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PubChem AID 613

Compile Data Set for Download or QSAR

Found 346 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30656
PNG
(2-(4-methoxyanilino)-7-oxo-N-(2-oxolanylmethyl)-1-...)
Show SMILES COc1ccc(Nc2oc3cc(=O)ccc3cc2C(=O)NCC2CCCO2)cc1
Show InChI InChI=1S/C22H22N2O5/c1-27-17-8-5-15(6-9-17)24-22-19(21(26)23-13-18-3-2-10-28-18)11-14-4-7-16(25)12-20(14)29-22/h4-9,11-12,18,24H,2-3,10,13H2,1H3,(H,23,26)
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30663
PNG
(1,1-diketo-2-[2-keto-2-(4-methylpiperidino)ethyl]-...)
Show SMILES CC1CCN(CC1)C(=O)CN1C(=O)c2ccccc2S1(=O)=O
Show InChI InChI=1S/C15H18N2O4S/c1-11-6-8-16(9-7-11)14(18)10-17-15(19)12-4-2-3-5-13(12)22(17,20)21/h2-5,11H,6-10H2,1H3
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30665
PNG
(7-(diethylamino)-4-methyl-3-(4-morpholinylmethyl)-...)
Show SMILES CCN(CC)c1ccc2c(C)c(CN3CCOCC3)c(=O)oc2c1
Show InChI InChI=1S/C19H26N2O3/c1-4-21(5-2)15-6-7-16-14(3)17(19(22)24-18(16)12-15)13-20-8-10-23-11-9-20/h6-7,12H,4-5,8-11,13H2,1-3H3
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n/an/an/an/a 4.16E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30672
PNG
((2,2,8-Trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-y...)
Show SMILES Cc1ncc(CO)c2COC(C)(C)Oc12
Show InChI InChI=1S/C11H15NO3/c1-7-10-9(8(5-13)4-12-7)6-14-11(2,3)15-10/h4,13H,5-6H2,1-3H3
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30674
PNG
(4-(difluoromethyl)-2-(3,5-dimethyl-1-pyrazolyl)-6-...)
Show SMILES COc1ccc(cc1)-c1cc(nc(n1)-n1nc(C)cc1C)C(F)F
Show InChI InChI=1S/C17H16F2N4O/c1-10-8-11(2)23(22-10)17-20-14(9-15(21-17)16(18)19)12-4-6-13(24-3)7-5-12/h4-9,16H,1-3H3
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30676
PNG
(3-[(1-Cyclopentyl-1H-tetrazol-5-yl)-(furan-2-ylmet...)
Show SMILES Cc1ccc2[nH]c(=O)c(cc2c1)C(N(Cc1ccco1)Cc1cccnc1)c1nnnn1C1CCCC1
Show InChI InChI=1S/C28H29N7O2/c1-19-10-11-25-21(14-19)15-24(28(36)30-25)26(27-31-32-33-35(27)22-7-2-3-8-22)34(18-23-9-5-13-37-23)17-20-6-4-12-29-16-20/h4-6,9-16,22,26H,2-3,7-8,17-18H2,1H3,(H,30,36)
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30679
PNG
(1-Allyl-2-imino-10-oxo-1,10-dihydro-2H-1,9,10a-tri...)
Show SMILES COCCCNC(=O)c1cc2c(nc3ccccn3c2=O)n(CC=C)c1=N
Show InChI InChI=1S/C19H21N5O3/c1-3-9-24-16(20)13(18(25)21-8-6-11-27-2)12-14-17(24)22-15-7-4-5-10-23(15)19(14)26/h3-5,7,10,12,20H,1,6,8-9,11H2,2H3,(H,21,25)
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n/an/an/an/a 4.21E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30681
PNG
(2-furancarboxylic acid [2-(cyclopentylamino)-1-(2-...)
Show SMILES Fc1ccccc1C(OC(=O)c1ccco1)C(=O)NC1CCCC1
Show InChI InChI=1S/C18H18FNO4/c19-14-9-4-3-8-13(14)16(17(21)20-12-6-1-2-7-12)24-18(22)15-10-5-11-23-15/h3-5,8-12,16H,1-2,6-7H2,(H,20,21)
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30682
PNG
(5-(2-furanyl)-N-[1-[(2-methylphenyl)methyl]-3-pyra...)
