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PubChem AID 602150

Compile data set for download or QSAR
Found 25 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87183
PNG
(N-[(1R)-2-[4-(5-chloro-2-keto-3H-benzimidazol-1-yl...)
Show SMILES C[C@H](CN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O)NC(=O)c1cc2ccccc2[nH]1
Show InChI InChI=1S/C24H26ClN5O2/c1-15(26-23(31)21-12-16-4-2-3-5-19(16)27-21)14-29-10-8-18(9-11-29)30-22-7-6-17(25)13-20(22)28-24(30)32/h2-7,12-13,15,18,27H,8-11,14H2,1H3,(H,26,31)(H,28,32)/t15-/m1/s1
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n/an/a 9n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87119
PNG
((1R,2R)-N-[(1S)-2-[4-(5-bromo-2-keto-3H-benzimidaz...)
Show SMILES C[C@@H](CN1CCC(CC1)n1c2ccc(Br)cc2[nH]c1=O)NC(=O)[C@@H]1C[C@H]1c1ccccc1
Show InChI InChI=1S/C25H29BrN4O2/c1-16(27-24(31)21-14-20(21)17-5-3-2-4-6-17)15-29-11-9-19(10-12-29)30-23-8-7-18(26)13-22(23)28-25(30)32/h2-8,13,16,19-21H,9-12,14-15H2,1H3,(H,27,31)(H,28,32)/t16-,20-,21+/m0/s1
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n/an/a 15n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM50258084
PNG
((1R,2R)-N-(2-(4-(5-chloro-2-oxo-2,3-dihydro-1H-ben...)
Show SMILES Clc1ccc2n(C3CCN(CCNC(=O)C4C[C@H]4c4ccccc4)CC3)c(=O)[nH]c2c1
Show InChI InChI=1S/C24H27ClN4O2/c25-17-6-7-22-21(14-17)27-24(31)29(22)18-8-11-28(12-9-18)13-10-26-23(30)20-15-19(20)16-4-2-1-3-5-16/h1-7,14,18-20H,8-13,15H2,(H,26,30)(H,27,31)/t19-,20?/m0/s1
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n/an/a 15n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM50258181
PNG
(3,4-difluoro-N-(2-(4-(6-fluoro-2-oxo-2,3-dihydro-1...)
Show SMILES Fc1ccc2[nH]c(=O)n(C3CCN(CCNC(=O)c4ccc(F)c(F)c4)CC3)c2c1
Show InChI InChI=1S/C21H21F3N4O2/c22-14-2-4-18-19(12-14)28(21(30)26-18)15-5-8-27(9-6-15)10-7-25-20(29)13-1-3-16(23)17(24)11-13/h1-4,11-12,15H,5-10H2,(H,25,29)(H,26,30)
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n/an/a 22n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87215
PNG
(N-[(1S)-2-[4-(5-bromo-2-keto-3H-benzimidazol-1-yl)...)
Show SMILES C[C@@H](CN1CCC(CC1)n1c2ccc(Br)cc2[nH]c1=O)NC(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C26H27BrN4O2/c1-17(28-25(32)20-7-6-18-4-2-3-5-19(18)14-20)16-30-12-10-22(11-13-30)31-24-9-8-21(27)15-23(24)29-26(31)33/h2-9,14-15,17,22H,10-13,16H2,1H3,(H,28,32)(H,29,33)/t17-/m0/s1
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n/an/a 42n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM50258180
PNG
(4-chloro-N-(2-(4-(6-fluoro-2-oxo-2,3-dihydro-1H-be...)
Show SMILES Fc1ccc2[nH]c(=O)n(C3CCN(CCNC(=O)c4ccc(Cl)cc4)CC3)c2c1
Show InChI InChI=1S/C21H22ClFN4O2/c22-15-3-1-14(2-4-15)20(28)24-9-12-26-10-7-17(8-11-26)27-19-13-16(23)5-6-18(19)25-21(27)29/h1-6,13,17H,7-12H2,(H,24,28)(H,25,29)
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n/an/a 44n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87223
PNG
(4-fluoranyl-N-[(2S)-1-[4-(5-fluoranyl-2-oxidanylid...)
