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Cell Reactant:Intestinal fatty acid-binding protein (hIFABP)
Syringe Reactant:BDBM50085042
Meas. Tech.:Enzyme Inhibition
Entry Date:10/05/15
 
ΔG°:-31.9±0.630 (kJ/mole)
pH:8±0
Log10Kb:5.37± n/a
Temperature:310.15±0 (K)
ΔH° :-6.62±2.60 (kJ/mole)
ΔHobs:n/a
Ionic Strength:n/a
Corrected for ΔHioniz:n/a
Protons Released:n/a
ΔCp :n/a
Stoich. Param.:n/a
ΔS° : 0.0816±0.00640 (kJ/mole-K)
Comments:n/a
 
Citation Patil, RLaguerre, AWielens, JHeadey, SJWilliams, MLHughes, MLMohanty, BPorter, CJScanlon, MJ Characterization of two distinct modes of drug binding to human intestinal fatty acid binding protein. ACS Chem Biol9:2526-34 (2014) [PubMed]  Article
More Info.:  Get all data from this article ,  ITC RUN data
 
Intestinal fatty acid-binding protein (hIFABP)
Source:n/a
Purity:n/a
Prep. Method:n/a
Name:Intestinal fatty acid-binding protein (hIFABP)
Synonyms:FABPI | Fatty acid binding protein intestinal | Fatty acid-binding protein, intestinal | I-FABP
Type:Protein
Mol. Mass.:15207.56
Organism:Homo sapiens (Human)
Description:n/a
Residue:132
Sequence:
MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSAFRNIE
VVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNGNELNTVREIIGDELVQTYVY
EGVEAKRIFKKD
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50085042
Source:n/a
Purity:n/a
Prep. Method:n/a
NameBDBM50085042
Synonyms:2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester | CHEMBL672 | FENOFIBRATE | FNF | Fenofibric acid | Finofibrate | Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate | Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate | Lipantil (TN) | Procetofen | Tricor (TN) | propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate
TypeSmall organic molecule
Emp. Form.C20H21ClO4
Mol. Mass.360.831
SMILESCC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c1ccc(Cl)cc1
Structure
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Last update November 1, 2007
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