Show SMILES Cc1ccccc1Cn1ccc(NC(=O)c2cc3nc(cc(n3n2)C(F)(F)F)-c2ccco2)n1
Show InChI InChI=1S/C23H17F3N6O2/c1-14-5-2-3-6-15(14)13-31-9-8-20(30-31)28-22(33)17-12-21-27-16(18-7-4-10-34-18)11-19(23(24,25)26)32(21)29-17/h2-12H,13H2,1H3,(H,28,30,33)
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n/an/an/an/a 4.99E+3n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30699
PNG
(2-[5-(2-Methyl-furan-3-yl)-4-m-tolyl-4H-[1,2,4]tri...)
Show SMILES Cc1nonc1NC(=O)CSc1nnc(-c2ccoc2C)n1-c1cccc(C)c1
Show InChI InChI=1S/C19H18N6O3S/c1-11-5-4-6-14(9-11)25-18(15-7-8-27-13(15)3)21-22-19(25)29-10-16(26)20-17-12(2)23-28-24-17/h4-9H,10H2,1-3H3,(H,20,24,26)
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30704
PNG
((phenylmethyl) N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a...)
Show SMILES CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@H]2[C@H]1Cc1cn(C)c3cccc2c13
Show InChI InChI=1S/C25H29N3O2/c1-27-14-18(13-26-25(29)30-16-17-7-4-3-5-8-17)11-21-20-9-6-10-22-24(20)19(12-23(21)27)15-28(22)2/h3-10,15,18,21,23H,11-14,16H2,1-2H3,(H,26,29)/t18-,21+,23+/m0/s1
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n/an/an/an/a 3.52E+3n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30724
PNG
(2-amino-6-hexyl-7-keto-N-methyl-chromene-3-carboxa...)
Show SMILES CCCCCCc1cc2cc(C(=O)NC)c(N)oc2cc1=O
Show InChI InChI=1S/C17H22N2O3/c1-3-4-5-6-7-11-8-12-9-13(17(21)19-2)16(18)22-15(12)10-14(11)20/h8-10H,3-7,18H2,1-2H3,(H,19,21)
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n/an/an/an/a 1.92E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30730
PNG
(8-(1,3-benzodioxol-5-yloxy)-7-(4-bromobenzyl)-1,3-...)
Show SMILES Cn1c2nc(Oc3ccc4OCOc4c3)n(Cc3ccc(Br)cc3)c2c(=O)n(C)c1=O
Show InChI InChI=1S/C21H17BrN4O5/c1-24-18-17(19(27)25(2)21(24)28)26(10-12-3-5-13(22)6-4-12)20(23-18)31-14-7-8-15-16(9-14)30-11-29-15/h3-9H,10-11H2,1-2H3
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30731
PNG
(1-(2-methyl-1H-indol-3-yl)-2-[4-[3-(trifluoromethy...)
Show SMILES Cc1[nH]c2ccccc2c1C(O)CN1CCN(CC1)c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C22H24F3N3O/c1-15-21(18-7-2-3-8-19(18)26-15)20(29)14-27-9-11-28(12-10-27)17-6-4-5-16(13-17)22(23,24)25/h2-8,13,20,26,29H,9-12,14H2,1H3
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30736
PNG
(2-(2-amino-3-cyanopyrrolo[3,2-b]quinoxalin-1-yl)et...)
Show SMILES Nc1c(C#N)c2nc3ccccc3nc2n1CCOC(=O)c1cccc(Br)c1
Show InChI InChI=1S/C20H14BrN5O2/c21-13-5-3-4-12(10-13)20(27)28-9-8-26-18(23)14(11-22)17-19(26)25-16-7-2-1-6-15(16)24-17/h1-7,10H,8-9,23H2
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n/an/an/an/a 4.25E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30739
PNG
(5-amino-2-(2-furanyl)-1-phenyl-2H-pyrrole-3,3,4-tr...)