Show SMILES C[C@@H](CN1CCC(CC1)n1c2ccc(F)cc2[nH]c1=O)NC(=O)c1ccc(F)cc1
Show InChI InChI=1S/C22H24F2N4O2/c1-14(25-21(29)15-2-4-16(23)5-3-15)13-27-10-8-18(9-11-27)28-20-7-6-17(24)12-19(20)26-22(28)30/h2-7,12,14,18H,8-11,13H2,1H3,(H,25,29)(H,26,30)/t14-/m0/s1
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n/an/a 56n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87201
PNG
(N-[(1S)-2-[4-(2-keto-3H-benzimidazol-1-yl)piperidi...)
Show SMILES C[C@@H](CN1CCC(CC1)n1c2ccccc2[nH]c1=O)NC(=O)COc1ccccc1
Show InChI InChI=1S/C23H28N4O3/c1-17(24-22(28)16-30-19-7-3-2-4-8-19)15-26-13-11-18(12-14-26)27-21-10-6-5-9-20(21)25-23(27)29/h2-10,17-18H,11-16H2,1H3,(H,24,28)(H,25,29)/t17-/m0/s1
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n/an/a 57n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM50206153
PNG
(CHEMBL246032 | N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo...)
Show SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1cnc2ccccc2c1
Show InChI InChI=1S/C24H25N5O2/c30-23(18-15-17-5-1-2-6-20(17)26-16-18)25-11-14-28-12-9-19(10-13-28)29-22-8-4-3-7-21(22)27-24(29)31/h1-8,15-16,19H,9-14H2,(H,25,30)(H,27,31)
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n/an/a 59n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87245
PNG
(CHEMBL492797 | ML272 | N-(2-(4-(2-Oxo-2,3-dihydro-...)
Show SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C25H26N4O2/c30-24(20-10-9-18-5-1-2-6-19(18)17-20)26-13-16-28-14-11-21(12-15-28)29-23-8-4-3-7-22(23)27-25(29)31/h1-10,17,21H,11-16H2,(H,26,30)(H,27,31)
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n/an/a 81n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87229
PNG
((1R,2R)-N-[(1S)-2-[4-(6-fluoro-2-keto-3H-benzimida...)
Show SMILES C[C@@H](CN1CCC(CC1)n1c2cc(F)ccc2[nH]c1=O)NC(=O)[C@@H]1C[C@H]1c1ccccc1
Show InChI InChI=1S/C25H29FN4O2/c1-16(27-24(31)21-14-20(21)17-5-3-2-4-6-17)15-29-11-9-19(10-12-29)30-23-13-18(26)7-8-22(23)28-25(30)32/h2-8,13,16,19-21H,9-12,14-15H2,1H3,(H,27,31)(H,28,32)/t16-,20-,21+/m0/s1
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n/an/a 160n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87182
PNG
((1R,2R)-N-[(1S)-2-[4-(5-chloro-2-keto-3H-benzimida...)
Show SMILES C[C@@H](CN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O)NC(=O)[C@@H]1C[C@H]1c1ccccc1
Show InChI InChI=1S/C25H29ClN4O2/c1-16(27-24(31)21-14-20(21)17-5-3-2-4-6-17)15-29-11-9-19(10-12-29)30-23-8-7-18(26)13-22(23)28-25(30)32/h2-8,13,16,19-21H,9-12,14-15H2,1H3,(H,27,31)(H,28,32)/t16-,20-,21+/m0/s1
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n/an/a 230n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87239
PNG
(N-[(1S)-2-(4-keto-1-phenyl-1,3,8-triazaspiro[4.5]d...)
