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Cell Reactant:Intestinal fatty acid-binding protein (hIFABP)
Syringe Reactant:BDBM50099491
Meas. Tech.:Enzyme Inhibition
Entry Date:10/05/15
 
ΔG°:-35.1±1 (kJ/mole)
pH:8±0
Log10Kb:5.91± n/a
Temperature:310.15±0 (K)
ΔH° :-24.5±3.5 (kJ/mole)
ΔHobs:n/a
Ionic Strength:n/a
Corrected for ΔHioniz:n/a
Protons Released:n/a
ΔCp :n/a
Stoich. Param.:n/a
ΔS° : 0.0345±0.0130 (kJ/mole-K)
Comments:n/a
 
Citation Patil, RLaguerre, AWielens, JHeadey, SJWilliams, MLHughes, MLMohanty, BPorter, CJScanlon, MJ Characterization of two distinct modes of drug binding to human intestinal fatty acid binding protein. ACS Chem Biol9:2526-34 (2014) [PubMed]  Article
More Info.:  Get all data from this article ,  ITC RUN data
 
Intestinal fatty acid-binding protein (hIFABP)
Source:n/a
Purity:n/a
Prep. Method:n/a
Name:Intestinal fatty acid-binding protein (hIFABP)
Synonyms:FABPI | Fatty acid binding protein intestinal | Fatty acid-binding protein, intestinal | I-FABP
Type:Protein
Mol. Mass.:15207.56
Organism:Homo sapiens (Human)
Description:n/a
Residue:132
Sequence:
MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSAFRNIE
VVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNGNELNTVREIIGDELVQTYVY
EGVEAKRIFKKD
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50099491
Source:n/a
Purity:n/a
Prep. Method:n/a
NameBDBM50099491
Synonyms:2-(4-(2-(3-cyclohexyl-1-(4-cyclohexylbutyl)ureido)ethyl)phenylthio)-2-methylpropanoic acid | 2-(4-{2-[3-Cyclohexyl-1-(4-cyclohexyl-butyl)-ureido]-ethyl}-phenylsulfanyl)-2-methyl-propionic acid | CHEMBL21241 | GW7647 | cid_3392731
TypeSmall organic molecule
Emp. Form.C29H46N2O3S
Mol. Mass.502.752
SMILESCC(C)(Sc1ccc(CCN(CCCCC2CCCCC2)C(=O)NC2CCCCC2)cc1)C(O)=O
Structure
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Last update November 1, 2007
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