Show SMILES N=C1C(C#N)C(C#N)(C#N)C(N1c1ccccc1)c1ccco1
Show InChI InChI=1S/C17H11N5O/c18-9-13-16(21)22(12-5-2-1-3-6-12)15(14-7-4-8-23-14)17(13,10-19)11-20/h1-8,13,15,21H
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30745
PNG
(5-methoxy-2-(1-piperidinylmethyl)-3-benzofurancarb...)
Show SMILES CCOC(=O)c1c(CN2CCCCC2)oc2ccc(OC)cc12
Show InChI InChI=1S/C18H23NO4/c1-3-22-18(20)17-14-11-13(21-2)7-8-15(14)23-16(17)12-19-9-5-4-6-10-19/h7-8,11H,3-6,9-10,12H2,1-2H3
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30755
PNG
(2-amino-N-cyclopentyl-1-(2-oxolanylmethyl)-3-pyrro...)
Show SMILES Nc1c(C(=O)NC2CCCC2)c2nc3ccccc3nc2n1CC1CCCO1
Show InChI InChI=1S/C21H25N5O2/c22-19-17(21(27)23-13-6-1-2-7-13)18-20(26(19)12-14-8-5-11-28-14)25-16-10-4-3-9-15(16)24-18/h3-4,9-10,13-14H,1-2,5-8,11-12,22H2,(H,23,27)
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n/an/an/an/a 1.10E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30763
PNG
(2-amino-N-(3-methylbutyl)-1-(2-oxolanylmethyl)-3-p...)
Show SMILES CC(C)CCNC(=O)c1c(N)n(CC2CCCO2)c2nc3ccccc3nc12
Show InChI InChI=1S/C21H27N5O2/c1-13(2)9-10-23-21(27)17-18-20(25-16-8-4-3-7-15(16)24-18)26(19(17)22)12-14-6-5-11-28-14/h3-4,7-8,13-14H,5-6,9-12,22H2,1-2H3,(H,23,27)
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n/an/an/an/a 1.09E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30772
PNG
(3-[[2-(3,4-dihydro-2H-quinolin-1-yl)-1-oxoethyl]am...)
Show SMILES COC(=O)c1[nH]c2cc(C)ccc2c1NC(=O)CN1CCCc2ccccc12
Show InChI InChI=1S/C22H23N3O3/c1-14-9-10-16-17(12-14)23-21(22(27)28-2)20(16)24-19(26)13-25-11-5-7-15-6-3-4-8-18(15)25/h3-4,6,8-10,12,23H,5,7,11,13H2,1-2H3,(H,24,26)
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30773
PNG
((2S)-2-(butan-2-ylcarbamoylamino)-3-phenyl-propano...)
Show SMILES CCC(C)NC(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C14H20N2O3/c1-3-10(2)15-14(19)16-12(13(17)18)9-11-7-5-4-6-8-11/h4-8,10,12H,3,9H2,1-2H3,(H,17,18)(H2,15,16,19)/t10?,12-/m0/s1
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30774
PNG
(2-azanylidene-N-[(4-fluorophenyl)methyl]-1-(3-morp...)
Show SMILES Fc1ccc(CNC(=O)c2cc3c(nc4ccccn4c3=O)n(CCCN3CCOCC3)c2=N)cc1
Show InChI InChI=1S/C26H27FN6O3/c27-19-7-5-18(6-8-19)17-29-25(34)20-16-21-24(30-22-4-1-2-10-32(22)26(21)35)33(23(20)28)11-3-9-31-12-14-36-15-13-31/h1-2,4-8,10,16,28H,3,9,11-15,17H2,(H,29,34)
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n/an/an/an/a 3.30E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30783
PNG
(2,5-diketo-8-methyl-1-thiazol-2-yl-dipyrido[1,2-e:...)
Show SMILES Cc1ccc2nc3n(-c4nccs4)c(=O)c(cc3c(=O)n2c1)C#N
Show InChI InChI=1S/C16H9N5O2S/c1-9-2-3-12-19-13-11(15(23)20(12)8-9)6-10(7-17)14(22)21(13)16-18-4-5-24-16/h2-6,8H,1H3
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n/an/an/an/a 1.43E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30794
PNG
(2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-phe...)