Show SMILES C[C@@H](CN1CCC2(CC1)N(CNC2=O)c1ccccc1)NC(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C27H30N4O2/c1-20(29-25(32)23-12-11-21-7-5-6-8-22(21)17-23)18-30-15-13-27(14-16-30)26(33)28-19-31(27)24-9-3-2-4-10-24/h2-12,17,20H,13-16,18-19H2,1H3,(H,28,33)(H,29,32)/t20-/m0/s1
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n/an/a 690n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87185
PNG
(4-amino-3-methoxy-N-[2-(4-oxo-1-phenyl-1,3,8-triaz...)
Show SMILES COc1cc(ccc1N)C(=O)NCCN1CCC2(CC1)N(CNC2=O)c1ccccc1
Show InChI InChI=1S/C23H29N5O3/c1-31-20-15-17(7-8-19(20)24)21(29)25-11-14-27-12-9-23(10-13-27)22(30)26-16-28(23)18-5-3-2-4-6-18/h2-8,15H,9-14,16,24H2,1H3,(H,25,29)(H,26,30)
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n/an/a 1.09E+3n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87240
PNG
(3,4-bis(fluoranyl)-N-[(2S)-1-(4-oxidanylidene-1-ph...)
Show SMILES C[C@@H](CN1CCC2(CC1)N(CNC2=O)c1ccccc1)NC(=O)c1ccc(F)c(F)c1
Show InChI InChI=1S/C23H26F2N4O2/c1-16(27-21(30)17-7-8-19(24)20(25)13-17)14-28-11-9-23(10-12-28)22(31)26-15-29(23)18-5-3-2-4-6-18/h2-8,13,16H,9-12,14-15H2,1H3,(H,26,31)(H,27,30)/t16-/m0/s1
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n/an/a 2.15E+3n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87184
PNG
(CHEMBL1254653 | N-[2-[1-(3-fluorophenyl)-4-keto-1,...)
Show SMILES Fc1cccc(c1)N1CNC(=O)C11CCN(CCNC(=O)c2cnc3ccccc3c2)CC1
Show InChI InChI=1S/C25H26FN5O2/c26-20-5-3-6-21(15-20)31-17-29-24(33)25(31)8-11-30(12-9-25)13-10-27-23(32)19-14-18-4-1-2-7-22(18)28-16-19/h1-7,14-16H,8-13,17H2,(H,27,32)(H,29,33)
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n/an/a 2.80E+3n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87168
PNG
(CHEMBL1254576 | N-[2-[1-(4-bromophenyl)-4-keto-1,3...)
Show SMILES Brc1ccc(cc1)N1CNC(=O)C11CCN(CCNC(=O)c2cnc3ccccc3c2)CC1
Show InChI InChI=1S/C25H26BrN5O2/c26-20-5-7-21(8-6-20)31-17-29-24(33)25(31)9-12-30(13-10-25)14-11-27-23(32)19-15-18-3-1-2-4-22(18)28-16-19/h1-8,15-16H,9-14,17H2,(H,27,32)(H,29,33)
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n/an/a 3.04E+3n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87188
PNG
(CHEMBL471257 | N-[2-(4-keto-1-phenyl-1,3,8-triazas...)
Show SMILES O=C(NCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1cc2ccccc2s1
Show InChI InChI=1S/C24H26N4O2S/c29-22(21-16-18-6-4-5-9-20(18)31-21)25-12-15-27-13-10-24(11-14-27)23(30)26-17-28(24)19-7-2-1-3-8-19/h1-9,16H,10-15,17H2,(H,25,29)(H,26,30)
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n/an/a 4.00E+3n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87170
PNG
(CHEMBL1254176 | N-[2-[1-(4-bromophenyl)-4-keto-1,3...)
Show SMILES Fc1ccc2[nH]c(cc2c1)C(=O)NCCN1CCC2(CC1)N(CNC2=O)c1ccc(Br)cc1
Show InChI InChI=1S/C24H25BrFN5O2/c25-17-1-4-19(5-2-17)31-15-28-23(33)24(31)7-10-30(11-8-24)12-9-27-22(32)21-14-16-13-18(26)3-6-20(16)29-21/h1-6,13-14,29H,7-12,15H2,(H,27,32)(H,28,33)
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UniChem

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n/an/a 5.00E+3n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87160
PNG
(CHEMBL1254996 | N-[2-[1-(3,4-difluorophenyl)-4-ket...)
