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Cell Reactant:Purine nucleoside phosphorylase
Syringe Reactant:BDBM92929
Meas. Tech.:Enzyme Inhibition
Entry Date:03/18/13
 
Δ G ° :n/a
pH:7.4±0
Log10Kb:n/a
Temperature:300.15±0 (K)
ΔH° :-51.5±1 (kJ/mole)
ΔHobs:n/a
Ionic Strength:n/a
Corrected for ΔHioniz:n/a
Protons Released:n/a
ΔCp :n/a
Stoich. Param.:n/a
ΔS° :n/a
Comments:n/a
 
Citation Edwards, AAMason, JMClinch, KTyler, PCEvans, GBSchramm, VL Altered enthalpy-entropy compensation in picomolar transition state analogues of human purine nucleoside phosphorylase. Biochemistry48:5226-38 (2009) [PubMed]  Article
More Info.:  Get all data from this article ,  ITC RUN data
 
Purine nucleoside phosphorylase
Source:n/a
Purity:n/a
Prep. Method:n/a
Name:Purine nucleoside phosphorylase
Synonyms:Inosine phosphorylase | Inosine-guanosine phosphorylase | Purine nucleoside phosphorylase (PNPase)
Type:Enzyme
Mol. Mass.:32119.53
Organism:Homo sapiens (Human)
Description:n/a
Residue:289
Sequence:
MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRST
VPGHAGRLVFGFLNGRACVMMQGRFHMYEGYPLWKVTFPVRVFHLLGVDTLVVTNAAGGL
NPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALSTWKQ
MGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSL
ITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM92929
Source:n/a
Purity:n/a
Prep. Method:n/a
NameBDBM92929
Synonyms:Immucillins, 13
TypeSmall molecule
Emp. Form.C11H14N4O3
Mol. Mass.250.2539
SMILESO[C@H]1CN(Cc2c[nH]c3c2nc[nH]c3=O)C[C@@H]1O |r|
Structure
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Last update November 1, 2007
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