Show SMILES Cn1cnnc1SCC(=O)Nc1ccccc1Sc1ccccc1
Show InChI InChI=1S/C17H16N4OS2/c1-21-12-18-20-17(21)23-11-16(22)19-14-9-5-6-10-15(14)24-13-7-3-2-4-8-13/h2-10,12H,11H2,1H3,(H,19,22)
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30805
PNG
(MLS000048939 | N-(1,3-benzothiazol-2-yl)-2-(2-thie...)
Show SMILES O=C(Cc1cccs1)Nc1nc2ccccc2s1
Show InChI InChI=1S/C13H10N2OS2/c16-12(8-9-4-3-7-17-9)15-13-14-10-5-1-2-6-11(10)18-13/h1-7H,8H2,(H,14,15,16)
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30814
PNG
(2-(1H-indol-3-yl)acetic acid [3-cyano-3-(1,3-dihyd...)
Show SMILES O=C(Cc1c[nH]c2ccccc12)OCC(=O)C(C#N)c1nc2ccccc2[nH]1
Show InChI InChI=1S/C21H16N4O3/c22-10-15(21-24-17-7-3-4-8-18(17)25-21)19(26)12-28-20(27)9-13-11-23-16-6-2-1-5-14(13)16/h1-8,11,15,23H,9,12H2,(H,24,25)
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30818
PNG
(1-[1-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-2,5-...)
Show SMILES Cc1cc(C(=O)CSc2nnc(o2)-c2ccco2)c(C)n1CC1COc2ccccc2O1
Show InChI InChI=1S/C23H21N3O5S/c1-14-10-17(18(27)13-32-23-25-24-22(31-23)21-8-5-9-28-21)15(2)26(14)11-16-12-29-19-6-3-4-7-20(19)30-16/h3-10,16H,11-13H2,1-2H3
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30823
PNG
(MLS000060464 | SMR000068191 | [2-[(4,6-dimethoxypy...)
Show SMILES COc1cc(OC)nc(NC(=O)COC(=O)C2CCCCC2)n1
Show InChI InChI=1S/C15H21N3O5/c1-21-12-8-13(22-2)18-15(17-12)16-11(19)9-23-14(20)10-6-4-3-5-7-10/h8,10H,3-7,9H2,1-2H3,(H,16,17,18,19)
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30837
PNG
(1-benzyl-3-methyl-N-(3-pyridylmethyl)thieno[2,3-c]...)
Show SMILES Cc1nn(Cc2ccccc2)c2sc(cc12)C(=O)NCc1cccnc1
Show InChI InChI=1S/C20H18N4OS/c1-14-17-10-18(19(25)22-12-16-8-5-9-21-11-16)26-20(17)24(23-14)13-15-6-3-2-4-7-15/h2-11H,12-13H2,1H3,(H,22,25)
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30839
PNG
(1-(3-chlorobenzyl)-2-imidazolidinone | 1-(3-chloro...)
Show SMILES Clc1cccc(CN2CCNC2=O)c1
Show InChI InChI=1S/C10H11ClN2O/c11-9-3-1-2-8(6-9)7-13-5-4-12-10(13)14/h1-3,6H,4-5,7H2,(H,12,14)
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30856
PNG
(1-(4-methylphenyl)-2,5-bis(oxidanylidene)dipyrido[...)
Show SMILES Cc1ccc(cc1)-n1c2nc3ccccn3c(=O)c2cc(C#N)c1=O
Show InChI InChI=1S/C19H12N4O2/c1-12-5-7-14(8-6-12)23-17-15(10-13(11-20)18(23)24)19(25)22-9-3-2-4-16(22)21-17/h2-10H,1H3
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n/an/an/an/a 2.39E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30858
PNG
(MLS000093457 | N-[2-[4-(2,3-dimethylphenyl)-1-pipe...)
Show SMILES Cc1cccc(N2CCN(CCNC(=O)c3cc4CS(=O)(=O)Cc4s3)CC2)c1C
Show InChI InChI=1S/C21H27N3O3S2/c1-15-4-3-5-18(16(15)2)24-10-8-23(9-11-24)7-6-22-21(25)19-12-17-13-29(26,27)14-20(17)28-19/h3-5,12H,6-11,13-14H2,1-2H3,(H,22,25)
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30864
PNG
(8-methoxy-2-methyl-1,3,4,5-tetrahydropyrid[4,3-b]i...)