Show SMILES Fc1ccc(cc1F)N1CNC(=O)C11CCN(CCNC(=O)c2cnc3ccccc3c2)CC1
Show InChI InChI=1S/C25H25F2N5O2/c26-20-6-5-19(14-21(20)27)32-16-30-24(34)25(32)7-10-31(11-8-25)12-9-28-23(33)18-13-17-3-1-2-4-22(17)29-15-18/h1-6,13-15H,7-12,16H2,(H,28,33)(H,30,34)
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n/an/a 5.48E+3n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87166
PNG
(5-fluoranyl-N-[2-[1-(4-fluorophenyl)-4-oxidanylide...)
Show SMILES Fc1ccc(cc1)N1CNC(=O)C11CCN(CCNC(=O)c2cc3cc(F)ccc3[nH]2)CC1
Show InChI InChI=1S/C24H25F2N5O2/c25-17-1-4-19(5-2-17)31-15-28-23(33)24(31)7-10-30(11-8-24)12-9-27-22(32)21-14-16-13-18(26)3-6-20(16)29-21/h1-6,13-14,29H,7-12,15H2,(H,27,32)(H,28,33)
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n/an/a 5.50E+3n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87120
PNG
(CHEMBL1254577 | N-[2-[1-(3-fluorophenyl)-4-keto-1,...)
Show SMILES Fc1cccc(c1)N1CNC(=O)C11CCN(CCNC(=O)c2ccc3ccccc3c2)CC1
Show InChI InChI=1S/C26H27FN4O2/c27-22-6-3-7-23(17-22)31-18-29-25(33)26(31)10-13-30(14-11-26)15-12-28-24(32)21-9-8-19-4-1-2-5-20(19)16-21/h1-9,16-17H,10-15,18H2,(H,28,32)(H,29,33)
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n/an/a 7.40E+3n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87231
PNG
(N-[2-(4-keto-1-phenyl-1,3,8-triazaspiro[4.5]decan-...)
Show SMILES O=C(NCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1cnc2ccccc2c1
Show InChI InChI=1S/C25H27N5O2/c31-23(20-16-19-6-4-5-9-22(19)27-17-20)26-12-15-29-13-10-25(11-14-29)24(32)28-18-30(25)21-7-2-1-3-8-21/h1-9,16-17H,10-15,18H2,(H,26,31)(H,28,32)
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n/an/a 2.00E+4n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87135
PNG
(CHEMBL1254909 | N-[2-[1-(3,4-difluorophenyl)-4-ket...)
Show SMILES Fc1ccc(cc1F)N1CNC(=O)C11CCN(CCNC(=O)c2ccc3ccccc3c2)CC1
Show InChI InChI=1S/C26H26F2N4O2/c27-22-8-7-21(16-23(22)28)32-17-30-25(34)26(32)9-12-31(13-10-26)14-11-29-24(33)20-6-5-18-3-1-2-4-19(18)15-20/h1-8,15-16H,9-14,17H2,(H,29,33)(H,30,34)
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n/an/a 2.00E+4n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87164
PNG
(CHEMBL1253820 | N-[2-[1-(4-fluorophenyl)-4-keto-1,...)
Show SMILES Fc1ccc(cc1)N1CNC(=O)C11CCN(CCNC(=O)c2cnc3ccccc3c2)CC1
Show InChI InChI=1S/C25H26FN5O2/c26-20-5-7-21(8-6-20)31-17-29-24(33)25(31)9-12-30(13-10-25)14-11-27-23(32)19-15-18-3-1-2-4-22(18)28-16-19/h1-8,15-16H,9-14,17H2,(H,27,32)(H,29,33)
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n/an/a 2.00E+4n/an/an/an/an/an/a



Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay


Assay Description
Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...


PubChem Bioassay (2011)


BindingDB Entry DOI: 10.7270/Q2SB44BV
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%