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Cell Reactant:Phosphoehtnaolamine Methyltransferases 1 (PMT1)
Syringe Reactant:BDBM50308984
Meas. Tech.:Enzyme Inhibition
Entry Date:09/18/12
 
ΔG°:-33±3 (kJ/mole)
pH:7.5±0
Log10Kb:n/a
Temperature:278.15±0 (K)
ΔH° :-38±0.400 (kJ/mole)
ΔHobs:n/a
Ionic Strength:n/a
Corrected for ΔHioniz:n/a
Protons Released:n/a
ΔCp :n/a
Stoich. Param.:n/a
ΔS° : -0.018±0 (kJ/mole-K)
Comments:n/a
 
Citation Lee, SGHaakenson, WMcCarter, JPWilliams, DJHresko, MCJez, JM Thermodynamic evaluation of ligand binding in the plant-like phosphoethanolamine methyltransferases of the parasitic nematode Haemonchus contortus. J Biol Chem286:38060-8 (2011) [PubMed]  Article
More Info.:  Get all data from this article ,  ITC RUN data ,  Solution Info
 
Phosphoehtnaolamine Methyltransferases 1 (PMT1)
Source:n/a
Purity:n/a
Prep. Method:n/a
Name:Phosphoehtnaolamine Methyltransferases 1 (PMT1)
Synonyms:n/a
Type:Enzyme
Mol. Mass.:53531.36
Organism:Caenorhabditis elegans
Description:Q86NB3
Residue:460
Sequence:
MVNVRRANFKSFWDKYSDKPDTNSMMLNHSAEELESSDRADILASLPLLHNKDVVDIGAG
IGRFTTVLAETARWVLSTDFIDSFIKKNQERNAHLGNINYQVGDAVGLKMESNSVDLVFT
NWLMMYLSDEETVEFIFNCMRWLRSHGIVHLRESCSEPSTGRSKAKSMHDTANANPTHYR
FSSLYINLLRAIRYRDVDNKLWRFNVQWSCSVPTYIKRSNNWRQVHWLAEKVPAEDGAKG
TSFNELVELIKNTWQNEQEAWDAKLDDEKYVWTDKVFSSALTSLPSNSTFFLYTPRTVSP
YCHINAHTLAETFNANVWNTEIIPEYYRTSLTKSNNLKDQRVRFGWNQSLTDSVTYWQQK
DALFDVFVATEFLSTVDDETIRQLPNVMSDGAKFITLEPVDEVNEAEMKQRIQELGYTLK
SFTDVTDQCIEAQEQYFKDHEQLRDEKVIRKNWVLLELTH
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50308984
Source:n/a
Purity:n/a
Prep. Method:n/a
NameBDBM50308984
Synonyms:AdoCys | CHEMBL597532 | S-Adenosylhomocysteine
TypeSmall organic molecule
Emp. Form.C14H20N6O5S
Mol. Mass.384.411
SMILESN[C@H](CCSC[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r|
Structure
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