Show SMILES COc1ccc2[nH]c3CCN(C)Cc3c2c1
Show InChI InChI=1S/C13H16N2O/c1-15-6-5-13-11(8-15)10-7-9(16-2)3-4-12(10)14-13/h3-4,7,14H,5-6,8H2,1-2H3
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30866
PNG
(3-(3-fluorophenyl)-6-(methylthio)-[1,2,4]triazolo[...)
Show SMILES CSc1ccc2nnc(-c3cccc(F)c3)n2n1
Show InChI InChI=1S/C12H9FN4S/c1-18-11-6-5-10-14-15-12(17(10)16-11)8-3-2-4-9(13)7-8/h2-7H,1H3
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30870
PNG
(4-(3-methoxyphenyl)-2-(1-piperidinyl)-6-(trifluoro...)
Show SMILES COc1cccc(c1)-c1cc(nc(n1)N1CCCCC1)C(F)(F)F
Show InChI InChI=1S/C17H18F3N3O/c1-24-13-7-5-6-12(10-13)14-11-15(17(18,19)20)22-16(21-14)23-8-3-2-4-9-23/h5-7,10-11H,2-4,8-9H2,1H3
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30891
PNG
(MLS000049147 | N-(2-furanylmethyl)-7-hydroxy-2-oxo...)
Show SMILES Oc1ccc2cc(C(=O)NCc3ccco3)c(=O)oc2c1
Show InChI InChI=1S/C15H11NO5/c17-10-4-3-9-6-12(15(19)21-13(9)7-10)14(18)16-8-11-2-1-5-20-11/h1-7,17H,8H2,(H,16,18)
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n/an/an/an/a 5.90E+3n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30893
PNG
(1-[2-[2-chloro-4-(isopropylsulfamoyl)phenoxy]acety...)
Show SMILES CCOC(=O)C1CCN(CC1)C(=O)COc1ccc(cc1Cl)S(=O)(=O)NC(C)C
Show InChI InChI=1S/C19H27ClN2O6S/c1-4-27-19(24)14-7-9-22(10-8-14)18(23)12-28-17-6-5-15(11-16(17)20)29(25,26)21-13(2)3/h5-6,11,13-14,21H,4,7-10,12H2,1-3H3
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30904
PNG
(5-methyl-N-(3-pyridinylmethyl)-3-thiophenecarboxam...)
Show SMILES Cc1cc(cs1)C(=O)NCc1cccnc1
Show InChI InChI=1S/C12H12N2OS/c1-9-5-11(8-16-9)12(15)14-7-10-3-2-4-13-6-10/h2-6,8H,7H2,1H3,(H,14,15)
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30907
PNG
(MLS000053081 | N-(2-chlorophenyl)sulfonyl-1-methyl...)
Show SMILES Cn1cccc1C(=O)NS(=O)(=O)c1ccccc1Cl
Show InChI InChI=1S/C12H11ClN2O3S/c1-15-8-4-6-10(15)12(16)14-19(17,18)11-7-3-2-5-9(11)13/h2-8H,1H3,(H,14,16)
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30924
PNG
(1-butyl-5-methyl-3,7-diazabicyclo[3.3.1]nonan-9-on...)
Show SMILES CCCCC12CNCC(C)(CNC1)C2=O
Show InChI InChI=1S/C12H22N2O/c1-3-4-5-12-8-13-6-11(2,10(12)15)7-14-9-12/h13-14H,3-9H2,1-2H3
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30942
PNG
(MLS000119800 | N-(3-ethoxypropyl)-2-(4,5,6,7-tetra...)
Show SMILES CCOCCCNC(=O)Cn1cc2CCCCc2n1
Show InChI InChI=1S/C14H23N3O2/c1-2-19-9-5-8-15-14(18)11-17-10-12-6-3-4-7-13(12)16-17/h10H,2-9,11H2,1H3,(H,15,18)
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30945
PNG
(3-(4-fluorophenyl)-2-[(3-phenyl-1,2,4-oxadiazol-5-...)
