-19/h6-7,10-14,18-19H,3-5,8-9,15-16H2,1-2H3,(H,27,29)
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n/an/an/an/a 5.64E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM77212
PNG
(1-benzyl-N-phenyl-5-[(2,2,2-trifluoroacetyl)amino]...)
Show SMILES FC(F)(F)C(=O)Nc1c(nnn1Cc1ccccc1)C(=O)Nc1ccccc1
Show InChI InChI=1S/C18H14F3N5O2/c19-18(20,21)17(28)23-15-14(16(27)22-13-9-5-2-6-10-13)24-25-26(15)11-12-7-3-1-4-8-12/h1-10H,11H2,(H,22,27)(H,23,28)
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n/an/an/an/a 4.59E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM77219
PNG
(1-[4-(4-fluorophenyl)-1-piperazinyl]-3-[3-(4-fluor...)
Show SMILES Cc1nn2c(C)c(CCC(=O)N3CCN(CC3)c3ccc(F)cc3)c(C)nc2c1-c1ccc(F)cc1
Show InChI InChI=1S/C28H29F2N5O/c1-18-25(12-13-26(36)34-16-14-33(15-17-34)24-10-8-23(30)9-11-24)20(3)35-28(31-18)27(19(2)32-35)21-4-6-22(29)7-5-21/h4-11H,12-17H2,1-3H3
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n/an/an/an/a 5.21E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM39672
PNG
(MLS000520606 | N-[(3-methoxyphenyl)methyl]-2-[(1-p...)
Show SMILES COc1cccc(CNC(=O)CSCc2cnn(c2-n2cccc2)-c2ccccc2)c1
Show InChI InChI=1S/C24H24N4O2S/c1-30-22-11-7-8-19(14-22)15-25-23(29)18-31-17-20-16-26-28(21-9-3-2-4-10-21)24(20)27-12-5-6-13-27/h2-14,16H,15,17-18H2,1H3,(H,25,29)
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n/an/an/an/a 3.66E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM39673
PNG
(MLS000520611 | N-(3-methoxyphenyl)-1-[(1-phenyl-5-...)
Show SMILES COc1cccc(NC(=O)C2CCN(Cc3cnn(c3-n3cccc3)-c3ccccc3)CC2)c1
Show InChI InChI=1S/C27H29N5O2/c1-34-25-11-7-8-23(18-25)29-26(33)21-12-16-30(17-13-21)20-22-19-28-32(24-9-3-2-4-10-24)27(22)31-14-5-6-15-31/h2-11,14-15,18-19,21H,12-13,16-17,20H2,1H3,(H,29,33)
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n/an/an/an/a 2.29E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM77222
PNG
(1,3-bis(2-methoxy-4-prop-2-enyl-phenoxy)propan-2-o...)
Show SMILES COc1cc(CC=C)ccc1OCC(O)COc1ccc(CC=C)cc1OC
Show InChI InChI=1S/C23H28O5/c1-5-7-17-9-11-20(22(13-17)25-3)27-15-19(24)16-28-21-12-10-18(8-6-2)14-23(21)26-4/h5-6,9-14,19,24H,1-2,7-8,15-16H2,3-4H3
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n/an/an/an/a 6.12E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM77237
PNG
(3-(5,7-dimethyl-2-phenyl-6-pyrazolo[1,5-a]pyrimidi...)
Show SMILES Cc1nc2cc(nn2c(C)c1CCC(=O)N1CCN(CC1)c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C27H29N5O/c1-20-24(21(2)32-26(28-20)19-25(29-32)22-9-5-3-6-10-22)13-14-27(33)31-17-15-30(16-18-31)23-11-7-4-8-12-23/h3-12,19H,13-18H2,1-2H3
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n/an/an/an/a 4.59E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H


(Homo sapiens (Human))
BDBM77239
PNG
(MLS000522553 | N-[[3-(3-methylphenyl)-1,2,4-oxadia...)
Show SMILES CC(C)N(Cc1nc(no1)-c1cccc(C)c1)C(=O)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C27H27N3O2/c1-19(2)30(18-24-28-26(29-32-24)23-16-10-11-20(3)17-23)27(31)25(21-12-6-4-7-13-21)22-14-8-5-9-15-22/h4-17,19,25H,18H2,1-3H3
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n/an/an/an/a 6.72E+3n/an/an/an/a



Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters

Curated by PubChem BioAssay


Assay Description
Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2B856KG
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 703 total )  |  Next  |  Last  >>
* indicates data uncertainty>20%