Show SMILES Fc1ccc(cc1)-n1c(SCc2nc(no2)-c2ccccc2)nc2ccccc2c1=O
Show InChI InChI=1S/C23H15FN4O2S/c24-16-10-12-17(13-11-16)28-22(29)18-8-4-5-9-19(18)25-23(28)31-14-20-26-21(27-30-20)15-6-2-1-3-7-15/h1-13H,14H2
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30951
PNG
(MLS000118583 | N-(4-fluorobenzyl)-2-[[5-[(2-keto-1...)
Show SMILES Cn1c(Cn2c3ccccc3sc2=O)nnc1SCC(=O)NCc1ccc(F)cc1
Show InChI InChI=1S/C20H18FN5O2S2/c1-25-17(11-26-15-4-2-3-5-16(15)30-20(26)28)23-24-19(25)29-12-18(27)22-10-13-6-8-14(21)9-7-13/h2-9H,10-12H2,1H3,(H,22,27)
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30984
PNG
(1-(4-methylphenyl)-3-[4-(1,2,3,4-tetrahydronaphtha...)
Show SMILES Cc1ccc(cc1)-n1c(O)cc(N2CCN(CC2)C2CCc3ccccc3C2)c1O
Show InChI InChI=1S/C25H29N3O2/c1-18-6-9-21(10-7-18)28-24(29)17-23(25(28)30)27-14-12-26(13-15-27)22-11-8-19-4-2-3-5-20(19)16-22/h2-7,9-10,17,22,29-30H,8,11-16H2,1H3
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30995
PNG
(2-[2-[2-(3-methoxyphenoxy)ethoxy]ethylamino]ethano...)
Show SMILES COc1cccc(OCCOCCNCCO)c1
Show InChI InChI=1S/C13H21NO4/c1-16-12-3-2-4-13(11-12)18-10-9-17-8-6-14-5-7-15/h2-4,11,14-15H,5-10H2,1H3
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30659
PNG
(2-Amino-3-benzo[1,2,5]oxadiazol-5-yl-propionic aci...)
Show SMILES NC(Cc1ccc2nonc2c1)C(O)=O
Show InChI InChI=1S/C9H9N3O3/c10-6(9(13)14)3-5-1-2-7-8(4-5)12-15-11-7/h1-2,4,6H,3,10H2,(H,13,14)
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30671
PNG
(1,7-Dibenzyl-8-ethylamino-3-methyl-3,7-dihydro-pur...)
Show SMILES CCNc1nc2n(C)c(=O)n(Cc3ccccc3)c(=O)c2n1Cc1ccccc1
Show InChI InChI=1S/C22H23N5O2/c1-3-23-21-24-19-18(26(21)14-16-10-6-4-7-11-16)20(28)27(22(29)25(19)2)15-17-12-8-5-9-13-17/h4-13H,3,14-15H2,1-2H3,(H,23,24)
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30686
PNG
(7-Chloro-quinazolin-4-ol | 7-chloranyl-1H-quinazol...)
Show SMILES Clc1ccc2c(c1)nc[nH]c2=O
Show InChI InChI=1S/C8H5ClN2O/c9-5-1-2-6-7(3-5)10-4-11-8(6)12/h1-4H,(H,10,11,12)
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30693
PNG
(Cyclooctyl-furan-2-ylmethyl-amine | MLS000075563 |...)
Show SMILES C(NC1CCCCCCC1)c1ccco1
Show InChI InChI=1S/C13H21NO/c1-2-4-7-12(8-5-3-1)14-11-13-9-6-10-15-13/h6,9-10,12,14H,1-5,7-8,11H2
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM30695
PNG
(4-Amino-2-methyl-2H-pyrazole-3-carboxylic acid (3-...)
Show SMILES Cn1ncc(N)c1C(=O)Nc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C12H11F3N4O/c1-19-10(9(16)6-17-19)11(20)18-8-4-2-3-7(5-8)12(13,14)15/h2-6H,16H2,1H3,(H,18,20)
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n/an/an/an/a 9.90E+4n/an/a7.423



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q21N7ZG0
More data for this
Ligand-Target Pair
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* indicates data uncertainty>20%